Group 1 - The global incidence of prostate cancer is projected to rise from 1.4 million new cases in 2020 to 2.9 million by 2040, with deaths increasing from 375,000 to nearly 700,000 in the same period [2] - In the United States, approximately 2.0419 million new cancer cases are expected in 2025, with prostate cancer accounting for 30% of male cases, an increase of 1 percentage point from 2024 [2] - In China, new prostate cancer cases among men reached 134,200 in 2022, ranking sixth among male malignancies, with its proportion rising from 3.5% in 2016 to 5.3% in 2022, indicating a significant growth rate [3] Group 2 - The treatment options for prostate cancer primarily include drug therapy, surgical treatment, and radiation therapy, indicating a diverse market for related pharmaceutical companies [3] - Companies such as Aoxiang Pharmaceutical, which produces prostaglandin products, reported a revenue of 22.08 million yuan in 2024, a year-on-year decline of 16.56%, with a gross margin of 76.21% despite an 8.75 percentage point decrease from 2023 [3][4] - The Hong Kong-listed company, Yuan Da Pharmaceutical, has developed a targeted PSMA diagnostic drug, TLX591-CDx, which achieved nearly $517 million in sales in 2024 and has completed Phase III clinical trials in China [4]

Core Viewpoint - The article discusses the diagnosis of former President Biden with malignant prostate cancer, which has metastasized to the bones, and highlights the implications of his Gleason score of 9, indicating a highly aggressive form of cancer [3][6]. Group 1: Diagnosis and Medical Insights - Biden's cancer diagnosis was confirmed after a small nodule was found on his prostate, leading to further examinations [4]. - The Gleason score of 9 signifies one of the most aggressive forms of prostate cancer, as explained by medical experts [7]. - The National Institutes of Health (NIH) reports that prostate cancer is the most common cancer among men in the U.S. and the second leading cause of cancer death [7]. Group 2: Treatment and Prognosis - Despite the aggressive nature of the cancer, it appears to be responsive to hormone therapy, allowing for effective management of the disease [3][7]. - Treatment plans will be personalized and may include hormone therapy, chemotherapy, or radiation [7]. - The five-year relative survival rate for prostate cancer is approximately 98%, indicating a generally favorable prognosis for treated patients [7]. Group 3: Reactions and Support - Former President Trump expressed his condolences and well wishes for Biden's recovery [9]. - Vice President Harris and former President Obama also shared their support and prayers for Biden, emphasizing his strength and resilience [10][12].

Group 1 - Prostate cancer is the second most common tumor type among men globally, with approximately 1 in 9 men diagnosed in their lifetime [1][2] - President Biden has been diagnosed with malignant prostate cancer, with cancer cells having spread to his bones, and his Gleason score is reported to be 9, indicating a highly aggressive form of the disease [1][2] - The treatment options for prostate cancer are diverse and should be personalized based on individual patient circumstances, potentially involving a combination of therapies such as hormone therapy, chemotherapy, or radiation [3] Group 2 - Recent advancements in the development of new prostate cancer drugs have been made, with the FDA approving enzalutamide (brand name: Xtandi) for a new indication in November 2023, marking it as the first approved treatment for high-risk non-metastatic castration-sensitive prostate cancer [3] - The five-year survival rate for metastatic prostate cancer in China is reported to be less than 50%, with 20%-30% of patients already having metastasis at the time of initial diagnosis [2] - Prostate cancer typically has a slower progression compared to other malignancies, allowing patients to maintain a relatively normal life and quality of life even in high-risk cases [3]

Core Points - Former President Biden has been diagnosed with malignant prostate cancer that has metastasized to the bones [1] - The Gleason score for Biden's cancer is 9, indicating a highly aggressive form of prostate cancer [2] - Despite the severity, the cancer appears to be responsive to hormone therapy, allowing for effective management of the disease [1][2] Medical Insights - Prostate cancer is the most common cancer among men in the U.S. and the second leading cause of cancer death [2] - The Gleason score is a grading system that assesses the aggressiveness of prostate cancer, with a score of 9 being classified as highly aggressive [2] - Factors such as blood prostate-specific antigen levels, imaging tests, and biopsy results are crucial for determining the cancer's behavior and optimal treatment [2] - The five-year relative survival rate for prostate cancer is approximately 98% [2] Treatment Considerations - Treatment plans for high-risk prostate cancer patients can be personalized and may include hormone therapy, chemotherapy, or radiation [2] - New hormone therapies and chemotherapy options have shown impressive efficacy in extending patient survival [2] Responses from Public Figures - Former President Trump expressed sadness over Biden's diagnosis and extended best wishes for a speedy recovery [4] - Vice President Harris also conveyed her support, highlighting Biden's resilience [4] - Former President Obama shared his concern and confidence in Biden's ability to overcome this challenge [5]

来源丨央视新闻 SFC 据央视新闻报道，当地时间5月1 8日，根据美国前总统拜登办公室发布的一份声明， 拜 登 被 确诊患有恶性前列腺癌，癌细胞已扩散至骨骼。 美国前总统拜登 图\新华社 声明指出，拜登上周因泌尿系统症状加剧而新发现一个前列腺结节，医生在进一步评估后于 1 6日诊断拜登患有前列腺癌。 声明称，虽然这是一种更具侵袭性的癌症，但这种癌症似乎对激素敏感，因此可以进行有效 治疗，拜登及其家人正在与他的医生共同探讨治疗方案。 据央视新闻报道，当地时间5月1 8日， 美国现任总统特朗普在其社交媒体平台"真实社交"上 发文表示，他和其妻子对于美国前总统拜登最近的病情诊断深感悲痛，并向拜登及其家人致 以最温暖和最美好的祝愿。 特朗普祝愿拜登早日康复。 本期编辑 黎雨桐 21君荐读 邓超、孙俪工作室，严正声明！ "绝不妥协"！胖东来连发视频，高管哽咽落泪！柴怼怼账号内容已被清空 双双公告！A股重大资产重组 ...