Waystar to acquire Iodine Software ANNOUNCEMENT July 23, 2025 © 2025 Waystar. All rights reserved. F O R W A R D - L O O K I N G S T A T E M E N T S This presentation contains forward-looking statements, within the meaning of the Private Securities Litigation Reform Act of 1995, that reflect our current views with respect to, among other things, statements regarding Waystar's expectations relating to future operating results and financial position, including full year 2025, and future periods; anticipated f ...

Exhibit 2.1 Strictly Confidential EXECUTION VERSION AGREEMENT AND PLAN OF MERGER BY AND AMONG WAYSTAR HOLDING CORP., MORTON MERGER SUB 1, INC., ISOTOPE HOLDING, LLC, ISOTOPE SOFTWARE PARENT, LLC, IODINE SOFTWARE HOLDINGS, INC. AND SHAREHOLDER REPRESENTATIVE SERVICES LLC, as Equityholder Representative Dated as of July 23, 2025 TABLE OF CONTENTS | | | Page | | --- | --- | --- | | | Article I DEFINITIONS | 2 | | 1.1 | Certain Definitions | 2 | | 1.2 | Terms Defined Elsewhere in this Agreement | 18 | | 1.3 | O ...

Core Insights - Waystar has announced a definitive agreement to acquire Iodine Software for a total enterprise value of $1.25 billion, aiming to enhance its healthcare payment solutions through advanced AI capabilities [1][2][4] - The acquisition is expected to be immediately accretive to Waystar's gross margin, adjusted EBITDA margin, revenue growth, and non-GAAP net income per diluted share by 2027 [2] - The combined entity is projected to expand Waystar's total addressable market by more than 15% and unlock new automation opportunities across the revenue cycle [7][14] Company Overview - Waystar is a provider of healthcare payment software, serving approximately 30,000 clients and over 1 million distinct providers, processing more than 6 billion healthcare payment transactions annually [13] - Iodine Software specializes in AI-powered clinical intelligence, helping to eliminate revenue leakage and lower administrative burdens for healthcare providers [15] Strategic and Financial Benefits - The acquisition is expected to streamline cumbersome tasks for providers and enhance the impact of Waystar's AI capabilities in clinical documentation integrity and revenue leakage identification [6][14] - Waystar anticipates realizing over $15 million in run-rate cost synergies within the first 18-24 months post-acquisition [14] Transaction Details - The transaction will be funded with a 50/50 mix of cash and stock, with current Waystar shareholders owning approximately 92% of the combined company post-transaction [8][9] - The deal is expected to close by year-end 2025, subject to customary closing conditions and regulatory approvals [9] Market Context - The healthcare industry faces approximately $440 billion in annual administrative costs, with up to 60 million claims denied each year due to administrative errors, highlighting the need for improved clinical documentation and coding [3][4] - The integration of Iodine's clinical intelligence software is expected to enhance Waystar's existing capabilities and deepen relationships with leading health systems, potentially serving 17 of the 20 U.S. News Best Hospitals [14]

Core Viewpoint - The market anticipates Waystar Holding (WAY) to report a year-over-year increase in earnings driven by higher revenues in its upcoming earnings report for the quarter ended June 2025, with actual results being crucial for stock price movement [1][2]. Earnings Expectations - Waystar is expected to post quarterly earnings of $0.33 per share, reflecting a significant year-over-year increase of +725% [3]. - Revenues are projected to reach $254.09 million, marking an 8.3% increase from the same quarter last year [3]. Estimate Revisions - The consensus EPS estimate has remained unchanged over the last 30 days, indicating stability in analyst expectations [4]. - The Most Accurate Estimate for Waystar is higher than the Zacks Consensus Estimate, resulting in a positive Earnings ESP of +1.54%, suggesting a bullish outlook from analysts [11]. Earnings Surprise Prediction - The Zacks Earnings ESP model indicates that a positive Earnings ESP is a strong predictor of an earnings beat, especially when combined with a Zacks Rank of 1, 2, or 3 [9]. - Waystar currently holds a Zacks Rank of 3, which, along with the positive Earnings ESP, suggests a likelihood of beating the consensus EPS estimate [11]. Historical Performance - In the last reported quarter, Waystar met the expected earnings of $0.32 per share, resulting in no surprise [12]. - Over the past four quarters, Waystar has beaten consensus EPS estimates three times, indicating a generally favorable performance trend [13]. Conclusion - While Waystar is positioned as a compelling earnings-beat candidate, other factors may also influence stock performance post-earnings release [16].

LEHI, Utah, and LOUISVILLE, Ky., July 9, 2025 /PRNewswire/ -- Waystar Holding Corp. (Nasdaq: WAY), a provider of leading healthcare payment software, announced today that it will report financial results for the second quarter ended June 30, 2025, after market close on Wednesday, July 30, 2025. The company will discuss its financial results on a conference call at 4:30 p.m. Eastern Time that same day.A live audio webcast of the conference call will be available on Waystar's investor relations website at htt ...

