Summary of SI-BONE (SIBN) FY Conference Call - June 10, 2025 Company Overview - **Company**: SI-BONE (SIBN) - **Industry**: Medical Devices, specifically focused on surgical solutions for the sacroiliac (SI) joint and pelvic fixation Key Points and Arguments Business Performance - The company is experiencing significant growth, with Q1 revenue growth of **25% worldwide** and **27% in the U.S.** [7][8] - Over **1,400 physicians** performed at least one case in Q1, marking a **300 increase year-over-year** [7] - The company achieved **adjusted EBITDA profitability** in Q1, which was not anticipated due to seasonal sales dips [8] - Revenue for the year is estimated to be **less than $200 million** [8] Market Dynamics - The company operates in a niche market, focusing on unmet clinical needs rather than competing directly with traditional spine companies [12][14] - The Total Addressable Market (TAM) for SI joint fusion is estimated at **280,000 cases per year**, with current market penetration at **less than 10%** [14][15] - The company has launched innovative products, including the **Granite** and **TNT** devices, which have received FDA breakthrough device designation [16][18] Product Development and Strategy - SI-BONE has transitioned from a one-product company to a multi-product company, focusing on the sacropelvic space [34] - The company aims to launch **two products per year**, with a focus on addressing unmet clinical needs [33] - The Granite product is expected to become the **standard of care** in deformity procedures [26] Financial Metrics - The company reported a **gross margin of 79.7%** in Q1, which is an increase of **80 basis points** from the previous year [51] - Guidance for gross margins in the mid-term is projected to be in the **76% to 77% range** due to new product launches and scaling [56] - Operating expenses (OpEx) are expected to grow by **10%** this year, with R&D seeing a lift due to new product launches [58] Sales and Marketing Strategy - The company is expanding its sales force to **100 territories** over the next 18 months [65] - A hybrid sales model is being utilized, combining direct sales with educational support for surgeons [43][46] - The company has implemented an **academic training program** to educate new surgeons on SI joint dysfunction, leading to higher adoption rates [40][41] Reimbursement and Pricing - The company has successfully secured **new technology add-on payments** for its products, enhancing initial adoption [48][49] - The Granite technology will have a transitional pass-through code effective January 2025, covering the full cost of the technology [48] Future Outlook - The company is optimistic about maintaining a **positive adjusted EBITDA** and free cash flow by 2026, driven by high gross margins and operational leverage [64][70] - There is a strong focus on clinical evidence to support new product launches and market expansion [66] Investor Sentiment - There is increasing interest from investors due to the company's consistent growth profile of over **20%** in recent years and demonstrated profitability [69][70] Additional Important Information - The company emphasizes its differentiation from traditional spine companies by focusing on specific clinical needs and innovative product development [12][14] - The management team is committed to educating investors about the company's unique position in the market [71]

Company Overview - SI-BONE, Inc. is a medical device company focused on addressing sacropelvic disorders and is recognized as a global leader in developing innovative surgical technologies [3] - The company pioneered minimally invasive SI joint surgery in 2009 with the introduction of the iFuse Implant System, supporting over 4,500 physicians and facilitating more than 120,000 procedures [3] - SI-BONE has established a strong clinical foundation with over 160 peer-reviewed publications, including two randomized controlled trials, validating the effectiveness of its technologies [3] Upcoming Event - SI-BONE will participate in the 2025 Truist Securities MedTech Conference in Boston, MA, with a fireside chat scheduled for June 17, 2025, at 10:00 a.m. Pacific Time [1] - Investors can register for the conference call and access a live audio webcast on the company's website, which will be archived for at least 90 days post-event [2]

Company Participation - SI-BONE, Inc. will participate in the 2025 Goldman Sachs 46 Global Healthcare Conference in Miami Beach, FL, hosting a fireside chat on June 10, 2025, at 8:20 a.m. Pacific Time [1] Company Overview - SI-BONE is a global leader in developing technologies for surgical treatment of sacropelvic disorders, having pioneered minimally invasive SI joint surgery in 2009 with the iFuse Implant System [3] - The company has supported over 4,500 physicians in performing more than 120,000 procedures, backed by over 160 peer-reviewed publications, including two randomized controlled trials [3] - SI-BONE has expanded its offerings to adjacent markets, including adult deformity, spinopelvic and sacropelvic fixation, and pelvic trauma [3]

