Nxera Pharma to Regain Full Rights to GPR52 Agonist Program for Schizophrenia
Globenewswire· 2025-12-18 23:34
Core Viewpoint - Nxera Pharma's GPR52 agonist program for schizophrenia will not be licensed by Boehringer Ingelheim, leading to the reversion of all rights and data back to Nxera [1] Group 1: GPR52 Agonist Program - NXE'149 and other GPR52 agonists were developed using Nxera's NxWave™ structure-based drug design platform to address positive, negative, and cognitive symptoms of schizophrenia [2] - A Phase 1 trial of NXE'149 showed a favorable safety profile with no severe adverse events and demonstrated dose-proportional exposure and a long half-life supporting once-daily dosing [3] - The expression of GPR52 in brain regions linked to various schizophrenia symptoms suggests NXE'149 may treat all three symptom domains, offering a potential new therapeutic option [4] Group 2: Future Plans and Financial Impact - Nxera plans to explore strategic opportunities, including a formal out-licensing process for the GPR52 program in 2026 [5] - The decision by Boehringer Ingelheim does not impact Nxera's consolidated financial results for the current accounting period [5] - CEO Christopher Cargill expressed optimism about the potential of the GPR52 program despite the setback, highlighting the strong scientific and clinical foundations established [6] Group 3: Company Overview - Nxera Pharma is focused on developing specialty medicines to meet unmet medical needs in Japan and globally, leveraging its NxWave™ discovery platform [7][10] - The company has an extensive pipeline of over 30 active programs targeting major unmet needs in areas such as obesity, neurology, and immunology [9] - Nxera employs approximately 400 people across key locations including Tokyo, London, and Basel [10]
ArrowMark Financial Corp. Announces $14.9 Million Registered Direct Offering
Globenewswire· 2025-12-18 23:30
Core Viewpoint - ArrowMark Financial Corp. has entered into a securities purchase agreement to sell 673,249 shares of common stock at a price of $22.28 per share, which is slightly above the Net Asset Value of $22.20, indicating a positive impact for current shareholders [1]. Group 1: Offering Details - The registered direct offering is expected to generate proceeds of approximately $14.99 million, excluding legal and administrative expenses [2]. - The offering is conducted under a "shelf" registration statement filed with the SEC, allowing for the sale of securities through a prospectus [3]. Group 2: Company Overview - ArrowMark Financial Corp. is a non-diversified, closed-end fund listed on NASDAQ under the symbol "BANX," with an investment objective focused on providing current income primarily through investments in regulatory capital securities of financial institutions [5].
NOTICE TO DISREGARD -- AMC Robotics Corporation
Globenewswire· 2025-12-18 23:07
Core Viewpoint - AMC Robotics Corporation has advised that recent news releases regarding the establishment of a supplier framework for robotics deployment in Japan should be disregarded [1] Group 1 - The news releases titled "AMC Robotics Establishes Supplier Framework to Enable Robotics Deployment in Japan" and "Update - AMC Robotics Establishes Supplier Framework to Enable Robotics Deployment in Japan" were issued on December 17, 2025 [1]
Willis Lease Finance Corporation Announces Partnership with Liberty Mutual Investments
Globenewswire· 2025-12-18 22:51
Investment Partnership Announcement - Willis Lease Finance Corporation (WLFC) has closed an investment partnership with Liberty Mutual Investments (LMI) to invest up to $600 million to support WLFC's credit strategy [1] - The partnership is backed by a warehouse debt facility from Bank of America N.A. and will focus on loan and loan-like engine financings, a sector WLFC pioneered in 2021 [1] Strategic Goals and Expertise - WLFC aims to accelerate the growth of its asset management business through this partnership, leveraging LMI's long-term capital and sector expertise [2] - LMI's investment emphasizes its capability to provide comprehensive financing solutions and support strong business growth in aviation finance [3] Company Overview - WLFC specializes in leasing commercial aircraft engines and related services, including maintenance and end-of-life solutions for aviation materials [4] - The company also aims to develop projects to decarbonize aviation through its Willis Sustainable Fuels initiative [4] Liberty Mutual Investments Overview - LMI is the investment arm of Liberty Mutual Group, managing over $117 billion in long-term capital globally, focusing on building enduring businesses and driving economic growth [5]
G2 Goldfields Delivers Maiden PEA for the High-Grade Oko Gold Project
Globenewswire· 2025-12-18 22:32
(All amounts are in US$) PEA Highlights: High-grade updated resource: Underpinned by G2’s updated Mineral Resource Estimate, including 1.6 Moz Au at 3.24 g/t Au (Indicated) and 1.9 Moz Au at 3.31 g/t Au (Inferred), incorporating six months of new drilling.Long life, significant production and industry-leading margins: 14-year LOM underground and open pit operation with average annual gold production of 281,000 ounces at AISC¹ of $1,137/oz Au from years 2 through 11.Attractive capital profile: Initial capita ...
