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Thiogenesis Reports Positive Interim Phase 2 Trial Results for MELAS and Announces Pipeline Advancements in Leigh Syndrome and Cystinosis
Newsfile· 2025-11-04 14:00
Core Insights - Thiogenesis Therapeutics reported positive interim results from its Phase 2 clinical trial of TTI-0102 for MELAS, achieving biological proof-of-concept, dose discovery, and biomarker improvement [1][2][5] MELAS Clinical Trial - The Phase 2 trial included nine patients, with six receiving TTI-0102 and three on placebo, focusing on biological proof-of-concept, dose discovery, and early efficacy [2] - Five active patients remain in the trial, with TTI-0102 well tolerated, although four patients under 50 kg left due to dose-dependent side effects, indicating a need for refined dosing protocols [3] - The interim analysis showed significant support for TTI-0102's mitochondrial antioxidant and restorative activity, with individual biomarker data remaining confidential until early 2026 [4] Future Plans and Pipeline Updates - The company anticipates final 6-month data from the MELAS cohort by January 2026 and plans to file an Investigational Medicinal Product Dossier (IMPD) to initiate a pivotal Phase 3 trial in Europe in 2026 [6][7] - For Leigh syndrome spectrum, the FDA accepted the IND application, with a Phase 2 trial expected to start in early 2026, incorporating dosing adjustments based on MELAS interim data [8] - The company plans to file an IND application for a Phase 3 trial in nephropathic cystinosis, comparing TTI-0102 to current cysteamine therapies, which have significant side effects [9][10] About TTI-0102 - TTI-0102 is a disulfide compound designed to overcome limitations of existing thiol-based drugs, offering potential for once-daily dosing and improved tolerability [15] - The compound targets mitochondrial dysfunction, with applications in MELAS and other pediatric diseases [16]
TETRA Technologies, Inc. 2025 Q3 - Results - Earnings Call Presentation (NYSE:TTI) 2025-10-29
Seeking Alpha· 2025-10-30 02:02
Group 1 - The article does not provide any relevant content regarding company or industry insights [1]
TETRA Technologies(TTI) - 2025 Q3 - Earnings Call Transcript
2025-10-29 15:30
Financial Data and Key Metrics Changes - The company achieved record revenue of $484 million and adjusted EBITDA of $93 million over the past 10 years, with Q3 revenue at $153 million and adjusted EBITDA at $25 million, reflecting an 8% year-over-year increase in revenue and a 7% rise in adjusted EBITDA [6][7][19] - Adjusted EBITDA margins for Q3 were 16%, with completion fluids and products revenues increasing 39% year-over-year [7][8] - The company ended Q3 with $67 million in cash and a net leverage ratio of 1.2 times, with working capital at $113 million, only a $4 million increase from year-end [17][18] Business Line Data and Key Metrics Changes - Completion fluids and products saw a significant revenue increase, with adjusted EBITDA margins reaching 34.5%, a 500 basis point improvement compared to the same period in 2024 [8][9] - Water and flowback services revenue declined 2% sequentially and 18% year-over-year, but adjusted EBITDA rose 18% sequentially due to better cost controls [9][10] - The industrial calcium chloride business continues to perform well, with record quarters and expansion into new applications [48][49] Market Data and Key Metrics Changes - The deepwater rig count is currently 40% lower than it was 10 years ago, yet the company has achieved significant market penetration [6][7] - The company is experiencing increased unconventional activity in Argentina and the Middle East, with 100% utilization of automated SandStorm units in Argentina [10][11] - The outlook for the completion fluids and products business remains strong, driven by deepwater completion activity and increased demand for battery electrolyte revenue [9][12] Company Strategy and Development Direction - The company unveiled its "One TETRA 2030" strategy, aiming to leverage its core fluids chemistry expertise into high-growth markets, including battery electrolytes and produced water desalination solutions [12][13] - The goal is to more than double revenue to over $1.2 billion and triple adjusted EBITDA to over $300 million by 2030 [13][16] - The company is focused on generating over $100 million in annual adjusted free cash flow by 2030, driving meaningful cash returns to shareholders [16] Management's Comments on Operating Environment and Future Outlook - Management expressed strong conviction in the long-term outlook despite macroeconomic and energy market uncertainties, highlighting the company's ability to differentiate in its markets [23][62] - The company anticipates continued offshore activity