Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended June 30, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period From ________ to ________ Commission File Number: 001-36338 22nd Century Group, Inc. (Exact name of registrant as specified in its charter) (State or other juri ...

INVESTOR OVERVIEW June 2022 XXII CAUTIONARY NOTE ON FORWARD-LOOKING STATEMENTS | --- | |-------------------------------------------------------------------| | | | This presentation contains forward-looking statements | | concerning our business operations, and financial performance | | and conditions, as well as our plans, objectives, and | | expectations for our business operations, and financial | | performance, and conditions that are subject to risks and | | uncertainties. All statements other than thos ...

22nd Century Group, Inc. (NASDAQ:XXII) Q1 2022 Earnings Conference Call May 5, 2022 10:00 AM ET Company Participants Mei Kuo – Director of Communications and Investor Relations Jim Mish – Chief Executive Officer Mike Zercher – President and Chief Operating Officer Rich Fitzgerald – Chief Financial Officer Conference Call Participants Harrison Vivas – Cowen Brian Wright – Roth Capital Partners Jim McIlree – Dawson James Operator Welcome to the 22nd Century Group’s First Quarter 2022 Earnings Conference Call. ...

Nasdag XXII 22nd Century Group, Inc. FIRST QUARTER 2022 EARNINGS PRESENTATION May 5, 2022 ELPS YOU HELPS YOU SMOKE LESS LPS YOU MENTHOL 95% LESS NICO Nicotine is addictive. Less nicotine does NOT mean safer. All cigarettes can cause disease and death. Nicotine is addictive. Less nicotine does NOT mean safer. All cigarettes can cause disease and death Nicotine is addictive. Less nicotine does NOT mean safer. All cigarettes can cause disease and death. MENTHOL 95% LESS NICO Nicotine is addictive. Less nicotin ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended March 31, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period From ________ to ________ Commission File Number: 001-36338 22nd Century Group, Inc. (Exact name of registrant as specified in its charter) (State or other jur ...

XXII FOURTH QUARTER AND FULL YEAR 2021 EARNINGS PRESENTATION M a r c h 1, 2022 CAUTIONARY NOTE ON FORWARD-LOOKING STATEMENTS | --- | |----------------------------------------------------------------------------------------------------| | | | This presentation contains forward-looking statements | | concerning our business operations, and financial performance | | and conditions, as well as our plans, objectives, and | | expectations for our business operations and financial | | performance and conditions th ...

22nd Century Group, Inc. (NASDAQ:XXII) Q4 2021 Earnings Conference Call March 1, 2022 10:00 AM ET Company Participants Jim Mish - Chief Executive Officer Mike Zercher - President and Chief Operating Officer Mei Kuo - Director, Communications and Investor Relations Richard Fitzgerald - Chief Financial Officer Conference Call Participants Vivien Azer - Cowen and Company Jim McIlree - Dawson James Aaron Grey - Alliance Global Partners Brian Wright - Roth Capital Partners Operator Greetings, and welcome to the ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ Annual Report under Section 13 or 15(d) of the Securities Exchange Act of 1934 For the fiscal year ended December 31, 2021 or ☐ Transitional Report under Section 13 or 15(d) of the Securities Exchange Act of 1934 Commission File Number: 001-36338 22nd Century Group, Inc. (Exact name of registrant as specified in its charter) (State or other jurisdiction (IRS Employer of incorporation) Identification No.) Ne ...

22nd Century Group, Inc. (NASDAQ:XXII) Q3 2021 Earnings Conference Call November 4, 2021 10:00 AM ET Company Participants Mei Kuo – Director-Communications and Investor Relations Jim Mish – Chief Executive Officer Mike Zercher – President and Chief Operating Officer John Franzino – Chief Financial Officer Conference Call Participants Vivien Azer – Cowen Jim McIlree – Dawson James Aaron Grey – Alliance Global Partners Operator Welcome to the 22nd Century Group’s Third Quarter 2021 Earnings Conference Call. A ...

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Quarterly Period Ended September 30, 2021 ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the Transition Period From ________ to ________ Commission File Number: 001-36338 22nd Century Group, Inc. (Exact name of registrant as specified in its charter) Nevada 98-04684 ...