Core Insights - GSK's fourth-quarter results exceeded expectations, with revenue of £8.6 billion reflecting an 8% increase at constant exchange rates and core EPS rising by 14%, indicating strong performance [3][4] - The company has achieved its medium-term targets a year ahead of schedule, with sales growth and earnings progression aligning with management's projections for 2026 [4] - GSK's long-term revenue ambition of over £40 billion by 2031 was reiterated, showcasing confidence in future growth [4] Financial Performance - Specialty Medicines were a significant growth driver, increasing by 18% in the quarter, primarily due to injectable HIV products and oncology [5] - Vaccines, particularly Shingrix and the RSV vaccine Arexvy, also exceeded forecasts, compensating for a slight decline in General Medicines [5] - Cost control measures, including lower legal expenses and a favorable tax outcome, positively impacted earnings, while increased R&D spending indicates a focus on future investments [6] Guidance Outlook - For 2026, GSK has set a cautious sales growth guidance of 4-6% at constant exchange rates, incorporating a significant foreign exchange headwind [7] - Analysts view this guidance as a low bar, with consensus expectations already near the upper limit of the range, suggesting that GSK's performance could surpass these projections [8]

Core Insights - GSK reported a strong performance in 2025 with sales growth of 7% at constant exchange rates, reaching over £32 billion, and core operating profit increasing by 11% [3][6] - The company emphasized its focus on specialty medicines, which saw a significant increase of 17%, driven by respiratory, oncology, and HIV segments [5][9] - GSK's guidance for 2026 includes sales growth of 3-5% and core operating profit and EPS growth of 7-9%, alongside a proposed dividend increase of 6% to £0.70 [6][7] Financial Performance - Free cash flow rose to £4.0 billion, with £1.2 billion in Zantac payments expected in 2025, and total shareholder distributions of £4.0 billion through dividends and buybacks [1][3] - Operating margin improved by 110 basis points to 29.9%, driven by better SG&A margins and a shift towards specialty medicines [2][6] - Cash generated from operations was £8.9 billion, supporting investments and a dividend increase of 2p to 66p [3][6] Commercial and Pipeline Developments - Specialty medicines are expected to continue growing at a low double-digit percentage, with HIV products showing mid- to high single-digit growth [7][8] - The company highlighted the importance of upcoming product launches, particularly Extensa and Blenrep, with a focus on execution in 2026 [14][15] - GSK secured five FDA approvals in 2025 and initiated seven new pivotal trials, indicating a robust pipeline and commitment to accelerating development timelines [17][18] Market Trends and Strategic Focus - The company is experiencing broad-based sales growth across all regions, with notable increases in respiratory (18%), oncology (43%), and HIV (11%) segments [9][12][11] - GSK's management is prioritizing business development and simplifying operations while increasing the use of technology such as AI [4][19] - The planned acquisition of RAPT Therapeutics aims to advance the development of Ozuriquibat, a long-acting anti-IgE monoclonal antibody [19]

Legal & Regulatory - The Delaware Supreme Court rejected expert testimony linking Zantac to cancer [1] - This is a major win for the drug makers involved [1]

Core Viewpoint - GSK plc is facing a class action securities lawsuit due to alleged securities fraud related to the withdrawal of Zantac from the market, impacting investors between February 5, 2020, and August 14, 2022 [1][2]. Group 1: Lawsuit Details - The lawsuit claims that GSK misrepresented the reasons for removing Zantac from the market, stating it was based on available information and regulatory correspondence, while in reality, GSK was aware of the source of NDMA for nearly 40 years prior to the withdrawal [2]. - GSK assured investors that there was no evidence linking ranitidine therapy to cancer, which the lawsuit argues was materially false or misleading [2]. Group 2: Investor Information - Investors who suffered losses during the specified timeframe have until April 7, 2025, to request to be appointed as lead plaintiff, although participation in any recovery does not require serving as a lead plaintiff [3]. - Class members may be entitled to compensation without any out-of-pocket costs or fees, with no obligation to participate [3]. Group 3: Firm Background - Levi & Korsinsky, LLP has a strong track record in securities litigation, having secured hundreds of millions of dollars for shareholders over the past 20 years and consistently ranking among the top securities litigation firms in the United States [4].

