Core Insights - PRF Technologies has undergone a significant transformation in 2025, repositioning itself as a diversified innovation platform in healthcare and renewable energy analytics [3] - The company made a majority investment in LayerBio, enhancing its healthcare pipeline with the OcuRing™-K, aimed at improving cataract surgery outcomes [4][5] - DeepSolar, acquired in March 2025, has transitioned from an acquisition to a commercial entity, focusing on AI-driven solar analytics [9][10] Healthcare Business Update - PRF's healthcare strategy evolved with the acquisition of LayerBio, expanding its focus to sustained-release ocular drug delivery [4] - OcuRing™-K is designed to deliver ketorolac during cataract surgery, potentially reducing the need for post-surgical eye drops [5][6] - The company is progressing towards a Phase II study for OcuRing™-K, with favorable safety data from preclinical and Phase I evaluations [5][6] DeepSolar Business Update - DeepSolar has launched a strategic pilot with Econergy at a 92 MW photovoltaic plant in Romania, leading to its first commercial customer agreement [10] - The company has developed a Smart Energy Management app and entered into a SaaS agreement for a 71 MW solar project in Romania [10][11] - DeepSolar's advancements reflect its growth in commercial deployment and analytics-driven solutions for solar asset management [12] Financial Results - Research and development expenses decreased to approximately $1.1 million in 2025 from $11.7 million in 2024, primarily due to reduced clinical trial costs [13] - General and administrative expenses remained stable at approximately $3.0 million for both years, with some offsetting factors [14] - The net loss for 2025 was approximately $4.8 million, a significant reduction from a net loss of approximately $14.6 million in 2024 [15]

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 20-F (Mark One) ☐ REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from ______ to ______ OR ☐ SHELL COMPANY REPORT PURSUANT TO SECTION 13 ...

Core Insights - PRF Technologies Ltd. has entered a commercial collaboration agreement with Blade Ranger Ltd. to enhance the expansion of its DeepSolar platform in utility-scale solar portfolios [1][2][7] - The agreement aims to facilitate multiple large-scale commercial engagements, each with a minimum capacity of 150 megawatts (MW), indicating significant potential for enterprise-level deployments [2] Company Overview - PRF Technologies focuses on AI-driven energy optimization technologies through its DeepSolar platform, which aims to improve solar asset performance and operational efficiency [5][11] - DeepSolar's platform utilizes AI-driven analytics to enhance energy production forecasting, reduce imbalance risk, and support participation in competitive electricity markets [5][6] - The company is also involved in pharmaceutical programs aimed at providing prolonged post-surgical pain relief, showcasing a dual business model in healthcare and sustainable energy [11] Industry Context - The global solar market is experiencing substantial growth, with hundreds of billions of dollars invested annually in new capacity, creating a demand for improved efficiency and profitability among utility-scale operators [6] - Utility-scale solar operators are increasingly adopting digital asset-management and AI-based optimization platforms to enhance margins and maximize asset value [6] - The partnership with Blade Ranger is expected to position DeepSolar favorably in the competitive landscape, as operators seek performance optimization and revenue predictability [4][7]

Core Insights - PRF Technologies Ltd. announced a solar analytics services agreement with EDF Group's subsidiary, marking a significant milestone for its DeepSolar business unit and a new revenue opportunity following the launch of Smart TDD [1][4] Group 1: Agreement Details - DeepSolar has initiated a technical due diligence engagement, analyzing historical and operational data of a utility-scale solar power plant in Israel [2][3] - The engagement utilizes DeepSolar's Smart TDD analytics to provide an independent technical review of the solar asset [2][3] Group 2: Service Features - Smart TDD is designed as a repeatable, analytics-driven due diligence solution applicable throughout a solar asset's lifecycle, supporting various use cases such as commissioning, warranty expiry, underperformance diagnosis, and asset acquisition [7][3] - The service generates structured outputs from plant data, facilitating informed decision-making for both technical teams and senior management [3][4] Group 3: Company Overview - PRF Technologies focuses on reformulating established therapeutics and developing AI-driven energy optimization technologies through its DeepSolar platform, reflecting a strategic commitment to healthcare and sustainable energy [6] - DeepSolar's AI algorithms convert complex operational data into actionable insights, enhancing asset performance and profitability [5][6]

Core Insights - PRF Technologies Ltd. has entered into a solar analytics services agreement with EDF Group's subsidiary for a utility-scale solar power plant in Israel, marking a significant milestone in DeepSolar's strategy and a new revenue opportunity following the launch of Smart TDD [1][2] Group 1: Agreement and Engagement - The agreement involves a technical due diligence (TDD) engagement, focusing on the analysis of historical and operational data of the solar plant [2] - DeepSolar's Smart TDD service will be utilized to conduct a structured, independent technical review of the solar asset [2][3] Group 2: Service Features and Applications - Smart TDD applies analytics to operational data to produce structured outputs for both technical teams and senior management, aiding in informed decision-making [4] - The service supports various use cases throughout a solar asset's lifecycle, including commissioning, warranty expiry assessments, underperformance diagnostics, and asset acquisition evaluations [8] Group 3: Company Overview and Technology - DeepSolar specializes in advanced digital asset management technologies for utility-scale solar plants, utilizing AI-driven algorithms to convert complex operational data into actionable insights [6] - The company is part of the NVIDIA Connect program, emphasizing its commitment to innovation in AI-powered renewable energy solutions [6]

