Financial Data and Key Metrics Changes - Revenues increased by 5% to $1.7 billion, EBITDA grew by 12% to $5.3 billion, EPS rose by 19% to $2.93, and free cash flow was up 16% to $2.4 billion [7][28][30] - Net debt to EBITDA ratio improved to 2.5 times, with a target of 2 times by 2027 [8][28] Business Line Data and Key Metrics Changes - Innovative portfolio showed strong growth: AUSTEDO grew by 34% to $2.26 billion, UZEDY increased by 63% to $191 million, and AJOVY rose by 30% to $673 million [9][10][12] - Generics business remained flat, with U.S. growth at 2%, international markets at 1%, and Europe declining by 2% [16][30] Market Data and Key Metrics Changes - The U.S. generics market faced challenges, particularly with the loss of revenue from generic Revlimid, expected to impact 2026 [34][37] - The biosimilars portfolio is expanding, with 10 assets currently in the market and plans to launch 6 additional by 2027 [18][30] Company Strategy and Development Direction - The company is focused on its "Pivot to Growth" strategy, emphasizing innovative products and a shift from generics to biopharma [4][28] - A target of $700 million in net savings by 2027 is set, with $70 million achieved in 2025 [29][33] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving long-term financial targets for 2030, with a focus on innovative growth and margin expansion [28][41] - The company anticipates a gradual revenue increase in 2026, despite challenges in the generics segment [34][39] Other Important Information - The company received a $500 million milestone payment from Sanofi, positively impacting revenue and free cash flow [30] - Non-GAAP gross margin increased to 56.2%, with expectations for 54.5%-55.5% in 2026 [31][35] Q&A Session Summary Question: Insights on AUSTEDO and UZEDY pricing dynamics - Management highlighted strong TRX growth for AUSTEDO and maintained a disciplined approach to pricing, expecting continued growth despite competitive pressures [50][51] - For UZEDY, management acknowledged the mix of Medicaid and Medicare affecting profitability but remained optimistic about continued momentum [53][54] Question: Pipeline excitement versus market perception - Management noted that the rapid development of the pipeline may have surprised investors, emphasizing the quality and potential of new products [57][60] Question: Funding R&D and economic implications of partnerships - Management stated that partnerships do not significantly impact economics, as new product launches enhance gross margins and EBITDA [65][66] Question: Expectations for TL1A maintenance data - Management expressed optimism about the upcoming maintenance data, citing the potency and selectivity of the product [70][71]

Financial Data and Key Metrics Changes - Revenues increased by 5% to $1.7 billion, EBITDA grew by 12% to $5.3 billion, EPS rose by 19% to $2.93, and free cash flow was up 16% to $2.4 billion [5][6][26] - Net debt to EBITDA ratio improved to 2.5 times, with a target of 2 times by 2027 [6][26] Business Line Data and Key Metrics Changes - Innovative portfolio showed strong growth: AUSTEDO grew by 34% to $2.26 billion, UZEDY increased by 63% to $191 million, and AJOVY rose by 30% to $673 million [7][8][12] - Generics business remained flat, with U.S. growth at 2%, international markets at 1%, and Europe declining by 2% [15] Market Data and Key Metrics Changes - The U.S. generics market faced challenges, particularly with the loss of generic Revlimid revenue, impacting overall revenue guidance for 2026 [33] - The innovative products are expected to drive growth, with Otezla, AJOVY, and UZEDY showing strong momentum [28][33] Company Strategy and Development Direction - The company is focused on its "Pivot to Growth" strategy, aiming for $700 million in net savings by 2027 and a 30% non-GAAP operating margin [4][26][31] - The pipeline includes multiple products with significant market potential, with a focus on addressing unmet medical needs [18][24] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving long-term financial targets for 2030, with a focus on innovative growth and transformation programs [26][40] - The company anticipates continued strong performance in its innovative portfolio, despite challenges in the generics market [33][34] Other Important Information - The company has made significant progress in its biosimilars portfolio, with plans to launch six additional assets by 2027 [15][16] - The innovative pipeline is expected to generate over $10 billion in peak sales potential [14] Q&A Session Summary Question: Insights on AUSTEDO and UZEDY pricing dynamics - Management highlighted strong TRX growth and maintained a disciplined approach to pricing, expecting continued growth despite competitive pressures [49][50][52] Question: Disconnect between pipeline excitement and market perception - Management noted that the rapid development of the innovative pipeline may have surprised investors, emphasizing the quality and potential of upcoming products [56][59] Question: Funding R&D and balancing partnerships - Management stated that partnerships do not significantly impact economics, as the innovative products are expected to enhance gross margins and EBITDA [65][66] Question: Expectations for TL1A maintenance data - Management expressed optimism about the upcoming maintenance data, citing the product's potency and selectivity as key factors for positive outcomes [70]

Teva Pharmaceutical Industries Ltd. This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, which are based on management's current beliefs and expectations and are subject to substantial risks and uncertainties, both known and unknown, that could cause our future results, performance or achievements to differ significantly from that expressed or implied by such forward-looking statements. Important factors that could cause or contrib ...

