Financial Data and Key Metrics Changes - Q1 2025 sales showed stronger performance than previously guided, with 13% organic growth and 12% reported growth, driven by grafts (up 17%) and carotid shunts (up 14%) [6][13] - Gross margin for Q1 2025 was 69.2%, a 60 basis point increase year-over-year, attributed to higher average selling prices (ASPs) and lower inventory scrap [14][15] - Operating income increased 6% year-over-year to $12.6 million, with an operating margin of 21% [16] - Fully diluted EPS rose to $0.48, reflecting a 10% increase [16] - Cash and securities at the end of Q1 2025 totaled $302.5 million, up $2.8 million from the previous quarter [16] Business Line Data and Key Metrics Changes - Record sales were achieved across all five product categories: grafts, carotid shunts, catheters, valvulotomes, and patches [6][14] - Organic sales growth of 13% was driven by a 9% increase in average selling prices and a 4% increase in units sold [14] Market Data and Key Metrics Changes - By geography, EMEA sales increased by 18%, the Americas by 11%, and APAC by 3% [6] - The autograft product, which had $37 million in U.S. sales in 2024, is expected to have a market size of approximately $8 million in Europe and the rest of the world [9][10] Company Strategy and Development Direction - The company is focusing on expanding its sales force, with a target of 170 sales representatives by year-end, up from 164 [7][30] - New international sales offices are being established, including a direct office in Portugal and a new office in Zurich to enhance sales performance [8][9] - The company plans to open a pan-European RestoreFlow distribution facility in Dublin in H2 2025 [12] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in increasing guidance for 2025 sales to $245 million, up from $239 million, due to strong Q1 performance and successful price increases [13][21] - The company anticipates that exiting the Aleutia distribution agreement will improve organic growth and gross margin [17][95] - Management remains optimistic about long-term prospects in China despite current trade tensions, indicating a commitment to the market [20][38] Other Important Information - The company has received 17 out of 23 MDR CE marks, with ongoing efforts to secure additional approvals [126] - The company is implementing price increases in China to offset tariff impacts, expecting to recover about 50% of additional costs [91] Q&A Session Summary Question: What factors contributed to the increased guidance? - Management cited strong Q1 performance, better-than-expected price increases, and the positive impact of exiting the Aleutia business as key factors for increased guidance [26][30] Question: Any updates on M&A activity? - The M&A pipeline remains strong, focusing on open vascular surgery and adjacent cardiac surgery markets, with a preference for larger deals [34][77] Question: How does the company view the impact of tariffs? - Management believes the company is well-positioned due to its U.S.-only manufacturing footprint and limited reliance on imports, with plans to raise prices to offset potential tariff impacts [18][20] Question: What is the outlook for gross margins? - Management expects gross margins to be slightly lower than previous guidance but maintains a strong operating margin outlook due to sales growth and exiting lower-margin products [65][84] Question: How will the new sales representatives impact growth? - Management indicated that new sales representatives are expected to contribute to sales growth more quickly than in the past, with a ramp-up time that has improved [73][75]

Financial Data and Key Metrics Changes - Q1 2025 sales showed a 13% organic growth and a 12% reported growth, exceeding previous guidance [5] - Gross margin for Q1 2025 was 69.2%, a 60 basis point increase year-over-year, driven by higher average selling prices (ASPs) and lower inventory scrap [13][14] - Operating income increased 6% year-over-year to $12.6 million, with an operating margin of 21% [15] - Fully diluted EPS rose to $0.48, up 10% [15] - Cash and securities at the end of Q1 2025 totaled $302.5 million, an increase of $2.8 million during the quarter [15] Business Line Data and Key Metrics Changes - Sales records were achieved in all five categories: grafts (up 17%), carotid shunts (up 14%), catheters, valvulotomes, and patches [5] - The autograft, a biologic graft, was the largest U.S. product in 2024 with $37 million in sales, and the European market size is estimated at $8 million [8][9] Market Data and Key Metrics Changes - By geography, EMEA sales increased by 18%, Americas by 11%, and APAC by 3% [5] - International sales of autografts reached $180,000 in Q1, with expectations for approvals in Australia, Canada, Singapore, and Korea by H1 2026 [9] Company Strategy and Development Direction - The company is focusing on expanding its sales force, targeting 170 representatives by year-end, up from 164 [6] - A new distribution facility in Dublin is planned to support pan-European distribution of RestoreFlow [11][106] - The company aims to improve organic growth and gross margin by winding down the porcine patch distribution agreement with Eulsha [16] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in increasing guidance due to strong Q1 performance, effective price increases, and the positive impact of new sales representatives [26][30] - The company anticipates that trade tensions will not significantly impact its operations due to its U.S.-only manufacturing footprint [19][20] Other Important Information - The company has raised its full-year revenue guidance to $245 million, reflecting robust sales performance and a weaker U.S. dollar [21] - The anticipated gross margin for the full year is now 69.6%, with operating income projected at $57.7 million [21] Q&A Session Summary Question: What gives confidence to increase guidance early in the year? - Management cited strong Q1 performance, better-than-expected price increases, and the positive impact of exiting the Aleutia business as key factors [26][30] Question: Any updates on M&A activity? - The pipeline is strong, focusing on open vascular surgery and adjacent cardiac surgery markets, with a preference for larger deals [33] Question: Concerns regarding XenoSure in China? - Management acknowledged challenges but remains committed to the market, expecting to continue pursuing provincial approvals [38] Question: Clarification on gross margin performance? - The allograft product's strong performance contributed to the gross margin miss, with expectations for improved margins in the second half of the year [60][62] Question: How will the sales force ramp-up impact operating leverage? - Management indicated that new sales representatives are expected to contribute to operating income growth, with a projected 14% increase in H2 [70] Question: Impact of tariffs on guidance? - Tariffs have been factored into guidance, with price increases planned to offset costs associated with tariffs [88] Question: How does exiting the Aleutia agreement impact organic growth? - Exiting the agreement is expected to improve organic growth as the product was declining in sales [91][92]