医药生物 证券分析师 张静含 A0230522080004 zhangjh@swsresearch.com 李敏杰 A0230523070006 limj2@swsresearch.com 联系人 2025 年 07 月 13 日 本周医药上涨 1.8%，中方限制采 购欧盟医疗器械，默沙东百亿美元 获取 COPD 新药 看好 ——医药行业周报（2025/7/7-2025/7/11） 本期投资提示： 究 / 行 业 点 评 相关研究 《本周医药上涨 3.6%，创新药及高端器械 再迎支持政策，医保目录谈判正式启动， AZ/Summit 或达成超 150 亿美元交易 — —医药行业周报（2025/6/30- 2025/7/4）》 2025/07/06 《本周医药上涨 1.6%，医保目录调整将首 度纳入商保创新药目录，荣昌泰它西普完 成超 40 亿美元授权——医药行业周报 （2025/6/23-2025/6/27）》 2025/06/29 李敏杰 (8621)23297818× limj2@swsresearch.com 请务必仔细阅读正文之后的各项信息披露与声明 本研究报告仅通过邮件提供给 中庚基金 使用。1 行 ...

Core Viewpoint - Beijing Kangchen Pharmaceutical Co., Ltd. experienced a significant stock price fluctuation, with a cumulative closing price deviation exceeding 20% over three consecutive trading days from July 9 to July 11, 2025, indicating abnormal trading activity [1][2]. Group 1: Stock Trading Abnormalities - The company's stock price increased significantly, with a cumulative closing price deviation exceeding 20% over three consecutive trading days [1]. - The company conducted a self-examination and confirmed that there were no undisclosed significant information related to the stock price fluctuations [2]. Group 2: Business Operations - The company's production and operational activities are reported to be normal, with no significant changes in daily operations [1]. - There are no major undisclosed events such as asset restructuring, stock issuance, or significant business collaborations that could impact the stock price [2]. Group 3: Sensitive Information - During the period of stock price fluctuation, company executives and major shareholders did not engage in buying or selling the company's stock [2]. - The company holds a 4.96% stake in Nuance Biotech and has exclusive rights for the clinical development and commercialization of Ensifentrine in Greater China, valued at approximately $10 billion [2].

市场概述 华见早安之声 请各位听众升级为见闻最新版APP，以便成功收听以下音频。 无惧关税来袭，标普纳指齐创新高。Robotaxi业务扩展，特斯拉收涨4.7%；英伟达三日连创新高，市值晋升4万亿美元；稀土矿股MP Materials收涨近 51%；恢复今年利润指引的达美航空涨12%。 30年期美债标售需求向好，美债价格收窄跌幅。美国失业人数后，美元指数创两周新高。比特币盘中涨超5000美元、涨破11.6万美元，创历史新高。 原油跌落两周高位、本周首跌，盘中跌超2%。黄金继续走出逾一周低位。纽铜一度反弹超3%。 亚洲时段，沪指站稳3500点，地产股掀涨停潮，黑色系商品普涨，恒指重返24000点，金融股爆发，国债集体下跌。 要闻 8月"大限"前缅甸争取特朗普猛砍关税，提议对美或可零关税。巴西总统：将与美国进行关税谈判，若无效将对等反制。 特朗普：对铜征收50%的关税，8月1日起生效。和关税抢时间，交易商开始将铜运到夏威夷。汇丰：8月1日、50%关税，沪铜和伦铜的转折点。 特朗普再催美联储迅速降息，称赞英伟达股价涨幅。特朗普政府再借美联储总部翻修"攻击"：白宫指鲍威尔"严重管理不善"。 美联储理事沃勒：可以考虑7月 ...

Merck & Co. Inc. MRK agreed on Wednesday to acquire Verona Pharma plc VRNA for $107 per American Depository Share (ADS) for a total transaction value of approximately $10 billion. Each ADS represents eight ordinary shares of Verona Pharma.Through the acquisition of this respiratory disease-focused company, Merck will add Ohtuvayre (ensifentrine), a first-in-class, selective dual inhibitor of phosphodiesterase 3 and 4 (PDE3 and PDE4), to its cardiovascular and pulmonary pipeline and portfolio.Also Read: Rege ...

【导读】恒瑞医药港股午后突然大幅拉升，最大涨幅超18% 中国基金报记者 卢鸰 千亿医药巨头突然暴涨。 7月9日，恒瑞医药港股午后突然大幅拉升，最大涨幅超18%，A股同时最高暴涨超8%。 花旗7月9日发布报告称，首次给予恒瑞医药H股买入评级，目标价为134港元，A股目标价为 123元。花旗称，市场没有充分反映恒瑞医药的BD（商务拓展）预期，以及多款创新药的快 速放量，后续的业绩和BD进展都会是重要催化剂。 7月8日晚，恒瑞医药发布公告称，近日，公司子公司广东恒瑞医药有限公司收到国家药监局 核准签发关于SHR-2173注射液和HRS-9821吸入粉雾剂的《药物临床试验批准通知书》， 将于近期开展临床试验。 据公告披露，SHR-2173注射液是公司自主研发的治疗用生物制品，能够通过靶向异常激活 的免疫细胞，发挥抗炎和抑制免疫的生物学效应，有望降低自身抗体水平，改善原发性膜性 肾病患者的疾病活动状态，为患者带来新的治疗选择。目前国内外尚无同类药物上市或在临 床研发阶段。 HRS-9821是小分子PDE3/PDE4抑制剂，可有效抑制呼吸道炎症、扩张支气管，临床拟用于 慢性阻塞性肺疾病（COPD）的维持治疗。目前全球同类 ...

