Core Viewpoint - Incyte Corporation (INCY) is expected to exceed expectations in its second-quarter 2024 results, scheduled for release on July 30, before the market opens [1] Revenue Sources - Incyte primarily generates product revenues from its lead drug, Jakafi (ruxolitinib), in the United States and other marketed drugs [2] - The company earns product royalty revenues from Novartis AG (NVS) for the commercialization of Jakafi in markets outside the U.S. [3] - Incyte also receives royalties from Tabrecta (capmatinib), which is approved for treating metastatic non-small cell lung cancer, with Novartis holding exclusive worldwide rights for its development and commercialization [4] Sales Estimates - The Zacks Consensus Estimate for Jakafi's sales in Q2 2024 is projected at $673 million [7] - Opzelura sales are estimated at $112 million for the same quarter, driven by increasing patient demand and payer coverage [5] - Sales estimates for other drugs include Iclusig at $30.12 million, Minjuvi at $27.49 million, and Pemazyre at $20.62 million [23] Recent Developments - In February 2024, Incyte entered into an asset purchase agreement with MorphoSys AG, acquiring exclusive global rights for tafasitamab, marketed as Monjuvi in the U.S. and Minjuvi outside the country [10] - Incremental sales from newly approved drugs like Opzelura and Zynyz are expected to contribute positively to Incyte's revenues in the upcoming quarter [22] Earnings Performance - Incyte has a mixed earnings surprise history, beating estimates in two of the last four quarters and missing in the other two, with an average negative earnings surprise of 6.24% [12] - The company's Earnings ESP is +7.41%, with the most accurate estimate at $1.25 compared to the Zacks Consensus Estimate of $1.16 [24] Market Performance - Incyte's shares have increased by 4.8% year-to-date, contrasting with a 2% decline in the industry [21] - The company is expected to benefit from higher royalties from Novartis due to increased Jakavi sales in international markets [20]

Incyte (INCY) is expected to deliver a year-over-year increase in earnings on higher revenues when it reports results for the quarter ended June 2024. This widely-known consensus outlook gives a good sense of the company's earnings picture, but how the actual results compare to these estimates is a powerful factor that could impact its near-term stock price. This specialty drugmaker is expected to post quarterly earnings of $1.16 per share in its upcoming report, which represents a year-over-year change of ...

Right now, Incyte is sporting a Zacks Rank of #2 (Buy), while Myriad Genetics has a Zacks Rank of #3 (Hold). This system places an emphasis on companies that have seen positive earnings estimate revisions, so investors should feel comfortable knowing that INCY is likely seeing its earnings outlook improve to a greater extent. But this is just one piece of the puzzle for value investors. INCY currently has a forward P/E ratio of 14.82, while MYGN has a forward P/E of 824.48. We also note that INCY has a PEG ...

Shares of Incyte (INCY) were on the upward trajectory in the past three months. The stock has risen 19.6% in this time frame compared with the industry's growth of 8.9%. Last week, Incyte announced that it granted restricted stock unit awards (RSUs), representing an aggregate of 14,577 shares of the company's common stock, and stock option awards to purchase an aggregate of 18,149 shares of the company's common stock to 27 new employees. The company's shares rose following this announcement. Image Source: Z ...

Core Insights - The acquisition of Escient Pharmaceuticals has significantly enhanced Incyte's portfolio of experimental drugs targeting inflammatory diseases, including chronic spontaneous urticaria and atopic dermatitis [1] - Incyte's FDA-approved medications, particularly Opzelura, are considered gold standards for treating conditions like myelofibrosis and vitiligo, with Opzelura showing strong demand and sales growth [2][4] Financial Performance - Incyte reported total sales of approximately $85.7 million in Q1 2024, reflecting a year-over-year increase of 51.4%, driven by high demand for Opzelura in the U.S. and its recent distribution in France [4] - The company's revenue for the first three months of 2024 was about $881 million, slightly missing analysts' expectations by $44 million, attributed to a decline in Jakafi sales [22] - Jakafi's net product revenues were $572 million in Q1 2024, down $8.2 million from the previous year due to increased competition [36] Product Pipeline and Development - Opzelura, containing ruxolitinib, is effective in treating autoimmune disorders by regulating the JAK-STAT signaling pathway, which is crucial for immune response [3] - The company is conducting clinical trials for Opzelura in various conditions, including atopic dermatitis in children aged 2 to 12, with expectations of total sales reaching $1.91 billion by 2027 [9][14] - Axatilimab, another promising drug, is under FDA Priority Review for chronic graft-versus-host disease, with a high overall response rate of 74% in clinical trials [38] Market Position and Future Outlook - Incyte's strong financial position, with cash and short-term investments exceeding $3.85 billion, supports its aggressive R&D strategy and potential partnerships [40] - The company is expected to see continued growth in sales due to its robust portfolio of experimental drugs and the anticipated approval of axatilimab [25][38] - Incyte's P/E ratio is currently lower than many competitors, indicating potential for stock price appreciation as the company progresses with its drug development and market strategies [46]

