Teva Pharmaceutical Industries Conference Summary Company Overview - **Company**: Teva Pharmaceutical Industries (NYSE: TEVA) - **Event**: UBS Global Healthcare Conference - **Date**: November 10, 2025 Key Highlights Industry and Company Strategy - Teva has implemented a "pivot to growth" strategy over the past three years, focusing on three phases: return to growth, accelerate growth, and maintain growth [3][4] - The company has achieved its 11th consecutive quarter of growth in Q3 2025, marking a significant turnaround after years of decline [3][4] Financial Performance - Innovative business sales exceeded $800 million in Q3 2025, representing a 33% increase year-over-year [4] - Specific product growth rates in Q3 2025: - Austedo: up 38% - Ajovy: up 19% - UZEDY: up 24% [4] - Gross margin improved from 48% in Q1 2023 to a projected range of 40%-55% due to efficiency drives and a shift in product portfolio [4][5] Product Development and Pipeline - Teva is transitioning from a generics-focused company to a biopharma company with a strong innovative portfolio [6] - Upcoming product launches include: - Olanzapine (expected launch in the second half of 2026) [38] - Duvakitug (phase three trials for ulcerative colitis and Crohn's disease) [39] - DARI (dual action rescue inhaler) with a planned market entry in 2027 [43] Market Dynamics and Competitive Landscape - Teva is focusing on increasing patient access to its products, particularly in the Austedo market, where 85% of patients are untreated [11][12] - The company is cautious about pricing strategies, maintaining discipline to avoid discounting unless necessary [30] - Teva is preparing for a more challenging payer market, emphasizing the importance of balancing value and access [12][13] Long-term Financial Guidance - Teva reiterated its 2027 revenue guidance of $2.5 billion to $3 billion for Austedo and $1.5 billion to $2 billion for its schizophrenia franchise [32][55] - The company aims for mid-single-digit compound annual growth rate (CAGR) in revenue despite the anticipated loss of Revlimid in 2026 [55] Capital Allocation and Strategic Decisions - Teva is reassessing its non-core assets, including the TAPI API business, to ensure alignment with its long-term biopharma strategy [57][58] - The company is committed to thoughtful capital allocation, focusing on investments that drive long-term value [19][61] Biosimilars and Generics - Teva is expanding its biosimilars portfolio through partnerships, aiming for over 30 biosimilars in the market [46] - The company views recent FDA simplifications in clinical trial requirements positively, believing it will not lead to a significant influx of competitors due to the high technical and financial barriers [45][46] Additional Insights - Teva's OTC business is seen as synergistic with its generics and innovative products, contributing to overall growth [60][61] - The company emphasizes the importance of understanding the patient journey and optimizing treatment pathways to enhance product uptake [9][36] This summary encapsulates the key points discussed during the conference, highlighting Teva's strategic direction, financial performance, product pipeline, and market positioning.

Core Insights - Teva Pharmaceutical Industries Ltd. reported third-quarter earnings that exceeded expectations, driven by strong sales of innovative therapies and an improved full-year outlook, resulting in a share price surge of over 17% in intra-day trading [1] Financial Performance - The company posted adjusted earnings of $0.78 per share, surpassing analyst forecasts of $0.68 [1] - Revenue increased by 3% year over year to $4.48 billion, exceeding the consensus estimate of $4.36 billion, with 1% growth in local currency [1] Innovative Medicine Portfolio - Teva's innovative medicine portfolio, including AUSTEDO, AJOVY, and UZEDY, saw segment revenue rise by 33% year over year in local currency to $830 million [2] - AUSTEDO was the primary driver of growth, achieving $618 million in global sales, reflecting a 38% increase in local currency [2] Future Outlook - Based on strong momentum, Teva raised its 2025 AUSTEDO revenue forecast by $50 million to $100 million, establishing a new target range of $2.05 billion to $2.15 billion [3] - The company tightened its full-year revenue guidance to a range of $16.8 billion to $17.0 billion and raised the low end of its adjusted EPS range to $2.55–$2.65 from $2.50–$2.65 [3] Operational Efficiency - Teva's non-GAAP operating margin improved to 28.9%, an increase of 86 basis points from the previous year, keeping the company on track to achieve its 30% target by 2027 under its "Pivot to Growth" strategy [4]

