Accessibility StatementSkip Navigation ROM, 15. November 2025 /PRNewswire/ -- Fondazione Telethon gibt die positive Stellungnahme des Ausschusses für Humanarzneimittel (CHMP) der Europäischen Arzneimittelagentur (EMA) bekannt, in der die Zulassung von Waskyra™ in der Europäischen Union empfohlen wird, einer ex-vivo -Gentherapie für das Wiskott-Aldrich-Syndrom (WAS), eine seltene und lebensbedrohliche primäre Immundefizienz. Die Fondazione Telethon ist die erste gemeinnützige Organisation, die den gesa ...

Core Points - The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) has issued a positive opinion recommending the market authorization of Waskyra™, a gene therapy for Wiskott-Aldrich Syndrome (WAS) [1][12][13] - The therapy was developed over decades at the San Raffaele Telethon Institute for Gene Therapy (SR-Tiget) in Milan, representing a significant scientific and clinical advancement [3][4] - Waskyra™ offers new hope for patients suffering from WAS, a rare genetic blood disorder that leads to immunodeficiency and low platelet counts [7][9] Company Overview - Fondazione Telethon is the first non-profit organization to successfully navigate the entire process from laboratory research to regulatory approval, collaborating with industrial partners when necessary [2][4] - The organization has been dedicated to advancing research on rare genetic diseases for over 35 years, supporting impactful scientific work aimed at developing innovative treatments [11] Therapy Details - Waskyra™ involves a single administration of autologous CD34+ hematopoietic stem and progenitor cells that have been modified with a lentiviral vector carrying the WAS gene [9][10] - The therapy has shown to reduce the frequency of severe and moderate bleeding events and serious infections in patients with WAS compared to the pre-treatment period [10] - The therapy will be available to patients at the IRCCS Ospedale San Raffaele, a recognized center of excellence for gene therapy [5]

Core Insights - The eosera® Foundation Pitch Competition awarded Cherie Turner, CEO and Founder of Mommy Scrubs, a total of $35,000, including a $30,000 first place award and a $5,000 people's choice award, highlighting the support for women entrepreneurs in the healthcare sector [2][3][9]. Company Highlights - Mommy Scrubs, founded by Cherie Turner, focuses on designing postpartum scrubs specifically for breastfeeding mothers in healthcare, addressing the challenges faced by these professionals [7][8]. - The company has developed a patent-pending design that allows for easy pumping access while maintaining the functionality of standard scrubs, indicating a strong market need and innovative approach [8]. Industry Context - The competition, hosted by the eosera® Foundation, received over 250 applications, showcasing the growing interest and participation of women entrepreneurs in the business landscape [3][4]. - Fort Worth is recognized as the second fastest-growing area for women-owned businesses in the U.S., reflecting a positive trend in female entrepreneurship [4]. - The event emphasized the importance of supporting small businesses and entrepreneurs as a foundation for economic growth, aligning with broader trends in investment and community support for women-led initiatives [5][12].

Company Overview - Netflix, Inc. provides entertainment services with over 300 million paid memberships across more than 190 countries [2]. Investigation Details - Robbins Geller Rudman & Dowd LLP is investigating potential violations of U.S. federal securities laws involving Netflix and its executives for making materially false and/or misleading statements or omitting material information regarding the company's business and operations [1][2].

Core Insights - The Nobel Sustainability Trust (NST) commended Qatar for its leadership in sustainability and innovation, highlighting the nation's commitment to creating a sustainable future and inspiring global movements towards responsible growth [1][4][8] Group 1: Qatar's Achievements in Sustainability - Qatar's leadership is characterized by a strategic approach that integrates sustainability into all layers of national development, as emphasized by H.E. Abdullah bin Hamad Al Attiya, Minister of Municipality and Chairman of Qatari Diar [2] - NST delegates witnessed groundbreaking sustainability initiatives during their visit, reinforcing Qatar's position as a leader in environmental responsibility and sustainable advancement [3] Group 2: Statements from NST Leadership - Peter Nobel, Chairman of NST, described Qatar's achievements as inspirational and transformative, noting that the nation is redefining leadership with vision, purpose, and responsibility [4] - Tracy Wang, CEO of NST, remarked on the spirit of collaboration and innovation in Qatar, indicating that the nation is building a legacy of progress that will serve as a global benchmark for sustainable transformation [4] Group 3: NST's Commitment - The Nobel Sustainability Trust reaffirmed its commitment to showcasing Qatar's accomplishments on the world stage, recognizing the nation as a leading force in sustainable development and innovation [4][5]

