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X @Token Terminal ๐Ÿ“Š
โ›“๏ธ๐ŸŒ @ethereum GDP is close to all-time highs.Key takeaway for app developers: you can build a great business on top of Ethereum. https://t.co/eW67dMeYft ...
X @Token Terminal ๐Ÿ“Š
RT Token Terminal ๐Ÿ“Š (@tokenterminal)Historical data on Ethereumโ€™s top 10 GDP contributors reveals a structural shift whereby NFT marketplaces (OpenSea & LooksRare) have been replaced by stablecoin issuers as the leading drivers of the Ethereum economy. https://t.co/xD9AuQFKqX ...
Timberland Bancorp: Strong Loan Book Means The Stock Is A Buy
Seeking Alphaยท 2025-07-09 14:30
I have had a long position in Timberland Bancorp (NASDAQ: TSBK ) and have been following the stock for several years now . Iโ€™m attracted to the bankโ€™s robust balance sheet, its loan book with a low amount of loans past due, andHe is the leader of the investment group European Small Cap Ideas which offers exclusive access to actionable research on appealing Europe-focused investment opportunities not found elsewhere. The a focus is on high-quality ideas in the small-cap space, with emphasis on capital gains ...
X @Lookonchain
Lookonchainยท 2025-07-09 14:14
GMX(@GMX_IO) was hacked for $42M.Currently, the hacker has bridged $9.65M to #Ethereum and exchanged them into $DAI and $ETH.https://t.co/mnWxs3za6e https://t.co/ursqBA71dZ ...
X @Token Terminal ๐Ÿ“Š
RT Milk Road (@MilkRoadDaily)Ethereumโ€™s FDV has consistently outrun its ecosystem TVLThatโ€™s not just market optimism, itโ€™s a bet on what's coming https://t.co/ywLwY7bQVP ...
Krystal Biotech (KRYS) Update / Briefing Transcript
2025-07-09 13:30
Summary of Crystal Biotech's Conference Call on KB801 Company and Industry Overview - **Company**: Crystal Biotech - **Industry**: Biotechnology, specifically focusing on gene therapy for ophthalmic conditions, particularly neurotrophic keratitis (NK) Key Points and Arguments 1. **First Patient Dosed**: The first patient has been dosed in the EMERALD-one Phase 1/2 study evaluating KB801 for the treatment of neurotrophic keratitis [2][5][22] 2. **Current Treatment Landscape**: NK is a rare, degenerative disease with only one FDA-approved therapy, Oxervate, which requires intensive dosing (six times daily) and has limitations such as rapid protein clearance and associated eye pain [7][9][10] 3. **Market Opportunity**: The estimated number of U.S. patients with an NK claim in 2024 is projected to be 68,000, representing a 115% increase from 2020 [7] 4. **KB801 Advantages**: KB801 aims to provide a more consistent nerve growth factor (NGF) exposure with a reduced treatment burden, potentially dosed once or twice weekly compared to Oxervate's six times daily regimen [10][24] 5. **Clinical Program Design**: EMERALD-one is a double-masked, randomized, placebo-controlled study involving up to 27 adult subjects with moderate to severe NK [22][23] 6. **Safety and Efficacy Focus**: The primary focus of the study is on the safety and tolerability of KB801, with secondary endpoints assessing efficacy through corneal defect closure and corneal sensitivity [23][24] 7. **Regulatory Confidence**: The company expresses confidence in obtaining an accelerated pathway for approval due to the existing knowledge from Oxervate and the favorable dosing regimen of KB801 [24][40][41] 8. **Platform Technology**: The HSV-1 based gene delivery platform is highlighted as versatile, with applications in multiple tissues (skin, lung, eye) and the potential for various genetic therapies [5][12][28] 9. **Future Pipeline**: The company has a diversified pipeline with ongoing programs in oncology, aesthetics, and skin, alongside KB801 and KB803, which are both in clinical stages [27][28] Additional Important Content 1. **Preclinical Data**: Preclinical studies indicate that KB801 can effectively transduce corneal epithelial cells, leading to sustained NGF production without cytotoxicity [15][18][19] 2. **Market Dynamics**: The company is actively engaging with key opinion leaders (KOLs) and clinical sites to facilitate patient enrollment, indicating a strong demand for new treatments in this space [79] 3. **Patient Compliance Issues**: The challenges of patient adherence to the current treatment regimen (Oxervate) are emphasized, with many patients unable to maintain the required dosing frequency [94] 4. **Potential for Faster Wound Closure**: There is optimism that KB801 could lead to faster wound closure compared to existing therapies, although the exact duration of treatment will be evaluated based on clinical data [76][81] 5. **Regulatory Interactions**: The company has had positive interactions with the FDA, which has provided feedback on the study design and expressed understanding of the product's profile [100][101] This summary encapsulates the critical insights from the conference call, highlighting the strategic direction of Crystal Biotech and the potential impact of KB801 on the treatment of neurotrophic keratitis.
X @Token Terminal ๐Ÿ“Š
ICYMI: @Ripple's RLUSD on @ethereum surpassed $400m in supply. https://t.co/3xR3rdCe99 ...
X @TylerD ๐Ÿง™โ€โ™‚๏ธ
Funding & Strategy - BTCS Inc is increasing its funding target to $225 million [1] - The funding is aimed to accelerate its Ethereum (ETH) accumulation strategy [1] - The strategy focuses on scaling $ETH per share [1] Market Outlook - The crypto regulatory environment is maturing [1] - There is increased institutional focus on Ethereum [1]
BioVie Announces Data Highlighting Bezisterimโ€™s Potential to Slow or Reverse Biological Aging and Neurodegeneration Featured as a Keynote Talk at the 7th World Aging and Rejuvenation Conference
Globenewswireยท 2025-07-09 12:00
CARSON CITY, Nev., July 09, 2025 (GLOBE NEWSWIRE) -- BioVie Inc. (NASDAQ: BIVI) ("BioVie" or the "Company"), a clinical-stage company developing innovative drug therapies for the treatment of neurological and neurodegenerative disorders and advanced liver disease, presented "Bezisterim Epigenetic Effects on Aging and Neurodegeneration" at the 7th World Aging and Rejuvenation Conference (ARC-2025) taking place in Vienna, Austria, July 9th โ€“10th, 2025. Unlike historical approach to Alzheimer's Disease (AD) tr ...
Galectin Therapeutics Announces New $10 Million Credit Line from Richard E. Uihlein, Sufficient to Cover Expected Expenditures Through June 2026
Globenewswireยท 2025-07-09 12:00
This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements relate to future events or future financial performance, and use words such as "may," "estimate," "could," "expect", "look forward", "believe", "hope" and others. They are based on NORCROSS, Ga., July 09, 2025 (GLOBE NEWSWIRE) -- Galectin Therapeutics Inc. (NASDAQ:GALT), the leading developer of galectin-3-targeted therapeutics for patients with metabolic dysfun ...