Verona Pharma (VRNA) 2025 Conference June 04, 2025 11:05 AM ET Speaker0 We're gonna get started with the next session. I'm Andrew Tsai, senior biotech analyst at Jefferies, and it's my pleasure to have the Verona team with me. To my direct left, Chris Martin, CCO, and to his left, David Zaccardale, President and CEO. Welcome both of you. Thanks, Andrew. Thanks. Maybe spend one or two minutes talking about the Verona story. I think a lot of people are familiar, but there are still people unfamiliar with your ...

Company Participation in Conferences - Verona Pharma's senior management will participate in the Jefferies Global Healthcare Conference on June 4, 2025, at 11:05 a.m. ET in New York, NY [1] - The company will also be present at the Goldman Sachs 46th Annual Global Healthcare Conference on June 9, 2025, at 2:40 p.m. ET in Miami, FL [1] - Webcasts of each conference presentation will be available on the company's website [1] Company Overview - Verona Pharma is a biopharmaceutical company focused on developing therapies for chronic respiratory diseases with significant unmet medical needs [3] - The company's first commercial product, Ohtuvayre (ensifentrine), is the first inhaled therapy for the maintenance treatment of COPD that combines bronchodilator and non-steroidal anti-inflammatory activities in one molecule [3] - Ensifentrine has potential applications in non-cystic fibrosis bronchiectasis, cystic fibrosis, asthma, and other respiratory diseases [3]

Financial Data and Key Metrics Changes - The total YUPELRI business has shown strong growth, particularly in the hospital channel, recovering well post-COVID pandemic [2][3] - The company has been able to slightly increase pricing, stabilizing it after previous disruptions [12] Business Line Data and Key Metrics Changes - The hospital business for YUPELRI has been growing unit volume at a faster rate, driven by formulary wins and increased sales representative collaboration with Viatris [4][5] - The company is still in the early stages of growth for YUPELRI, indicating significant potential for future expansion [9] Market Data and Key Metrics Changes - The entry of ensifentrine has not significantly impacted the market share of YUPELRI, as it is generally added to existing therapies rather than replacing them [10][11] - The company is focused on optimizing the channel to improve net pricing and overall fulfillment processes [12] Company Strategy and Development Direction - The company is prioritizing the growth of YUPELRI in the hospital setting before considering adding new products to the sales force [14][15] - Ampreloxetine is viewed as a critical asset for future growth, with a focus on efficient commercialization strategies [30][32] Management's Comments on Operating Environment and Future Outlook - Management expressed optimism about the long-term potential of YUPELRI and Trelegy, highlighting the challenges of replicating Trelegy's success [33][35] - The company is committed to returning excess capital to shareholders while focusing on the success of YUPELRI and the development of ampreloxetine [38] Other Important Information - The company has a strong cash position with $130 million on the balance sheet and potential milestones from Trelegy and YUPELRI [31] - The development of Ampreloxetine is seen as a unique opportunity to address a significant unmet need in treating MSA patients [19][24] Q&A Session Summary Question: Are you losing patients at the initial script fill or during refills? - Management indicated that they lose patients both at the initial fill and during follow-up with regional pulmonologists [8] Question: How is the enrollment for the Ampreloxetine study progressing? - Management emphasized the importance of selecting the right patients and sites for the study, ensuring quality care throughout the process [26][27] Question: What is the long-term outlook for Trelegy and its royalties? - Management believes that Trelegy will continue to perform well in both asthma and COPD markets, with royalties reverting back to the company in 2029 [35]

Group 1 - Verona Pharma plc has launched its COPD drug Ohtuvayre (ensifentrine) and is only three quarters into the launch phase, indicating potential for significant market impact [1] - The discussion surrounding Ohtuvayre as a blockbuster drug is gaining traction, suggesting optimism about its future performance [1] Group 2 - The company operates in the biotech sector, focusing on trading around key events such as trial results and regulatory approvals [1]

Verona Pharma (VRNA) Q1 2025 Earnings Call April 29, 2025 02:11 PM ET Speaker0 Welcome to Verona Pharma's First Quarter twenty twenty five Financial Results and Operating Highlights Conference Call. At this time, all participants are in a listen only mode. I'd now like to turn the call over to Victoria Stewart, Senior Director, Investor Relations and Communications. Please go ahead. Speaker1 Thank you. Earlier this morning, Corona Pharma issued a press release announcing its financial results for the three ...