Financial Data and Key Metrics Changes - Teva reported Q3 2025 revenue of approximately $4.5 billion, representing a 3% increase compared to Q3 2024 [4][28] - Adjusted EBITDA increased by 6%, and non-GAAP EPS rose by 14% year over year [4][30] - Free cash flow for Q3 was $515 million, down from $922 million in Q3 2024, primarily due to timing of sales and higher legal settlement payments [30] - Net debt to EBITDA ratio improved to below three times for the first time since 2016, with expectations to reach around 2.8 by the end of the year [4][18] Business Line Data and Key Metrics Changes - Innovative products generated over $800 million in revenue for the quarter, growing 33% year on year [5] - Austedo revenue reached $618 million, up 38% year over year [5][7] - UZEDY revenues increased by 24% to $43 million, with TRx up 119% [9] - Ajovy grew 19% to $168 million [11] - Global generics revenues increased by 2%, while TAPI declined by 4% due to seasonal volatility [6][14] Market Data and Key Metrics Changes - US generics business grew by 7% in Q3, driven by strong performance in biosimilars and several launches [14] - European generics declined by 5% due to tough comparisons from the previous year [14] - International markets grew at 3%, or 12% on a two-year CAGR [14] Company Strategy and Development Direction - Teva's strategy focuses on four pillars: delivering growth engines, stepping up innovation, sustaining generics, and focusing the business [3] - The company aims for mid-single-digit growth by 2027, with a target of $2.5 billion in revenue for Austedo by that year [6][27] - Teva is on track to achieve approximately $700 million in net savings by 2027 through transformation programs [31][27] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in achieving 2025 growth targets of 3%-4% and reiterated the 2027 revenue targets [18][27] - The company highlighted the significant unmet need in treating tardive dyskinesia, which supports the growth potential for Austedo [42] - Management remains optimistic about the innovative pipeline and the potential for future growth drivers [13][39] Other Important Information - Teva is initiating a renewed sale process for TAPI after previous discussions did not align with long-term priorities [32] - The company is focused on maintaining a disciplined capital allocation approach while reducing debt and investing in growth [37] Q&A Session Summary Question: Insights on Austedo and IRA negotiations - Management confirmed that the negotiated price for Austedo was in line with internal expectations, supporting confidence in achieving $2.5 billion in revenue [41][42] Question: Pricing structure of Austedo XR and access implications - Management emphasized that Austedo's growth is driven by addressing an underserved market and maintaining access while managing pricing effectively [44][46] Question: OpEx expectations for 2026 - Management indicated that the majority of cost savings from the transformation program will impact OpEx, maintaining a range of 27%-28% [47][49] Question: EU generics market dynamics - Management noted that the EU generics business is expected to grow at a 2% CAGR, with future growth driven by biosimilars [50][52] Question: TAPI divestment process - Management explained that TAPI is considered strategic for sourcing API, leading to the decision to restart the sales process [54][55]

Q3 2025 Financial Performance - Revenues reached $4480 million, a 3% increase year-over-year[21, 93] - Adjusted EBITDA was $1400 million, up by 6% compared to the previous year[21] - Non-GAAP EPS increased by 14% to $078[21] - Free Cash Flow was $500 million[21] AUSTEDO Performance and Outlook - AUSTEDO U S revenues grew by 38% year-over-year to $601 million in Q3 2025[32] - AUSTEDO global revenues grew by 38% year-over-year to $618 million in Q3 2025[25] - The company reaffirmed its 2027 sales target for AUSTEDO at over $25 billion[29, 58] Pipeline and Strategic Updates - UZEDY revenues in Q3 2025 reached $43 million, a 24% increase year-over-year[25, 36] - The company reaffirmed its 2025 revenue outlook for UZEDY at $190 million - $200 million[35] - Global revenues for AJOVY reached $168 million in Q3 2025, a 19% increase year-over-year[25, 46] - The company is targeting olanzapine LAI FDA submission in Q4 2025[48, 63]

For an accessible version of this Press Release, please visit www.tevapharm.com Teva reports revenues of $4.5 billion in the third quarter of 2025, an increase of 3% year-over-year (YoY) in U.S. dollars or 1% in local currency (LC). Excluding Japan BV in Q3 2024, revenues increased 5% in U.S. dollars or 3% in LC. United States segment increased by 12%; Europe segment decreased by 10% in LC; and International Markets segment decreased by 10% in LC, or increased by 2% in LC excluding Japan BV in Q3 2024, all ...

Core Thesis - Teva Pharmaceutical Industries Limited is transitioning from a debt-laden generics company to a focused branded and specialty firm, with significant momentum in neuroscience and a bullish outlook from institutional investors [2][6]. Financial Performance - Teva's projected revenues for 2025 are near $17 billion, with earnings per share (EPS) around $2.60 and EBIT margins approaching 27%. The company has reduced net debt from over $18 billion to approximately $11 billion, with expectations for further deleveraging [5]. Product Pipeline - Ajovy, Teva's anti-CGRP therapy for migraine prevention, is expected to generate quarterly sales of around $70 million, establishing a strong presence in the expanding migraine market [3]. - The long-acting injectable olanzapine program, TEV-749, has shown robust efficacy in Phase 3 trials and could potentially generate peak sales of $1.5–2.0 billion, reshaping Teva's psychiatry franchise [4]. Market Positioning - Teva's stock has recovered past $20, holding above key moving averages, indicating a constructive technical setup. The convergence of pipeline progress, technical strength, and improving fundamentals positions the stock for a potential re-rating [2][6]. Historical Context - Since a previous bullish thesis in May 2025, Teva's stock price has appreciated approximately 20%, with ongoing momentum in neuroscience and emphasis on TEV-749 as a new catalyst [7].