Core Viewpoint - Si-Bone (SIBN) shares have increased by 27.6% in the past four weeks, closing at $18.38, with a mean price target of $24.67 indicating a potential upside of 34.2% [1] Price Targets and Analyst Estimates - The mean estimate consists of nine short-term price targets with a standard deviation of $3.57, where the lowest estimate is $19 (3.4% increase) and the highest is $32 (74.1% increase) [2] - A low standard deviation suggests a high degree of agreement among analysts regarding the stock's price movement [9] Earnings Estimates and Market Sentiment - Analysts are optimistic about SIBN's earnings prospects, as indicated by a positive trend in earnings estimate revisions, with five estimates moving higher and no negative revisions in the last 30 days, resulting in a 7.7% increase in the Zacks Consensus Estimate [11][12] - SIBN holds a Zacks Rank 2 (Buy), placing it in the top 20% of over 4,000 ranked stocks based on earnings estimates [13]

Group 1: Momentum Investing Overview - Momentum investing involves following a stock's recent trend, with the aim of buying high and selling higher, capitalizing on established price movements [1] - The Zacks Momentum Style Score helps investors identify which metrics to focus on for momentum, addressing the challenges in defining momentum [2] Group 2: Si-Bone (SIBN) Performance - Si-Bone currently holds a Momentum Style Score of B and a Zacks Rank of 2 (Buy), indicating strong potential for outperformance [3][4] - Over the past week, SIBN shares have increased by 32.17%, while the Zacks Medical - Instruments industry remained flat [6] - In a longer timeframe, SIBN shares have risen 14.58% over the past quarter and 25.2% over the past year, outperforming the S&P 500 which moved -3.09% and 13.39% respectively [7] Group 3: Trading Volume and Earnings Outlook - SIBN's average 20-day trading volume is 478,841 shares, which is a useful indicator of market interest and price movement [8] - In the past two months, 5 earnings estimates for SIBN have increased, raising the consensus estimate from -$0.67 to -$0.62 [10] - For the next fiscal year, 3 estimates have moved upwards while 1 has been revised downwards, indicating a positive trend in earnings outlook [10] Group 4: Conclusion - Considering the performance metrics and earnings outlook, SIBN is positioned as a promising momentum stock with a Momentum Score of B [12]

Summary of SI-BONE (SIBN) Conference Call - May 13, 2025 Company Overview - **Company**: SI-BONE (SIBN) - **Industry**: Medical Devices, specifically focused on spinal and orthopedic solutions Key Financial Highlights - **Q1 Revenue Growth**: 25% overall, with 27% growth in the US [3][6] - **Volume Growth**: 27% increase in volume, broad-based across all modalities [3][5] - **Active Physicians**: Added 300 active physicians in Q1, reaching a record of over 1,400 [4][5] - **Gross Margin**: Close to 80%, with an 80 basis point improvement [5][22] - **Adjusted EBITDA**: Positive for the second consecutive quarter [6][30] - **Cash Burn**: Declined by approximately 32% [6] Market and Product Insights - **Total Addressable Market (TAM)**: - SI joint dysfunction: $2.5 billion - Pelvic fixation: $1 billion - Trauma market: $300 million [9][10] - **Core Business**: SI joint dysfunction remains the largest segment, with new product launches contributing to growth [10][11] - **New Product Launches**: - Torque (2021) and Intra (2024) have been significant growth drivers [10][11] - Upcoming product targeting SI joint dysfunction expected in Q1 2026 [11][54] Guidance and Future Outlook - **Guidance Approach**: Conservative, with a thoughtful approach to setting expectations for the remainder of 2025 [14][16] - **Long-term Growth Drivers**: - Technology leadership and physician engagement for new products [15][16] - Reimbursement tailwinds from NTAP and TPT [15][16] - **Q2 and Q3 Expectations**: Anticipated variability due to seasonal factors and macroeconomic conditions [20][21] Operational Efficiency - **Operating Leverage**: Revenue growth has consistently outpaced operating expense growth, with a target of 1.75x revenue to OpEx growth [30][32] - **R&D Investments**: Continued focus on R&D for new products, with elevated spending expected [31][34] Physician Engagement Metrics - **Active Physician Growth**: Four years of double-digit growth, doubling the active physician base over the last two years [39][40] - **Procedure Volume**: 30% increase in same-store sales for procedures performed by existing physicians [42] Interventional Strategy - **Interventional Market Engagement**: Focus on interventional spine physicians, with successful product launches leading to increased adoption [46][48] - **New Product for Interventionalists**: Expected to simplify workflows and attract new interventionalists [49][51] Pipeline Products - **Upcoming Products**: - SI joint dysfunction product expected in Q1 2026 [54][56] - Third BDD product in development, targeting pressing issues in the spine industry [54][55] Conclusion - **Overall Performance**: Strong Q1 results provide a solid foundation for continued growth, with a focus on expanding physician engagement and product offerings in the medical device market [6][15]