Cautionary Note Regarding Forward-Looking Statements This presentation contains forward -looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, which are based on management 's current beliefs and expectations and are subject to substantial risks and uncertainties, both known and unknown, that could cause our future results, performance or achievements to differ significant ly from that expressed or implied by such forward -looking statements. Important factors that c ...

Core Insights - Teva Pharmaceutical Industries Ltd. is set to present its ongoing transformation and growth trajectory through 2030 at the 44th Annual J.P. Morgan Healthcare Conference [1] - The presentation will highlight milestones achieved in 2025, transformative initiatives, and a forward-looking outlook for 2026 and beyond [1] Financial Performance Outlook - Expected revenues for 2025 are projected to be between $16.8 billion and $17.0 billion, with a lower point of the range contributing an additional $500 million from duvakitug milestones [3] - Operating margin is anticipated to be around 26.2% to 27.1%, with a mid to high point of the range contributing approximately 80%-85% [3] - Adjusted EBITDA is expected to be between $4.8 billion and $5.0 billion, with a midpoint of the range contributing around $400 million to $430 million [3] - The diluted EPS is projected to be between $2.55 and $2.65, with the higher point of the range being emphasized [3] - Free cash flow is expected to be between $1.6 billion and $1.9 billion, with a higher point of the range contributing approximately $500 million [3] - Net leverage is projected to be around 2.5x to 2.9x, with a midpoint of the range at approximately 2.5x [3] Future Growth Strategy - Teva is accelerating its "Pivot to Growth" strategy, focusing on becoming a leading innovative biopharmaceutical company, supported by its generics business [6] - Key innovative brands such as AUSTEDO, AJOVY, and UZEDY are driving growth and reshaping the financial outlook [6] - The clinical pipeline includes assets like olanzapine LAI, DARI, duvakitug, emrusolmin, and anti-IL-15, which are expected to support long-term growth [6] - For 2026, revenues are expected to be flat to slightly down compared to 2025, with low-single digit growth anticipated for 2027 and mid-single digit CAGR by 2030 [5] - Operating profit is expected to grow by 30% in 2027, with free cash flow projected to exceed $2.7 billion [5]

Core Insights - Teva Pharmaceutical Industries Limited has submitted a new drug application (NDA) to the FDA for olanzapine, a long-acting subcutaneous injectable for treating adults with schizophrenia [1][7] - The NDA is backed by phase III SOLARIS study data, demonstrating olanzapine LAI's efficacy, safety, and tolerability in adults aged 18 to 64 with schizophrenia [2][7] - If approved, olanzapine LAI could fill a significant treatment gap for schizophrenia patients, offering a once-monthly formulation [3][9] Teva's Market Performance - Year-to-date, Teva's shares have increased by 29.6%, outperforming the industry average rise of 27.9% [4] - Teva's existing product Uzedy, a long-acting subcutaneous atypical antipsychotic, has contributed significantly to revenue, with sales increasing by 82% year-over-year to $136 million in the first nine months of 2025 [8] Future Revenue Potential - Teva anticipates that its long-acting schizophrenia franchise, including Uzedy and olanzapine LAI, could generate peak sales of $1.5 to $2.0 billion [9] - The company expects to generate over $5 billion in revenues from its branded products by 2030 [12] Branded Drug Pipeline - Teva has seen growth in its branded drugs, with Austedo sales rising by 33% in the first nine months of 2025, and expectations for annual revenues to exceed $2.5 billion by 2027 [10] - The company is also advancing its pipeline with duvakitug, an anti-TL1A therapy for inflammatory bowel diseases, in partnership with Sanofi [11]

Q3 2025 Financial Performance - Revenues reached $4480 million, a 3% increase year-over-year[21, 93] - Adjusted EBITDA was $1400 million, up by 6% compared to the previous year[21] - Non-GAAP EPS increased by 14% to $078[21] - Free Cash Flow was $500 million[21] AUSTEDO Performance and Outlook - AUSTEDO U S revenues grew by 38% year-over-year to $601 million in Q3 2025[32] - AUSTEDO global revenues grew by 38% year-over-year to $618 million in Q3 2025[25] - The company reaffirmed its 2027 sales target for AUSTEDO at over $25 billion[29, 58] Pipeline and Strategic Updates - UZEDY revenues in Q3 2025 reached $43 million, a 24% increase year-over-year[25, 36] - The company reaffirmed its 2025 revenue outlook for UZEDY at $190 million - $200 million[35] - Global revenues for AJOVY reached $168 million in Q3 2025, a 19% increase year-over-year[25, 46] - The company is targeting olanzapine LAI FDA submission in Q4 2025[48, 63]