Core Insights - The Nobel Sustainability Trust (NST) commended Qatar for its remarkable achievements and visionary approach in sustainability, innovation, and environmental responsibility [1][4] - Qatar's leadership is characterized by a commitment to sustainable development that integrates innovative practices across various sectors [2][4] - NST aims to showcase Qatar's accomplishments on a global stage, recognizing the nation as a leading force in sustainable development and innovation [4][5] Group 1 - NST delegation was deeply impressed by Qatar's unwavering commitment to a sustainable future, promoting responsible growth and a better world for future generations [1][3] - S.E. Abdullah bin Hamad Al Attiya highlighted Qatar's strategic approach and its efforts to challenge conventional thinking while integrating sustainability into national development [2][4] - The NST visit included presentations on groundbreaking sustainability initiatives, reinforcing Qatar's position as a pioneer in environmental responsibility [3][4] Group 2 - Peter Nobel described Qatar's achievements in sustainability as inspiring and transformative, emphasizing the nation's leadership and collective pride in these accomplishments [4] - Tracy Wang noted the spirit of collaboration and innovation in Qatar, indicating that the country sets a global benchmark for sustainable transformation [4] - The Nobel Sustainability Trust, founded by members of the Nobel family, promotes global initiatives that advance sustainable innovations and responsible development [5]

Core Insights - The Nobel Sustainability Trust (NST) commended Qatar for its remarkable achievements and future vision in sustainability, innovation, and environmental management during a recent visit to Doha [1][4][6] - Qatar's unwavering commitment to creating a sustainable future is highlighted, aiming to protect the environment and inspire global movements towards responsible growth [1][4] - The NST delegation observed revolutionary sustainability initiatives in Qatar, reinforcing the country's position as a model of environmental responsibility and sustainable development [3][4] Strategic Approach - S.E. Abdullah bin Hamad Al Attiya, Minister of Municipality and President of Qatari Diar, shared insights on Qatar's strategic approach and its determination to remain at the forefront of progress [2] - Qatar's leaders are noted for challenging conventional ideas, innovating across sectors, and integrating sustainability into all levels of national development [2] Inspirational Leadership - Peter Nobel, Chairman of NST, described Qatar's efforts in sustainability as inspirational and transformative, emphasizing the nation's leadership with vision, purpose, and responsibility [4] - Tracy Wang, CEO of NST, remarked on the spirit of collaboration and innovation in Qatar, viewing it as a model for global sustainable transformation [5] Global Recognition - The NST reaffirmed its commitment to showcasing Qatar's achievements on the global stage, recognizing the nation as a leading force in sustainable development and innovation [6]

Core Insights - Pullman Hotels & Resorts has announced a global brand transformation aimed at positioning its hotels as vibrant places of exchange, following the successful launch of Pullman xChange in Dubai [1][2][13] Brand Transformation - The transformation redefines the hotel experience, focusing on creating dynamic social spaces that reflect the modern traveler's needs [2][13] - The Pullman Portal, inspired by historical railway tunnels, serves as a new architectural signature for the brand, with installations planned across various locations [3][14] Meeting and Event Spaces - Meeting and event spaces have been redesigned for flexibility, allowing for easy transformation to suit various functions, promoting an environment conducive to exchange [4][13] Culinary Experience - Culinary offerings will emphasize spontaneity and shareability, with bars becoming central social hubs [5][13] - An experiential bar ritual called Unexpected Pairings will launch in 2026, encouraging guests to explore unique food and cocktail combinations [6][13] Service Culture - A new training program focused on empathy and cultural awareness has been introduced for staff, with around 60% of the workforce already trained [7][8] - The service culture aims to enhance guest interactions through emotional intelligence and genuine care [7][8] Pullman xChange Event - The inaugural Pullman xChange event took place in November 2025, fostering creative dialogue and collaboration among leaders and innovators [9][10] - Future editions of Pullman xChange will occur in Europe, Asia, and South America, co-created with local cultural collectives [12][13] Growth Momentum - Pullman aims to expand its global presence, with over 150 hotels in more than 40 countries and plans to exceed 200 hotels within five years [14][15] - New properties, including Pullman Royal Key Wellness Resort and Pullman Tokyo Ginza, will showcase the brand's commitment to innovative design and cultural exchange [15][14]