growth, particularly in the Gulf of America, Brazil, and North Sea, with confidence in executing TETRA Neptune projects in 2026 [31][55] - The company is optimistic about the desalination market, expecting to sign its first commercial contract in the coming quarters [15][44] Other Important Information - Elijio Serrano, the CFO, announced his retirement at the end of March 2026, with Matthew Sanderson set to replace him [4][5] - The company is relocating to a new corporate office, expecting to reduce lease expenses by approximately $2 million per year [18][19] Q&A Session Summary Question: Update on Oasis Commercial Engineering and next steps - The FEED study has been completed, and discussions with customers are ongoing to socialize the economics and financials [25][26] Question: Factors behind sequential decline in CFP sales - The decline was primarily due to seasonal industrial calcium chloride sales and the absence of Neptune jobs, partially offset by increased activity in Brazil [27][28] Question: Confidence in offshore market for 2026 and 2027 - Management expressed strong confidence in the deepwater market's growth, with a robust pipeline for TETRA Neptune projects [31][32] Question: Update on desalination projects and capital costs - The core technology will remain owned by TETRA, with various commercial models being considered, and capital costs are estimated at $1 million per 1,000 barrels of desalination [33][34] Question: Outlook for 2026 compared to 2025 - The company expects significant growth in Argentina and the Middle East, with a strong outlook for deepwater projects [36][38] Question: Opportunities in Saudi Arabia and Sandstorm - The company sees potential for growth in Saudi Arabia, similar to the success experienced in Argentina [58][59]
TETRA Technologies(TTI) - 2025 Q3 - Earnings Call Presentation
2025-10-29 14:30
Company Overview - TETRA's market capitalization is $105 billion as of October 24, 2025[14] - The company's net debt is $114 million as of September 30, 2025[14] - The enterprise value is $117 billion as of October 24, 2025[14] - Q3 2025 TTM revenue is $619 million, with an adjusted EBITDA margin of 187%[15,21] Financial Performance and Targets - 2024 revenue was $599 million, with adjusted EBITDA of $994 million[20] - 2025 revenue guidance is $620-630 million, with adjusted EBITDA of $107-112 million[20] - The company targets 2030 revenue of $125 billion, representing a 15% CAGR, and adjusted EBITDA of $325 million, with a 26% adjusted EBITDA margin[146] Business Segments and Growth - Completion Fluids & Products revenue is $362 million TTM, with an adjusted EBITDA margin of 331%[15,41] - Water & Flowback Services revenue is $257 million TTM, with an adjusted EBITDA margin of 121%[15] - The company is transitioning to three future segments: Energy Services, Specialty Chemicals & Minerals, and Water Treatment & Desalination[27] Critical Minerals and Bromine Project - TETRA has over 40000 acres of mineral-rich Smackover brine leases[115] - The Arkansas Bromine Project has a projected incremental revenue of $230 million and incremental EBITDA of $105 million at full production[124] - The Arkansas Bromine Project has a project capex of $270 million, an NPV10 of $710 million, and an IRR of 62%[124]
Tetra Technologies, Inc. (NYSE:TTI) Showcases Strong Q3 2025 Financial Performance
Financial Modeling Prep· 2025-10-29 10:02
Core Viewpoint - Tetra Technologies, Inc. reported solid financial results for Q3 2025, demonstrating growth in revenue and adjusted EBITDA despite challenges in the U.S. onshore oil and gas markets [2][3]. Financial Performance - Earnings per share (EPS) for Q3 2025 were $0.04, matching estimates and up from $0.03 in the same quarter last year [2][6]. - Revenue for the quarter reached $153.2 million, exceeding estimates of $144.4 million and representing an 8% increase from $141.7 million in the previous year [2][6]. - Adjusted EBITDA was $25 million, a 7% increase year-over-year, with a ten-year high of $93 million for the first nine months of 2025 [3][6]. Market Position and Valuation - Tetra has a price-to-earnings (P/E) ratio of approximately 9.00, indicating a relatively low valuation compared to its earnings [4]. - The price-to-sales ratio stands at about 1.71, and the enterprise value to sales ratio is around 1.95, reflecting the company's market valuation and cash flow efficiency [4]. Financial Stability - The company has a debt-to-equity ratio of 0.75, indicating moderate debt levels [5]. - A current ratio of 2.47 suggests a strong ability to cover short-term liabilities with short-term assets [5]. - Tetra reported net cash from operating activities of $16.4 million and a base business free cash flow of $5.4 million, underscoring its financial stability [5].