Core Insights - The report titled "Malignant Mesothelioma - Pipeline Insight, 2024" highlights the ongoing research and development efforts aimed at addressing the challenges posed by malignant mesothelioma, a rare but aggressive cancer linked to asbestos exposure [4][5][8] - A significant number of pharmaceutical companies are involved in developing innovative treatments, with over 20 drugs currently in various stages of clinical trials [8] Company and Industry Developments - Key players in the therapeutic landscape include Polaris Pharmaceuticals, Incyte Corporation, and several others, focusing on novel treatment mechanisms such as arginase inhibitors and mechanism-specific interventions [6][7] - The report emphasizes the importance of strategic collaborations and ongoing clinical trials, showcasing a proactive approach to developing effective therapies for malignant mesothelioma [6][7] - The industry is committed to improving patient outcomes through innovation, with a rich pipeline of therapies that may change the treatment paradigm for this challenging disease [7][8]

Core Viewpoint - Incyte's recent earnings report showed mixed results, with adjusted earnings missing estimates while total revenues grew year over year, driven by its lead drug Jakafi and the launch of Opzelura cream. The stock has seen a positive trend, outperforming the S&P 500, but analysts are cautious about future performance leading up to the next earnings release [1][2][3]. Financial Performance - Incyte reported Q1 2024 adjusted earnings of 64 cents per share, missing the Zacks Consensus Estimate of 88 cents, but up from 37 cents per share in the same quarter last year [2]. - Total revenues for the quarter were $881 million, reflecting a 9% year-over-year growth, but falling short of the Zacks Consensus Estimate of $935.8 million [3]. - Jakafi revenues were $571.8 million, down 1% year over year, missing the consensus estimate of $634 million [4]. - Opzelura cream generated $85.7 million in sales, a 52% increase year over year, but also missed the consensus estimate of $100 million [5][6]. - Zynyz, a newly approved drug, generated $0.46 million in sales, while Iclusig sales were $30.3 million, up 10% year over year, beating estimates [7]. - Minjuvi's revenues surged 264% to $23.8 million, exceeding the consensus estimate of $21.9 million [8]. Expenses and Cash Position - Adjusted research and development expenses totaled $388.4 million, up 3% year over year, while adjusted selling, general and administrative expenses were $277.3 million, down 6% [11]. - As of March 31, 2024, Incyte's cash and cash equivalents stood at $3.9 billion, an increase from $3.7 billion at the end of 2023 [12]. Guidance and Pipeline Updates - Incyte reiterated its 2024 guidance, expecting Jakafi revenues between $2.69 billion and $2.75 billion, with adjusted R&D expenses projected at $1.58 billion to $1.61 billion [13]. - The FDA accepted the biologics license application for axatilimab for Priority Review, with a decision expected on August 28, 2024 [14][15]. Market Sentiment and Estimates - Recent estimates for Incyte have trended downward, with a consensus estimate shift of -5.85% [16]. - The company currently holds a Zacks Rank 3 (Hold), indicating expectations for an in-line return in the coming months [18].

Shares of Incyte (INCY) moved up 7.2% in the past week compared with the industry's rise of 2.1%. The upside followed after INCY announced a share repurchase authorization of $2.0 billion. Investors cheered the news as the move will increase returns for the shareholders who were earlier disappointed with the first-quarter results. Incyte commenced a modified 'Dutch Auction' tender offer to repurchase shares of its common stock for an aggregate purchase price of up to $1.672 billion. Incyte is offering to pu ...

UKRAINE - 2021/05/24: In this photo illustration, Incyte Corp logo of a pharmaceutical company is ... [+] seen displayed on a smartphone and pc screen. (Photo Illustration by Pavlo Gonchar/SOPA Images/LightRocket via Getty Images) SOPA Images/LightRocket via Getty Images The stock price of Incyte Incyte , a biopharmaceutical company, trades at $58 per share, about 43% below its peak level of $100 seen in January 2021. INCY stock was trading at around $76 in early June 2022, just before the Fed started incre ...

Key Takeaways Major U.S. equities indexes were mixed and little changed Monday to kick off a new trading week that will provide investors with a few key economic data points. The latest monthly survey by the Federal Reserve Bank of New York released Monday showed that consumer expectations for inflation over the coming year rose in April. Inflation will likely remain in focus, with the Consumer Price Index (CPI) report set to be released on Wednesday, potentially influencing the Federal Reserve's upcoming p ...