Financial Performance - Teva's Q2 2025 revenues remained flat at $4176 million compared to Q2 2024, but excluding Japan BV, revenues increased by 2%[87] - Non-GAAP EPS increased by 10% to $066 in Q2 2025 compared to $061 in Q2 2024[87] - Free cash flow increased significantly by 47% to $476 million in Q2 2025 from $324 million in Q2 2024[87] - The company is on track to achieve a 30% operating profit margin (OPM) by 2027 through its transformation program[85, 91] Product Performance - AUSTEDO U S revenues grew by 22% year-over-year to $495 million in Q2 2025[26] - UZEDY revenues increased significantly by 120% year-over-year to $54 million in Q2 2025[22, 31] - AJOVY global revenues increased by 31% year-over-year to $155 million in Q2 2025[22, 34] - Global generics revenues declined by 2%[22], and in local currency, global generics revenues decreased 5% vs Q2'24 including Japan BV[23] Pipeline and Strategy - The company expects to submit olanzapine LAI for U S NDA in Q4 2025[36, 55, 62] - Teva is targeting peak sales of $15-2 billion for the LAI franchise (UZEDY and olanzapine LAI)[102] - The company anticipates the start of Phase 3 trials for duvakitug in ulcerative colitis (UC) and Crohn's disease (CD) by Sanofi in Q4 2025[68] - Teva transformation in '25 well on track to deliver annualized ~20% of total $700 million savings[105]

Teva Pharmaceutical Industries (TEVA) 2025 Conference Summary Company Overview - Teva Pharmaceutical Industries is focusing on a growth strategy initiated in 2023, emphasizing innovative medicines, pipeline advancements, generics, and business focus [2][3] Key Business Developments - Teva has experienced nine consecutive quarters of growth and is entering a new acceleration phase from 2025 to 2027 [3] - Key commercial assets include AUSTEDO, Yuzetti, and AJOVY, which are significant drivers for the company [3] AUSTEDO Insights - AUSTEDO is projected to achieve peak sales of over $3 billion, driven by an unmet need in the treatment of tardive dyskinesia (TD) [6][7] - Approximately 800,000 patients in the U.S. have TD, with only 15% diagnosed and 5-6% currently treated, indicating a substantial market opportunity [7] - AUSTEDO has seen 40% growth and 23% increase in total prescriptions (TRxs) [7] - Teva has invested in direct-to-consumer marketing to raise awareness and has filed for approval in Europe [8] Competitive Landscape - Teva views the competition with Neurocrine's INGREZZA as a collaborative effort to increase patient treatment rather than direct competition [9] - AUSTEDO maintains broad coverage, with patients paying an average of less than $10 out of pocket [10] Long-Acting Injectable (LAI) Developments - Teva is excited about the EZEDI long-acting injectable, which offers significant advantages for patient compliance and rapid relief [15][16] - The company aims to capture market share from existing LAIs like risperidone and paliperidone [16][19] - The long-acting olanzapine is expected to have a favorable launch trajectory, potentially faster than Yuzetti due to pent-up demand [20][21] TL1A Pipeline - TL1A is a promising new biologic targeting inflammatory pathways, with potential applications in ulcerative colitis and Crohn's disease [35][36] - The molecule has shown high efficacy in Phase II studies, with low rates of anti-drug antibodies [37][38] - Upcoming data updates are expected in the first half of 2026, focusing on maintenance data [40][41] DARE Program - The Dual Action Rescue Inhaler (DARE) targets the significant unmet need in asthma exacerbations, with a focus on combination therapies [57][58] - Teva is conducting the largest asthma study to date, aiming for broad labeling that includes pediatric populations [59][60] Market and Regulatory Considerations - Teva is actively managing tariff exposure, with a strong manufacturing presence in the U.S. and limited exposure to China and India [65][66] - The company has taken proactive measures to ensure inventory levels are sufficient to navigate potential market disruptions [67] Conclusion - Teva is positioned for growth with a robust pipeline and strategic focus on innovative therapies, while navigating competitive and regulatory landscapes effectively. The company remains committed to addressing significant unmet medical needs across its product offerings.

Growth Strategy - Teva aims to achieve a ~30% innovative franchise CAGR, targeting >$2.3 billion, and return generics powerhouse to +5% p a growth[22] - The company projects AUSTEDO sales to exceed $2.5 billion by 2027[52], and peak sales of >$3 billion[47] - Teva anticipates peak sales of $1.5-2 billion from its LAI (Long Acting Injectables) franchise, including UZEDY and olanzapine LAI[52] Financial Performance & Targets - The company is targeting a mid-single digit percentage revenue growth (CAGR '22 – '27)[44] and an operating income margin of 30%[44] - Teva aims to reduce net leverage to 20x[22,44] and increase free cash flow to >$27 billion by 2027[22,235] - The company plans to achieve ~$700 million in net savings by 2027 through transformation programs[220,225] Pipeline & Innovation - Olanzapine LAI is projected to have peak sales potential of >$15 – 20 billion, with targeted submission in H2 2025[38] - Duvakitug has a peak sales potential of ~$2-5 billion, with a targeted submission around 2029+[38] - Emrusolmin is projected to have peak sales potential of >$2 billion, with a targeted submission around 2031[38]