Tetra Technologies (TTI) Meets Q3 Earnings Estimates
ZACKS· 2025-10-28 23:16
Core Viewpoint - Tetra Technologies reported quarterly earnings of $0.04 per share, matching the Zacks Consensus Estimate, and showing an increase from $0.03 per share a year ago [1] - The company achieved revenues of $153.24 million for the quarter ended September 2025, exceeding the Zacks Consensus Estimate by 6.42% and up from $141.7 million year-over-year [2] Financial Performance - Tetra Technologies has surpassed consensus revenue estimates three times over the last four quarters [2] - The company has only exceeded consensus EPS estimates once in the last four quarters [1] Stock Performance - Tetra Technologies shares have increased approximately 113.4% since the beginning of the year, significantly outperforming the S&P 500's gain of 16.9% [3] Future Outlook - The company's earnings outlook will be crucial for determining future stock performance, with current consensus EPS estimates at $0.03 for the coming quarter and $0.18 for the current fiscal year [4][7] - The Zacks Rank for Tetra Technologies is currently 3 (Hold), indicating expected performance in line with the market in the near future [6] Industry Context - The Oil and Gas - Field Services industry, to which Tetra Technologies belongs, is currently ranked in the bottom 36% of over 250 Zacks industries, suggesting potential challenges ahead [8]
TETRA Technologies(TTI) - 2025 Q3 - Quarterly Report
2025-10-28 21:03
Financial Performance - Consolidated revenue for the first nine months of 2025 was $484.3 million, a 4.2% increase compared to $464.6 million in the same period of 2024[88][104] - Consolidated gross profit for the first nine months of 2025 was $127.5 million, up 17.3% from $108.7 million in the prior year[104][105] - Consolidated net income attributable to TETRA stockholders for the nine months ended September 30, 2025, was $19.5 million, a 250.8% increase from $5.6 million in the same period of 2024[104] - Operating income for the first nine months of 2025 was $52.9 million, reflecting a 26.3% increase compared to $41.9 million in the prior year[104] - Consolidated income from continuing operations before taxes increased by 52.8% to $32.6 million for the nine months ended September 30, 2025, compared to $21.4 million in the prior year[104] Division Performance - Completion Fluids & Products Division revenues increased due to strong performance in the deepwater Gulf of America, particularly from the three-well CS Neptune project[89] - Consolidated revenues for the Completion Fluids & Products Division increased by $50.3 million, or 20.7%, to $292.7 million for the nine months ended September 30, 2025, compared to $242.4 million in 2024[109] - Gross profit for the Completion Fluids & Products Division rose by $27.1 million, or 32.1%, to $111.6 million, driven by stronger volumes and higher-margin product sales[109] - Revenues for the Water & Flowback Services Division decreased by $30.7 million, or 13.8%, to $191.5 million, attributed to lower drilling activity in the U.S. and reduced service revenues[111] - Operating income for the Water & Flowback Services Division turned to a loss of $83, a decrease of $10.2 million, or 100.8%, compared to a profit of $10.1 million in the prior year[111] Cash Flow and Expenditures - Consolidated cash flows from operating activities increased to $68.6 million for the nine months ended September 30, 2025, compared to $30.9 million in 2024[115] - Total cash capital expenditures for the first nine months of 2025 were $53.2 million, with $37.2 million allocated to the Arkansas brine resource development[117] - The company reported liquidity of $208.1 million at the end of the third quarter, consisting of unrestricted cash and available credit[114] Future Projects and Expectations - The company expects the bromine processing plant in Arkansas to be operational by the end of 2027, with first production anticipated in 2028[91] - The TETRA Oasis Total Desalination Solution ("TDS") is being developed for re-use and mineral extraction applications, with engineering design for the first commercial plant already completed[92] Risks and Uncertainties - The Company anticipates future events and financial performance based on reasonable assumptions, but these forward-looking statements are subject to numerous risks and uncertainties[136] - The Company is exposed to currency exchange rate risks related to revenues, expenses, and operating receivables in foreign currencies, but had no foreign currency exchange contracts outstanding as of September 30, 2025[141] - The Company faces competition from existing and new