Lexicon Pharmaceuticals Inc. (NASDAQ:LXRX) is one of the best fast growing penny stocks to buy according to analysts. On January 14, Citi analyst Yigal Nochomovitz increased the price target for Lexicon to $2.10 from $1.90 while maintaining a Buy rating. This upward revision resulted from an updated financial model that accounted for upcoming milestones under the LX9851 partnership with Novo Nordisk. In Q3 2025, Lexicon Pharmaceuticals Inc. (NASDAQ:LXRX) reported revenue of $14.2 million, which was drive ...

THE WOODLANDS, Texas, Jan. 30, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) (“Lexicon”) today announced the pricing of its previously announced underwritten public offering of 32,000,000 shares of its common stock, par value $0.001. The shares of common stock being offered pursuant to the public offering are being offered at a public offering price of $1.30 per share. All of the shares are being offered by Lexicon. The gross proceeds from the public offering are expected to be $41.6 ...

On January 14, Lale Akoner, global market analyst at eToro, appeared on CNBC to state that 2026 is driven by rotation into small caps and advised diversification. Recent data from BofA showed that customers had been selling equities over the six weeks leading up to that point, alongside observed outflows from ETFs that had previously seen consistent inflows. Akoner interpreted this not as a broad move away from risk assets, but rather as a significant rotation within the risk asset class. The shift is drive ...

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 29, 2026 Lexicon Pharmaceuticals, Inc. Registrant's telephone number, including area code Securities registered pursuant to Section 12(b) of the Act: | | Trading | Name of each exchange | | --- | --- | --- | | Title of each class | Symbol(s) | on which registered | | Common stock, par v ...

THE WOODLANDS, Texas, Jan. 29, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) (“Lexicon”) today announced that it has commenced an underwritten public offering to offer and sell, subject to market and other conditions, shares of its common stock, par value $0.001. In addition, Lexicon intends to grant the underwriters a 30-day option to purchase additional shares of common stock. There can be no assurance as to whether or when the proposed offering may be completed, or as to the actua ...

THE WOODLANDS, Texas, Jan. 23, 2026 (GLOBE NEWSWIRE) -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX) today announced the Company will ring the Nasdaq Stock Market Closing Bell on Tuesday, January 27, 2026. The event will commemorate Lexicon’s 30th anniversary as a biopharmaceutical company building a differentiated pipeline of oral small-molecule therapies for people living with serious cardiometabolic diseases and chronic neuropathic pain. “In its early days, Lexicon was focused on pioneering a deeper unde ...

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Core Insights - Lexicon Pharmaceuticals has successfully completed the End-of-Phase 2 meeting with the FDA for pilavapadin, which is advancing into Phase 3 development for diabetic peripheral neuropathic pain (DPNP) [1][2] - The FDA raised no objections to the Phase 3 program, which will include two placebo-controlled studies comparing a 10 mg daily dose of pilavapadin to placebo [1][2] Company Overview - Lexicon Pharmaceuticals is a biopharmaceutical company focused on pioneering medicines that transform patients' lives, utilizing its Genome5000™ program to study nearly 5,000 genes and identify over 100 protein targets with therapeutic potential [4] - The company has a pipeline of drug candidates in various stages of development, targeting conditions such as neuropathic pain, hypertrophic cardiomyopathy (HCM), obesity, and metabolism [4] Product Information - Pilavapadin is a once-daily, orally delivered small molecule inhibitor of AAK1, designed to treat neuropathic pain without affecting opiate pathways [3] - Preclinical studies have shown that pilavapadin penetrates the central nervous system and reduces pain behavior in neuropathic pain models [3]

PresentationGood afternoon, everyone. Welcome to the 44th Annual JPMorgan Healthcare Conference. My name is Alex Morrison. I'm an associate on JPM's health care team. Today, it's my pleasure to introduce Lexicon Pharmaceuticals. We'll have CEO, Mike Exton, speak; as well as Craig, Chief Medical Officer; and Scott, Chief Financial Officer, on stage for Q&A.Michael ExtonCEO & Director Great. So thanks so much, Alex, and thanks to JPMorgan for the invitation to present the Lexicon story. So for those of you wh ...

Lexicon Pharmaceuticals FY Conference Summary Company Overview - **Company**: Lexicon Pharmaceuticals (NasdaqGS:LXRX) - **Event**: 44th Annual JPMorgan Healthcare Conference - **Date**: January 15, 2026 Key Points Industry and Company Background - Lexicon Pharmaceuticals was founded 30 years ago with a focus on gene research, creating knockout mouse lines for 5,000 genes, identifying 200 genes of interest [2][3] - The company has conducted over 80 clinical trials, resulting in the approval of two medicines in the U.S., including INPEFA for heart failure and a novel approach for neuropathic pain [3][4] Product Pipeline and Therapeutic Areas - **Cardiometabolic Disease**: - INPEFA has been commercialized in the U.S. and is in phase three trials for hypertrophic cardiomyopathy (HCM) [5][9] - Zynquista is under regulatory discussions for type 1 diabetes [5][9] - LX9851 is a first-in-class non-incretin mechanism for obesity, currently licensed to Novo Nordisk [5][19] - **Pain Management**: - Pivapladin is a first-in-class AAK1 inhibitor for neuropathic pain, entering phase three trials in 2026 [6][18] - There is a significant unmet need in neuropathic pain, with approximately 9 million patients in the U.S. suffering from diabetic peripheral neuropathic pain (DPNP) [16][31] Clinical Trials and Regulatory Pathways - The SONATA trial for HCM is progressing well, with enrollment expected to conclude in the first half of 2026 [10][20] - The FDA has agreed on the parameters for resubmission of Zynquista, focusing on prospective data to assess the risk of diabetic ketoacidosis [27][28] - Pivapladin has shown significant placebo-adjusted improvements in pain scores, supporting its advancement into phase three trials [18][32] Market Opportunities - The cardiometabolic market is of high interest, particularly for HCM, which affects about 1 million people in the U.S. [11][25] - The DPNP market is characterized by a lack of effective treatments, creating a strong demand for new non-opioid options like Pivapladin [16][32] - The obesity treatment market is shifting towards oral medications, with a focus on improving tolerability and long-term adherence [33] Financial Position and Future Goals - Lexicon ended the previous year with approximately $125 million in cash, supporting operations into 2027 [20] - Goals for 2026 include advancing the late-stage pipeline, supporting partnerships with Novo Nordisk and Viatris, and maintaining financial discipline [20][36] Additional Insights - The company is focused on operational excellence and has implemented a virtual sales force for INPEFA to ensure continuous availability [8] - Legislative support for non-opioid pain treatments is growing, which may facilitate market access for Pivapladin [17][32] Conclusion Lexicon Pharmaceuticals is strategically positioned in the cardiometabolic and pain management sectors, with a robust pipeline and significant market opportunities. The company is focused on advancing its clinical trials and regulatory submissions while maintaining a strong financial position to support long-term growth.