Core Insights - Rein Therapeutics has received orphan drug designation from the European Medicines Agency (EMA) for its lead drug candidate LTI-03, aimed at preserving lung function in patients with idiopathic pulmonary fibrosis (IPF) [1][2][6] Group 1: Drug Designation and Regulatory Impact - The orphan drug designation follows a positive opinion from the EMA's Committee for Orphan Medicinal Products (COMP), highlighting the seriousness of IPF and the need for new treatment options [2] - Orphan drug designation in the EU provides regulatory incentives such as reduced development fees, potential market exclusivity, and enhanced development efficiency [4] Group 2: Disease Context and Treatment Landscape - IPF is a rare, progressive lung disease characterized by irreversible scarring of lung tissue, leading to declining lung function and respiratory failure, with existing treatments offering poor outcomes [3] - The EMA's decision was supported by preclinical data showing improved survival and lung function, indicating a clinically relevant advantage of LTI-03 over authorized products [5] Group 3: Company Overview and Future Prospects - Rein Therapeutics is a clinical-stage biopharmaceutical company focused on developing first-in-class therapies for orphan pulmonary and fibrosis indications, with LTI-03 being a synthetic peptide targeting alveolar epithelial cell survival and inhibiting profibrotic signaling [7] - The company also has a second product candidate, LTI-01, which has completed Phase 1b and Phase 2a clinical trials for loculated pleural effusions and has received orphan drug designation in both the U.S. and EU [7]

Certification affirms compliance with international cyber-resilience standards for onboard computer-based systems SINGAPORE, Jan. 20, 2026 (GLOBE NEWSWIRE) -- iOThree Limited ("iO3" or the "Company") (NASDAQ: IOTR), a pioneering provider of digital solutions for the maritime industry, announces that V.Secure, its maritime cybersecurity system with a managed Security Operations Center (SOC), has been granted IACS UR E27 Type Approval by RINA, the international classification society. This certification confi ...

Tuesday, Feb. 3, 2026 at 4:30 p.m. Eastern TimeFREMONT, Calif., Jan. 20, 2026 (GLOBE NEWSWIRE) -- Enphase Energy, Inc. (NASDAQ: ENPH), a global energy technology company, announced today that it will host a conference call and webcast on Tuesday, Feb. 3, 2026 at 4:30 p.m. Eastern Time to discuss its fourth quarter and full year 2025 financial results for the period ended Dec. 31, 2025. The live webcast can be accessed on the Enphase Energy Investor Relations website at investor.enphase.com, and a recorded v ...

Core Insights - Alignment Health has appointed Adnan Mansour as chief digital officer to enhance its technology and information functions, aiming for scalable growth and innovation [1][2][4] Company Strategy - The appointment of Mansour is part of Alignment's strategy to fast-track growth over the next five years, focusing on investing in people and technology [4] - Alignment Health reported a health plan membership of approximately 275,300 as of January 1, representing a 31% year-over-year growth [4] Leadership and Experience - Mansour brings extensive experience from his previous role as senior vice president and chief information officer at Optum Insight, where he led global IT and engineering teams [2][5] - He has a strong background in embedding artificial intelligence into healthcare systems and has overseen over 2,000 engineers and AI experts [5] Technology and Innovation - As chief digital officer, Mansour will scale Alignment's digital capabilities and enhance the AI-powered AVA platform, which has been delivering real-time insights for over a decade [3][4] - Mansour has previously driven AI innovation at Change Healthcare, launching over 20 production AI applications [5] Company Mission - Alignment Health aims to empower seniors to age well and live vibrant lives, focusing on high-quality, low-cost care for its Medicare Advantage members [7]