Intermap Awarded Malaysian Flood Mapping Program; Indonesia ILASPP Phase 2 Evaluation Period Extended
Globenewswire· 2025-12-18 22:30
Malaysian award expands national flood forecasting footprint World Bank-funded Indonesia program advances Global insurers increasingly rely on Intermap’s elevation data to enhance flood risk and catastrophe modeling DENVER, Dec. 18, 2025 (GLOBE NEWSWIRE) -- Intermap Technologies (TSX: IMP; OTCQB: ITMSF) (“Intermap” or the “Company”), a global leader in 3D geospatial products and intelligence solutions, today announced an update on Indonesia, Malaysia, insurance and guidance. IndonesiaThe World Bank-funded I ...
TransAlta Provides Notice to Mothball Sheerness Unit 1
Globenewswire· 2025-12-18 22:22
CALGARY, Alberta, Dec. 18, 2025 (GLOBE NEWSWIRE) -- Alberta Power (2000) Ltd., a subsidiary of TransAlta Corporation (TransAlta or the Company) (TSX: TA) (NYSE: TAC), provided notice to the Alberta Electric System Operator on December 18, 2025, that Sheerness Unit 1 will be temporarily mothballed effective April 1, 2026, for a period of up to two years. TransAlta maintains the flexibility to return the mothballed unit to service when market fundamentals or contracting opportunities are secured. The unit wil ...
BlackRock® Canada Announces Changes to Certain ETFs
Globenewswire· 2025-12-18 22:19
TORONTO, Dec. 18, 2025 (GLOBE NEWSWIRE) -- BlackRock Asset Management Canada Limited (“BlackRock Canada”), an indirect, wholly-owned subsidiary of BlackRock, Inc. (“BlackRock”) (NYSE: BLK) is announcing that effective on December 18, 2025, the annual management fees of the following iShares exchange-traded funds (“iShares Funds”) will change as follows: NameTickerFormer Management Fee(1)New Management Fee(1)iShares Core Balanced ETF PortfolioXBAL0.18%0.17%iShares Core Conservative Balanced ETF Portfolio<td ...
TeraWulf and Fluidstack Announce Successful Pricing of Project Financing for 168 MW HPC Compute Joint Venture
Globenewswire· 2025-12-18 22:17
Core Insights - TeraWulf Inc. has successfully priced project-level financing for a 168 MW high-performance computing (HPC) joint venture at its Abernathy, Texas campus, reinforcing its strategic partnership with Fluidstack and expanding AI demand [1][2] Financing and Project Details - The financing will support the development of a next-generation, liquid-cooled AI data center with a gross power capacity of up to 240 MW, including 168 MW for critical IT load, under a long-term hosting structure with investment-grade credit support [2] - Proceeds from the financing will be utilized for construction, establishing required reserves, and ensuring the facility is on track for commissioning in the second half of 2026 [3] Partnership and Market Position - The Abernathy project exemplifies the evolving partnership between TeraWulf and Fluidstack, focusing on repeatable site design, disciplined capital formation, and efficient delivery of large-scale AI infrastructure [4] - The demand for HPC compute is growing rapidly, necessitating multiple sourcing paths and diverse infrastructure partners, positioning the Abernathy campus as a competitive solution due to its scale and advanced design [5] Capacity Expansion and Market Outlook - The joint venture retains the ability to expand beyond the initial 168 MW phase, leveraging existing infrastructure to support incremental, high-density deployments as market demand scales [6] - TeraWulf and Fluidstack have established themselves as early leaders in structuring and financing AI compute infrastructure, with expectations to deploy an additional 250 MW to 500 MW of HPC capacity annually, having already secured over 500 MW to date [7][8] Leadership Commentary - TeraWulf's CEO emphasized that the financing is a significant step in scaling a platform designed for growth, validating their early focus on adaptable sites and relationships as the AI market evolves [9] - Fluidstack's CEO expressed satisfaction in strengthening their partnership with TeraWulf through this financing, aiming to deliver more next-generation capacity in future joint ventures [9]
North American Construction Group Strengthens its Presence in Western Australia with the Acquisition of Iron Mine Contracting, a Diversified Mining Services Contractor
Globenewswire· 2025-12-18 22:05
NACG also Provides Year-End Business Updates on Infrastructure, Fleet Optimization and 2026 OutlookACHESON, Alberta, Dec. 18, 2025 (GLOBE NEWSWIRE) -- North American Construction Group Ltd. (“NACG” or the “Company”) (TSX:NOA/NYSE:NOA) today announced that it has entered into a definitive share purchase agreement to acquire Iron Mine Contracting (“IMC”), a privately owned Western Australian diversified mining services contractor. The acquisition is valued at approximately $115 million (“the Transaction”). Co ...