competitors, which may impact its market position and financial performance[138] - The Company is subject to risks related to acquisitions and its growth strategy, including emerging growth initiatives[136] - The Company acknowledges the potential impact of global health concerns, geopolitical tensions, and regulatory changes on its operations and financial results[136] - The Company cautions investors regarding the economic viability of its mineral resources and the uncertainties related to their development[137] Financial Agreements - The Company has a Term Credit Agreement with a scheduled maturity on January 1, 2030, bearing an interest rate of 10.01% on a principal amount of $190,000,000[140] - As of September 30, 2025, the Company had no borrowings outstanding under its ABL Credit Agreement or Swedish Credit Facility[139] - The Company has not entered into any interest rate swap contracts or other derivatives to hedge against interest rate fluctuations[139] Taxation - The effective tax rate decreased to 40.2% from 46.7% in the prior year, primarily due to an out-of-period adjustment[108]
TETRA Technologies(TTI) - 2025 Q3 - Quarterly Results
2025-10-28 21:03
Financial Performance - Revenue for Q3 2025 was $153 million, an 8% increase year-over-year[6] - Adjusted EBITDA for Q3 2025 was $25.0 million, a 7% increase year-over-year, with adjusted EBITDA margins at 16.3%[6] - Completion Fluids & Products revenue increased 39% year-over-year, with adjusted EBITDA rising by $6.9 million[5] - Revenues for Q3 2025 were $153,239,000, a decrease of 11.9% from $173,872,000 in Q2 2025 and an increase of 8.1% from $141,700,000 in Q3 2024[36] - Gross profit for Q3 2025 was $36,370,000, down 24.6% from $48,244,000 in Q2 2025 but up 5.8% from $34,363,000 in Q3 2024[36] - Operating income for Q3 2025 was $11,130,000, a decline of 51.5% from $22,985,000 in Q2 2025 but consistent with $11,957,000 in Q3 2024[36] - Net income attributable to TETRA stockholders for Q3 2025 was $4,151,000, down 63.3% from $11,305,000 in Q2 2025 and a recovery from a loss of $2,998,000 in Q3 2024[36] - Adjusted net income for Q3 2025 was $5,437,000, compared to $12,618,000 in Q2 2025 and $3,343,000 in Q3 2024, reflecting a decrease of 57.0% quarter-over-quarter and an increase of 62.5% year-over-year[40] - Adjusted EBITDA for Q3 2025 was $25,038,000, representing 16.3% of total revenue, compared to $35,879,000 and 20.6% in Q2 2025, showing a decrease of 30.2%[41] Cash Flow and Liquidity - Total adjusted free cash flow for Q3 2025 was a use of cash of $0.6 million, while base business free cash flow was $5.4 million[29] - Liquidity at the end of Q3 2025 was $208 million, including $67 million in cash and cash equivalents[30] - Net cash provided by operating activities for Q3 2025 was $16,366,000, a decrease of 66.1% from $48,333,000 in Q2 2025 but an increase from $19,870,000 in Q3 2024[38] - Total adjusted free cash flow for Q3 2025 was $(628,000), compared to $26,492,000 in Q2 2025, indicating a significant decline[45] Assets and Liabilities - Total current assets increased to $313,880,000 as of September 30, 2025, compared to $269,628,000 at the end of 2024, reflecting a growth of 16.4%[37] - Cash and cash equivalents rose to $67,146,000 from $36,987,000 at the end of 2024, marking an increase of 81.8%[37] - Total assets reached $655,174,000 as of September 30, 2025, up from $605,195,000 at the end of 2024, indicating an increase of 8.3%[37] - The company reported a total long-term debt of $180,924,000 as of September 30, 2025, slightly up from $179,696,000 at the end of 2024[37] - Net debt as of September 30, 2025, was $113,778,000, down from $142,709,000 as of December 31, 2024, reflecting a reduction of 20.3%[47] - Total debt and commitments as of September 30, 2025, amounted to $196,615,000, with a net leverage ratio of 1.2[49] Future Guidance and Investments - Full year 2025 revenue guidance is between $620 million and $630 million, an increase from previous guidance[8] - The company aims to double revenue to over $1.2 billion and triple adjusted EBITDA to over $300 million by 2030[21] - The Arkansas bromine processing facility has received $28 million in investments, with Phase 1 expected to be operational by year-end 2027[7] - TETRA's new TDS water desalination technology is in the design phase for a 25,000 barrel per day facility, with commercial discussions ongoing[7] - Adjusted EBITDA for the projected year 2025 is estimated to be between $107,000,000 and $112,000,000, compared to the actual $99,403,000 for 2024[51] Operational Expenses - The company incurred transaction, restructuring, and other expenses of $1,188,000 in Q3 2025, compared to $1,242,000 in Q2 2025[41] - Interest expense for the twelve months ended September 30, 2025, was $18,598,000, with a projected interest expense for 2025 between $17,581,000 and $18,400,000[51] - The company expects to incur a non-cash charge of approximately $8 million related to the lease agreement for new corporate office space[51] - The company reported an unusual foreign currency loss of $9,516,000 for the twelve months ended September 30, 2025[49] - Equity-based compensation expense for the twelve months ended September 30, 2025, was $6,983,000, with a projected range for 2025 between $6,900,000 and $7,100,000[51] - The company anticipates a reduction in lease expenses of approximately $2 million per year in the new facility compared to the current office lease[51] Strategic Initiatives - TETRA is expanding into the low-carbon energy market, leveraging its chemistry expertise and global infrastructure to meet sustainable energy demands[34] - Management uses the net leverage ratio primarily to assess the company's ability to borrow, reduce debt, and fund investing and financing activities[49]
TETRA TECHNOLOGIES, INC. ANNOUNCES STRONG THIRD QUARTER 2025 RESULTS
Prnewswire· 2025-10-28 21:00
Core Insights - TETRA Technologies reported a strong financial performance in Q3 2025, achieving a ten-year high adjusted EBITDA of $93 million for the first nine months, with Q3 adjusted EBITDA at $25 million and a margin of 16.3% despite challenges in the U.S. onshore oil and gas markets [2][4][6] Financial Performance - Revenue for Q3 2025 was $153 million, an 8% increase year-over-year, while adjusted EBITDA rose by 7% to $25 million [6][5] - Net income before taxes was $8.1 million, remaining flat year-over-year, with earnings per share at $0.03 and adjusted earnings per share at $0.04 [6][5] - The company ended Q3 with $67 million in cash and a net leverage ratio of 1.2 times trailing twelve-month adjusted EBITDA [3][24] Segment Performance - Completion Fluids & Products revenue increased by 39% year-over-year, with adjusted EBITDA margins reaching 30.5% [7][3] - Water & Flowback Services revenue decreased by 2% sequentially but saw an 18% decline year-over-year, with adjusted EBITDA margins improving to 11.9% due to cost control measures [9][3] Growth Initiatives - TETRA is advancing its Arkansas bromine processing facility, with an investment of $28 million and plans for full operational capacity by the end of 2027 [3][12] - The company is also focused on battery electrolyte production, anticipating significant revenue growth as Eos Energy ramps up deliveries from its automated production line [20][8] Full Year Guidance - For the full year 2025, TETRA expects GAAP net income before taxes to be between $19 million and $27 million, with adjusted EBITDA projected between $107 million and $112 million [4][6]
Top Players in Singapore Oilfield Services Market and How to Benchmark Their Strategies (2026)
Medium· 2025-10-16 04:33
Market Overview - The Singapore Oilfield Services Market was valued at USD 1.55 Billion in 2024 and is projected to reach USD 2.52 Billion by 2032, with a CAGR of 6.2% from 2025 to 2032 [1][21]. Technological Advancements - Artificial intelligence is enhancing operational efficiency, safety standards, and resource utilization in the oilfield services industry, enabling predictive maintenance and advanced seismic interpretation [2][4]. - The integration of smart sensors and robotics is improving well integrity management and production optimization, leading to safer operations and reduced environmental impact [3][4]. Market Dynamics - The market is influenced by a global push towards sustainability and technological advancement, with new regulations emphasizing environmental performance and digital transformation [6][10]. - Singapore's strategic positioning as a regional energy hub, along with its robust regulatory environment, supports the growth of high-value services and technological innovation [7][8]. Key Players - Major companies in the oilfield services market include Schlumberger Limited, Halliburton Company, and Baker Hughes Company, focusing on sustainable and low-carbon solutions [11][16]. Growth Segments - The fastest-growing segments are expected to be analytical services and subsea services, driven by the need for data-driven insights and complex deepwater developments [24][28]. Future Outlook - The market outlook remains positive, with sustained energy demand and ongoing technological advancements expected to drive growth, particularly in specialized services related to digital transformation and decarbonization efforts [21][29].