Core Insights - Agereh Technologies Inc. has launched HeadCounter™, an AI-enabled, wireless device designed to provide real-time, anonymous insights into passenger movement, congestion, and behavior in transportation environments [1][2]. Company Overview - Agereh Technologies Inc. is a Canadian-based company specializing in artificial intelligence and advanced technology solutions for the transportation industry, focusing on enhancing efficiency and optimizing operations [6]. Product Features - HeadCounter™ can accurately count passengers, track movement patterns, and measure body temperatures, incorporating integrated thermal-pattern sensing for crowd density and safety insights [2]. - The device operates on both public and private cellular networks, offering up to one year of rechargeable battery life or continuous operation when plugged in, allowing for flexible deployment without extensive infrastructure [3]. Market Context - With global passenger traffic exceeding 9.5 billion travelers, transportation hubs are under pressure to improve operational efficiency, reduce congestion, and unlock new revenue opportunities using real behavioral data [5]. - Retail, dining, and passenger services contribute to 40-50% of total airport revenue, highlighting the importance of visibility into passenger movement for enhancing passenger experience and commercial performance [4].

BERKELEY, Calif., Jan. 20, 2026 (GLOBE NEWSWIRE) -- Rigetti Computing India P L, a wholly owned subsidiary of Rigetti Computing, Inc. (Nasdaq: RGTI) (“Rigetti” or the “Company”), a pioneer in full-stack quantum-classical computing, today announced that it has received an $8.4 million purchase order to deliver a 108-qubit quantum computer to the Centre for Development of Advanced Computing (C-DAC), India’s premier R&D organization of the Ministry of Electronics and Information Technology. The system will be ...

VANCOUVER, British Columbia, Jan. 20, 2026 (GLOBE NEWSWIRE) -- GoGo AI Network Inc. (CSE: GOGO) (OTC: GOGAF) (FSE: 4E9) (the “Company” or “GoGo”) is pleased to provide a corporate update on a meaningful commercial milestone achieved by Algo8, one of GoGo’s core portfolio companies. Algo8, an enterprise industrial artificial intelligence company focused on manufacturing, infrastructure, and large-scale operational systems, has commenced Phase 1 implementation of a multi-plant digital transformation initiativ ...

DAVOS, Switzerland, Jan. 20, 2026 (GLOBE NEWSWIRE) -- Sumit Kapur, Chief Executive Officer of Zapata Quantum Inc. (OTC: ZPTA) (“Zapata”, “Zapata Quantum” or the “Company”), spoke today to global business and technology leaders in Davos, Switzerland. In his remarks on two separate panels, he outlined why the next phase of quantum computing will be defined not by hardware milestones alone, but by the ability to build, validate, and deploy reliable quantum applications. “It’s a privilege to be part of the Davo ...

BOCA RATON, Fla., Jan. 20, 2026 (GLOBE NEWSWIRE) -- LIXTE Biotechnology Holdings, Inc. (“LIXTE” or the “Company”) (Nasdaq: LIXT), a clinical-stage pharmaceutical company advancing LB-100, a first-in-class inhibitor of protein phosphatase 2A (PP2A), today announced the Company will participate at the DealFlow Discovery Conference in Atlantic City, New Jersey, January 28-29, 2026. Geordan Pursglove, LIXTE’s Chief Executive Officer, will conduct one-on-one meetings with investors during the conference. The con ...

Core Insights - Fusemachines Inc. announced a follow-on equity investment of USD $1 million from Consilium Investment Management to support product portfolio expansion and client base scaling [1][2][3] Investment Details - The investment was structured as a private investment in public equity (PIPE) and will be utilized for product innovation in retail and real estate, as well as for increasing sales and marketing efforts [2] Company Strategy - The CEO of Fusemachines emphasized that the investment reflects confidence in the company's strategy and execution, enabling accelerated product development and broader client reach [3] - The company aims to execute its 2026 growth strategy focusing on vertical product innovation, client adoption, global partnerships, and strategic acquisitions [3] Company Background - Founded in 2013, Fusemachines is dedicated to democratizing AI, providing enterprise AI products and services to various industries including retail, manufacturing, and government [5] - The company operates globally with offices in North America, Asia, and Latin America, offering a suite of AI solutions to organizations of all sizes [5] Recent Developments - In October 2025, Fusemachines launched a Global Reseller Network to enhance access to its AI products [8] - The company formed a strategic partnership with RentRedi in December 2025 to integrate AI solutions into the real estate sector [8]