Core Insights - Teva Pharmaceutical Industries Limited has received FDA approval for an expanded indication of UZEDY for the maintenance treatment of bipolar I disorder (BD-I) in adults [1][3] - UZEDY is a long-acting formulation of risperidone that utilizes proprietary technology to control the steady release of the medication, reaching therapeutic blood concentrations within 6-24 hours [2] Product Details - UZEDY is now approved with three once-monthly dosing options: 50 mg, 75 mg, and 100 mg for the newly approved BD-I indication [3] - The drug was previously approved for the treatment of schizophrenia in adults, with dosing options available every one or two months [3] Market Context - BD-I affects an estimated 1% of US adults, translating to over 3.4 million individuals, highlighting the significant unmet needs in this patient population [2] - Teva operates in the development, manufacturing, marketing, and distribution of generic and biopharmaceutical products across various regions including the US, Europe, and Israel [4]

Core Insights - Teva Pharmaceutical Industries Limited is recognized as a promising stock under $100, with BofA raising its price target to $24 from $22 while maintaining a Buy rating [1] - The company has achieved its 10th consecutive quarter of year-over-year revenue growth, driven by its Pivot to Growth Strategy, targeting a 30% operating profit margin by 2027 [2] - Teva's innovative product portfolio has seen significant growth, with total revenues for Q2 2025 reaching $4.2 billion, marking a ~1% increase in local currency [2][3] Financial Performance - Teva's innovative portfolio collectively grew by ~26%, leading to an increased revenue outlook for key products [3] - AUSTEDO revenues were $498 million globally in Q2, up ~19% globally and ~22% in the US, with the 2025 revenue outlook raised to $2,000 to $2,050 million [3] - AJOVY global revenues reached $155 million, up ~31%, with the outlook increased to $630 to $640 million [3] - UZEDY revenues accelerated by ~120% to $54 million, with the outlook raised to $190 to $200 million [3] Strategic Initiatives - Teva is executing its Pivot to Growth Strategy, which has been a key driver of its recent revenue growth [2][3] - The company is focused on achieving a 30% operating profit margin by 2027 as part of its long-term strategy [2]

Teva's Pipeline and Capabilities - Teva has in-house R&D experts with a proven track record in developing neuroscience products at all stages of development[15] - Teva has substantial, experienced commercial neuroscience teams[16] Schizophrenia Market and Unmet Needs - There are an estimated ~47 million prevalent schizophrenia patients in the US and Europe[35] - Approximately 23 million patients are diagnosed, and ~21 million are treated[39] - Long untreated psychosis is associated with poor long-term outcomes[21] - Suboptimal medication adherence is a major modifiable risk factor for relapse, highlighting the need for LAIs[22] Teva's Olanzapine LAI (TEV-'749) - Teva's olanzapine LAI met primary and key secondary efficacy endpoints at all 3 doses[30] - The efficacy and systemic safety profile of Teva's olanzapine LAI is comparable to daily oral olanzapine, with no PDSS to date[30] - Approximately 4,000 subcutaneous injections across multiple clinical studies, with no PDSS observed[30] - All TEV-'749 doses exhibited long-term, continuous symptom improvement and maintenance of clinical effectiveness in the SOLARIS study[59] - No suspected or confirmed PDSS events were reported in 3470 injections[59] Commercial Opportunity - Teva aims to be the preferred LAI for patients appropriate for oral risperidone or paliperidone and modestly controlled patients seeking additional convenience[34] - Teva is addressing a broad spectrum of patients with UZEDY and olanzapine LAI, with 65%-80% of patients having the potential to switch as they are currently on a similar molecule[45] - Teva anticipates franchise peak sales expectation of $15 billion-$20 billion for Olanzapine LAI TEV-'749[45]

Core Insights - Teva Pharmaceuticals presented new data on its schizophrenia treatment portfolio, including long-term safety results from the SOLARIS Phase 3 trial for olanzapine LAI (TEV-'749), which showed no incidence of post-injection delirium/sedation syndrome (PDSS) [1][4] - The data also highlighted UZEDY, an extended-release injectable suspension of risperidone, which was associated with shorter hospitalization compared to Invega Sustenna, although no direct comparisons on efficacy or safety were made [1][9] Olanzapine LAI (TEV-'749) Data - The SOLARIS trial involved 675 participants aged 18-64, with a randomized double-blind placebo-controlled period followed by an open-label safety period [3][17] - No PDSS events were reported across 3,470 total injections, indicating a favorable safety profile consistent with other olanzapine formulations [4][5] - Long-term effectiveness data showed significant symptom improvement, with a mean change of -7.2 in PANSS total scores and a 4.6-point increase in PSP scores from baseline [7][8] UZEDY Data - A retrospective study indicated that UZEDY led to a 2.89-day shorter length of hospital stay compared to Invega Sustenna, translating to estimated direct cost savings of $3,200 per hospitalization [9] - UZEDY was preferred by healthcare professionals for its ease of administration and dosing characteristics, with 45% favoring it over Invega Sustenna [9][10] Company Commitment - Teva is dedicated to developing innovative treatments for complex neurological conditions, aiming to address unmet needs in mental health care [5][14] - The company plans to submit a New Drug Application (NDA) for olanzapine LAI (TEV-'749) in the second half of 2025 [13][15]