Company Overview - Waystar Holding Corp. is a provider of healthcare payment software, focused on simplifying healthcare payments to enhance patient care and financial performance [4] - The company serves approximately 30,000 clients, representing over 1 million distinct providers, including 16 of the top 20 institutions on the U.S. News Best Hospitals list [4] - Waystar's platform processes over 6 billion healthcare payment transactions annually, amounting to over $1.8 trillion in gross claims, covering approximately 50% of U.S. patients [4] Leadership Changes - Waystar has appointed Aashima Gupta and Michael Roman to its Board of Directors, bringing significant expertise in AI innovation, healthcare, and enterprise growth [1][2] - Aashima Gupta, previously Global Director of Healthcare Strategy and Solutions at Google Cloud, has led initiatives in healthcare AI to improve access and efficiency [2] - Michael Roman, former CEO and Executive Chairman of 3M, has nearly 40 years of experience in strategic leadership and operational excellence, with 3M generating approximately $32 billion in annual revenue, a quarter of which is from healthcare [3] Strategic Goals - The new board members are expected to provide strategic guidance to advance Waystar's mission of simplifying healthcare payments and delivering long-term value to clients, shareholders, and team members [2] - The company aims to leverage the expertise of its new directors to enhance innovation and growth within the healthcare payment sector [2]

Summary of Waystar Holding (WAY) FY Conference Call Company Overview - **Company**: Waystar Holding (WAY) - **Industry**: Healthcare technology and software solutions - **Founded**: 2017, backed by Bain Capital - **Public Listing**: Went public approximately one year prior to the conference call Key Highlights - **Financial Performance**: - Achieved four consecutive quarters of double-digit revenue growth [8] - Adjusted EBITDA margins consistently at or above 40% [8] - Reported a year-over-year revenue growth of 14% in Q1 [49] - Adjusted Q1 EBITDA margins reported at 42% [49] - **Business Model**: - Focused on providing cloud-based software solutions for healthcare providers to streamline payment processes [10][12] - Operates in a large addressable market with an estimated annual opportunity of $15 billion [43] - Holds approximately 5% market share in hospitals and 8-9% in ambulatory sites [43] - **Client Relationships**: - Gross revenue retention rate of 97% [14][15] - Net revenue retention rate of 114% in Q1 [15] - Works with over a million providers, reaching approximately 50% of the U.S. patient population annually [22] - **Technological Advancements**: - Pioneering the use of AI and machine learning in healthcare software [14] - Launched "Altitude AI," a suite of generative AI capabilities to enhance claims processing efficiency [33][34] - Achieved an average first-pass claim acceptance rate of nearly 99% [35] Industry Context - **Challenges in Healthcare**: - The industry faces nearly $500 billion in administrative waste, with over $4 trillion spent annually on healthcare in the U.S. [26] - Staffing shortages, denial complexities, and cybersecurity concerns are prevalent issues [27] - **Market Dynamics**: - The healthcare sector is experiencing significant consolidation, with hospitals acquiring other facilities and physician networks [11] - Legacy software vendors are struggling to transition to modern cloud-based solutions, presenting an opportunity for Waystar [12] Growth Strategies - **Client Expansion**: - Plans to deepen relationships with existing clients through cross-selling and upselling additional software modules [47] - Actively pursuing new client acquisitions and expanding channel partner relationships [48] - **Acquisitions**: - Completed nine acquisitions to integrate new companies onto the Waystar platform [49] Additional Insights - **Cultural Commitment**: - Emphasizes a strong organizational culture focused on customer service and mission-driven work [4][18] - The team is passionate about simplifying healthcare payments and improving provider experiences [18] - **Integration Capabilities**: - Integrates with over 500 electronic health record and practice management systems, with more than 200 active channel partners [13][44] - **Impact on Providers**: - The software aims to reduce the complexity of billing and collections, leading to quicker payments and improved revenue visibility for providers [38][39] This summary encapsulates the key points discussed during the Waystar Holding FY Conference Call, highlighting the company's performance, market position, technological innovations, and growth strategies within the healthcare technology industry.

LEHI, Utah and LOUISVILLE, Ky., May 29, 2025 /PRNewswire/ -- Waystar (Nasdaq: WAY), a provider of leading healthcare payment software, today announced it has been named a 2025–2026 Best Company to Work For by U.S. News & World Report. In addition to this national honor, U.S. News & World Report also named Waystar a Best Company to Work For in both the Health Care and Research sector and the West region.U.S. News & World Report evaluated the 5,000 largest public companies based on employee sentiment across s ...

Shares of Waystar Holding (WAY) have gained 2.5% over the past four weeks to close the last trading session at $38.20, but there could still be a solid upside left in the stock if short-term price targets of Wall Street analysts are any indication. Going by the price targets, the mean estimate of $48.60 indicates a potential upside of 27.2%.The mean estimate comprises 10 short-term price targets with a standard deviation of $2.46. While the lowest estimate of $45 indicates a 17.8% increase from the current ...

Core Viewpoint - Waystar Holding (WAY) shows a significant improvement in earnings outlook, making it an attractive investment option as analysts continue to raise earnings estimates for the company [1][2]. Earnings Estimate Revisions - The upward trend in earnings estimate revisions reflects growing analyst optimism regarding Waystar's earnings prospects, which is expected to positively impact its stock price [2]. - For the current quarter, Waystar is projected to earn $0.32 per share, marking a substantial increase of +700% compared to the same period last year [6]. - The Zacks Consensus Estimate for the current quarter has risen by 12.99% over the last 30 days, with two estimates increasing and one decreasing [6]. - For the full year, the expected earnings per share is $1.32, indicating a year-over-year growth of +21.1% [7]. - Over the past month, five estimates for the current year have been revised upward, contributing to a 6.05% increase in the consensus estimate [7][8]. Zacks Rank and Performance - Waystar has achieved a Zacks Rank 2 (Buy), indicating strong agreement among analysts in revising earnings estimates upward [9]. - The Zacks Rank system has a proven track record, with Zacks 1 Ranked stocks averaging an annual return of +25% since 2008 [3]. - Stocks with Zacks Rank 1 (Strong Buy) and 2 (Buy) have been shown to significantly outperform the S&P 500 [9]. Stock Performance - Waystar's stock has increased by 5.9% over the past four weeks, driven by strong estimate revisions and positive analyst sentiment [10]. - There is potential for further upside in the stock, suggesting it may be a good addition to investment portfolios [10].