Core Viewpoint - PRF Technologies has signed a SaaS agreement with Shikun & Binui Energy for the deployment of its DeepSolar platform at the 71 MW Satu Mare photovoltaic site in Romania, marking a significant step in the commercial rollout of its solar analytics solutions [1][2][5]. Group 1: Agreement Details - The Satu Mare project is a utility-scale solar plant that will utilize DeepSolar for continuous analytics and performance monitoring, enhancing operational visibility and supporting proactive asset management [2][3]. - This agreement signifies a commercial SaaS deployment, moving beyond pilot programs to support ongoing plant operations [2]. Group 2: Company Background - Shikun & Binui Energy is the renewable-energy subsidiary of Shikun & Binui Ltd., a leading infrastructure and construction group in Israel, with extensive experience in various sectors including energy and real estate [3]. - The deployment at Satu Mare reflects Shikun & Binui Energy's expansion in European renewable-energy markets, particularly in Romania [3]. Group 3: DeepSolar Platform - DeepSolar employs advanced analytics and machine-learning techniques to analyze operational data from solar plants, identifying performance trends and operational anomalies [4]. - The platform aims to support informed decision-making under varying market and grid conditions, enhancing asset performance and maximizing long-term value [5][7]. Group 4: Strategic Initiatives - PRF Technologies is expanding DeepSolar's capabilities, including the launch of Smart TDD for technical due diligence and the development of DeepSolar Predict for forecasting energy production [6]. - The company has filed a patent application related to plant-level micro-climate modeling, strengthening its intellectual property in solar analytics [6]. Group 5: Market Positioning - PRF Technologies aims to scale DeepSolar as a recurring SaaS platform for renewable-energy owners and financial stakeholders across European and international solar markets [7].

Core Insights - PRF Technologies has signed a SaaS agreement with Shikun & Binui Energy for the deployment of its DeepSolar platform at a 71 MW solar project in Romania, marking a significant step in the commercial rollout of its services in the European renewable energy market [1][2][5] Company Overview - Shikun & Binui Energy is a subsidiary of Shikun & Binui Ltd., a leading Israeli infrastructure and construction group with extensive experience in various sectors including energy and real estate [3] - PRF Technologies focuses on AI-driven energy optimization technologies and has a dual business model that includes both pharmaceutical programs and renewable energy solutions [10] Product and Technology - DeepSolar utilizes advanced analytics and machine learning to analyze operational data from solar plants, aiming to enhance performance monitoring and decision-making [4][8] - The platform is designed to identify performance trends, detect anomalies, and support asset management throughout the operational life of solar projects [2][4] Market Strategy - The agreement with Shikun & Binui Energy reflects PRF Technologies' strategy to scale DeepSolar as a recurring SaaS platform for renewable energy operators and financial stakeholders in Europe and beyond [7] - Recent initiatives include the launch of Smart TDD for technical due diligence and the development of DeepSolar Predict for forecasting energy production [6]

Core Insights - PRF Technologies Ltd. has filed a patent application for proprietary methods aimed at improving solar energy production forecasts through micro-climate modeling [2][3] - The patent is part of the company's strategy to enhance its intellectual property portfolio and expand in the renewable energy optimization market [7] Group 1: Patent and Technology - The patent application is designed to protect the core intellectual property of DeepSolar Predict, a solar forecasting software platform [3] - The technology addresses limitations in conventional solar forecasting by modeling localized weather conditions that affect individual solar plants [4] - The patented approach allows for more accurate short-term and intraday production forecasts, adapting to real-time environmental changes [4] Group 2: Commercial Implications - Improved forecasting accuracy can lead to better positioning in electricity markets, reduced financial penalties from forecast errors, and enhanced revenue during favorable pricing conditions [5] - The technology aims to support operational decision-making for solar asset owners and operators, ultimately improving financial performance [6] Group 3: Company Overview - PRF Technologies focuses on AI-driven energy optimization technologies and has a dual business model that includes pharmaceutical programs [9] - The company is committed to applying precision technology across sectors such as healthcare and sustainable energy [10] - DeepSolar's AI-driven algorithms are designed to maximize asset performance and profitability for utility-scale solar plants [8]

Core Viewpoint - PainReform Ltd. has changed its name to PRF Technologies Ltd. to better reflect its expanding portfolio, which now includes specialty pharmaceuticals and AI-driven renewable energy analytics [1][2]. Company Developments - The company is advancing its non-opioid postoperative pain therapy, PRF-110, and developing new products like OcuRing-K, a dropless ocular therapy for cataract surgery [3]. - PRF Technologies has established a presence in the renewable energy sector with DeepSolar, an AI-driven analytics platform for solar assets, which is moving into early commercial deployment [6]. Clinical and Preclinical Studies - In a phase 1 study, no treatment-emergent adverse events related to the study drug were observed, and no serious adverse events were reported [4]. - Preclinical rabbit studies showed favorable local tolerability for OcuRing-K, with no evidence of ocular tissue abnormalities [5]. Stock Performance - PRFX stock is currently trading 21.12% above its 20-day simple moving average (SMA) and 12.9% above its 100-day SMA, indicating short-term strength [7]. - Over the past 12 months, shares have decreased by 60.93% and are closer to their 52-week lows than highs [7]. - The stock is up 47.72% at $1.22 at the time of publication [12]. Technical Indicators - The RSI is at 47.81, indicating neutral territory, while the MACD is above its signal line, suggesting bullish momentum [7][8]. - Benzinga Edge scorecard indicates a "High-Flyer" setup with a momentum score of 83, but a low value score of 4 warns that the stock is priced for perfection [9][11].

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