Core Viewpoint - Rosen Law Firm is reminding purchasers of GSK plc American Depositary Receipts (ADRs) of the upcoming lead plaintiff deadline for a class action lawsuit related to the company's alleged misrepresentations regarding Zantac [1][2]. Group 1: Class Action Details - The class action pertains to GSK ADRs purchased between February 5, 2020, and August 14, 2022, with a lead plaintiff deadline set for April 7, 2025 [1][2]. - Investors who purchased GSK ADRs during the specified period may be entitled to compensation without any out-of-pocket fees through a contingency fee arrangement [1]. Group 2: Allegations Against GSK - The complaint alleges that GSK misled investors by claiming that the withdrawal of Zantac was based on available information and regulatory correspondence, while in reality, GSK had known about the source of NDMA for nearly 40 years [4][5]. - GSK assured investors that there was no causal link between ranitidine therapy and cancer, which the lawsuit claims was materially false or misleading [4][5]. - The lawsuit asserts that GSK concealed an internal study that indicated potential liability to Zantac users, leading to investor damages when the truth was revealed [5]. Group 3: Rosen Law Firm's Credentials - Rosen Law Firm emphasizes the importance of selecting qualified legal counsel with a successful track record in securities class actions, highlighting its own achievements in this area [3]. - The firm has secured significant settlements for investors, including over $438 million in 2019 alone, and has been recognized as a leader in securities class action settlements [3].

Core Viewpoint - GSK plc is facing allegations related to misleading statements regarding the withdrawal of Zantac from the market, with claims that the company was aware of the source of NDMA for nearly 40 years before the product's removal [1]. Group 1: Allegations and Legal Context - The class period for the allegations against GSK spans from February 5, 2020, to August 14, 2022 [1]. - Defendants allegedly misrepresented to investors that GSK removed Zantac based on available information and correspondence with regulators, while also claiming that there was no evidence linking ranitidine therapy to cancer [1]. - The complaint asserts that GSK's representations were materially false or misleading, as the company had prior knowledge of the NDMA source [1]. Group 2: Shareholder Actions and Deadlines - Shareholders who purchased GSK shares during the specified class period are encouraged to register for the class action, with a deadline set for April 7, 2025 [2]. - Once registered, shareholders will be enrolled in a portfolio monitoring system to receive updates on the case's progress [2]. - There is no cost or obligation for shareholders to participate in the case [2]. Group 3: Firm's Mission and Commitment - The Gross Law Firm aims to protect the rights of investors affected by deceit and illegal business practices, emphasizing the importance of responsible corporate behavior [3]. - The firm seeks recovery for investors who suffered losses due to false or misleading statements that inflated the company's stock value [3].

Core Viewpoint - A class action securities lawsuit has been filed against GSK plc, alleging securities fraud that affected investors between February 5, 2020, and August 14, 2022 [1][2]. Group 1: Lawsuit Details - The lawsuit claims that GSK misled investors regarding the removal of Zantac from the market, stating it was based on available information and regulatory correspondence, while in reality, GSK had known about the source of NDMA for nearly 40 years prior to the withdrawal [2]. - GSK assured investors that there was no evidence linking ranitidine therapy to cancer, which the lawsuit argues was materially false or misleading [2]. Group 2: Investor Participation - Investors who suffered losses during the specified timeframe have until April 7, 2025, to request to be appointed as lead plaintiff, although participation in any recovery does not require serving as a lead plaintiff [3]. - Class members may be entitled to compensation without any out-of-pocket costs or fees [3]. Group 3: Firm Background - Levi & Korsinsky has a history of securing hundreds of millions of dollars for shareholders and is recognized as one of the top securities litigation firms in the United States [4].