Group 1 - Si-Bone (SIBN) shares have increased by 25.5% over the past four weeks, closing at $17.47, with a mean price target of $24.67 indicating a potential upside of 41.2% [1] - The mean estimate consists of nine short-term price targets with a standard deviation of $3.57, where the lowest estimate is $19 (an 8.8% increase) and the highest is $32 (an 83.2% increase) [2] - Analysts show strong agreement on SIBN's ability to report better earnings, with a positive trend in earnings estimate revisions correlating with potential stock price increases [4][11] Group 2 - The Zacks Consensus Estimate for SIBN has increased by 7% due to four upward revisions in earnings estimates over the last 30 days, with no negative revisions [12] - SIBN holds a Zacks Rank 2 (Buy), placing it in the top 20% of over 4,000 ranked stocks based on earnings estimate factors, indicating strong potential for upside [13] - While price targets can be misleading, the direction implied by them may serve as a useful guide for further research into SIBN's fundamentals [10][11]

Company Overview - SI-BONE, Inc. is a medical device company focused on addressing sacropelvic disorders and is recognized as a global leader in developing surgical technologies for these conditions [3] - The company pioneered minimally invasive SI joint surgery in 2009 and has supported over 4,500 physicians in performing more than 120,000 procedures [3] - SI-BONE has established a strong clinical evidence base, including two randomized controlled trials and over 160 peer-reviewed publications [3] Upcoming Event - SI-BONE will participate in the 2025 BofA Securities Healthcare Conference in Las Vegas, with a fireside chat scheduled for May 13, 2025, at 8:40 a.m. Pacific Time [1] - Investors can listen to the conference call by registering online, and a live audio webcast will be available on the company's website [2]

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark one) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from __________ to __________ Commission File Number: 001-38701 SI-BONE, INC. (Exact Name of Registrant as Specified in its Charter) (State or Other Jurisdiction o ...

Financial Performance - SI-BONE achieved a worldwide revenue growth of 24.9% reaching $47.3 million in 1Q25[8] - U S revenue grew by 26.6% to $44.8 million in 1Q25[8] - The company reported a gross margin of 79.7%, an improvement of 80 basis points[8] - Adjusted EBITDA turned positive at $0.5 million, a 112% year-over-year improvement[8, 15] - The company expects to have $144.4 million in cash and equivalents[16] Physician Engagement and Procedure Volume - SI-BONE added a record 300 U S physicians in 1Q25[6] - There was a 27.1% growth in U S active physicians[8] - U S procedure volume increased by approximately 27% from 4,000 in 1Q24 to 5,100 in 1Q25[10] - The U S active physician base grew by approximately 27% from 1,100 in 1Q24 to 1,400 in 1Q25[12] Product and Market Opportunity - The company is developing a third breakthrough-designated device, iFuse TORQ TNT[6] - SI-BONE is pursuing a proposed New Technology Add-On Payment (NTAP) of $3,960 for iFuse TORQ TNT[6] - The total U S addressable market for SI-BONE's products is estimated to be over $3.5 billion, with less than 10% currently penetrated[21, 29] Future Outlook - The company updated its 2025 worldwide revenue guidance to $193.5 - $197.5 million, implying a growth of approximately 16%-18%[19, 20]