Core Viewpoint - Colombia has initiated a cash tender offer to purchase outstanding bonds, with the maximum purchase amount to be determined at the government's discretion, subject to financing conditions [1][2]. Offer Details - The offer is not contingent on any minimum participation from holders of the old bonds [2]. - The purchase price for each series of bonds will be fixed, with additional accrued interest paid to holders whose bonds are accepted [3][10]. - If the total purchase price exceeds the maximum purchase amount, a proration factor will be applied [3]. Old Bonds Information - The outstanding principal amounts and fixed purchase prices for various series of old bonds are detailed, including: - 3.875% Global Bonds due 2026: €634.89 million, Purchase Price: €1,005.71 - 9.850% Global TES Bonds due 2027: Ps. 1,924.52 billion, Purchase Price: Ps. 1,000.00 - 3.875% Global Bonds due 2027: $1.74 billion, Purchase Price: $1,000.00 - 4.500% Global Bonds due 2029: $2.00 billion, Purchase Price: $1,000.00 - 3.000% Global Bonds due 2030: $1.54 billion, Purchase Price: $918.75 - 7.375% Global Bonds due 2030: $1.90 billion, Purchase Price: $1,086.25 - 10.375% Global Bonds due 2033: $340.51 million, Purchase Price: $1,277.50 - 8.000% Global Bonds due 2033: $1.62 billion, Purchase Price: $1,127.50 - 7.500% Global Bonds due 2034: $2.20 billion, Purchase Price: $1,087.50 - 8.500% Global Bonds due 2035: $1.90 billion, Purchase Price: $1,160.00 - 8.000% Global Bonds due 2035: $1.90 billion, Purchase Price: $1,117.50 - 7.750% Global Bonds due 2036: $2.00 billion, Purchase Price: $1,090.00 - 7.375% Global Bonds due 2037: $1.82 billion, Purchase Price: $1,066.25 - 6.125% Global Bonds due 2041: $2.50 billion, Purchase Price: $928.75 - 5.000% Global Bonds due 2045: $3.67 billion, Purchase Price: $787.50 - 8.750% Global Bonds due 2053: $1.90 billion, Purchase Price: $1,192.50 - 8.375% Global Bonds due 2054: $1.64 billion, Purchase Price: $1,147.50 [4][5]. Tender Process - The tender offer commenced on November 14, 2025, and will expire on November 19, 2025, for U.S. Dollar Bonds and November 21, 2025, for Non-U.S. Dollar Bonds [11]. - Settlement is scheduled for November 26, 2025 [11]. - Old Bonds can only be tendered in minimum authorized denominations, with specific amounts outlined for each series [8][9]. Currency and Payment - Payments for the COP 2027 Global Bonds will be made in U.S. dollars, converted at the representative market rate prior to the expiration of the tender period [6][7]. - Holders must consult with their intermediaries regarding submission deadlines, which may differ from the official deadlines [12]. Additional Information - Global Bondholder Services Corporation is acting as the tender and information agent for the offer [14]. - The dealer managers for the offer include Santander U.S. Capital Markets LLC, Goldman Sachs & Co., and J.P. Morgan Securities LLC [15][16].

Core Points - Stride, Inc. is facing a securities class action lawsuit for failing to disclose material information during the class period from October 22, 2024, to October 28, 2025 [1][3] - The lawsuit is pending in the United States District Court for the Eastern District of Virginia, and investors have until January 12, 2026, to file lead plaintiff applications [1][6] Company Issues - On September 14, 2025, Gallup-McKinley County Schools Board of Education filed a complaint against Stride, alleging fraud and deceptive trade practices, including inflating enrollment numbers by retaining "ghost students" [4] - Following this news, Stride's share price dropped by $18.60, or 11.7%, closing at $139.76 on September 15, 2025 [4] - On October 28, 2025, Stride disclosed that "poor customer experience" led to higher withdrawal rates and lower conversion rates, resulting in an estimated 10,000-15,000 fewer enrollments, which negatively impacted the company's outlook [5] - This announcement caused Stride's share price to plummet by $83.48, or over 54%, closing at $70.05 on October 29, 2025 [5]