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超300人团队共同完成!中国科学家十项成果给大脑绘高清地图
第一财经· 2025-07-11 09:39
Core Viewpoint - Recent collaborative achievements by Chinese scientists have created a "high-definition map" of the brain, marking significant progress in the "whole brain mesoscopic neural connectivity map" scientific initiative, which aims to understand brain structure and function across various species, including primates and humans [1][5][6]. Group 1: Scientific Achievements - A series of ten research papers were published in prestigious journals, showcasing the collaborative efforts of over 300 researchers from more than 30 institutions, both domestic and international [1][6]. - The research covers key species including reptiles, birds, rodents, non-human primates, and humans, integrating multimodal data such as transcriptomics and connectomics [9]. - The results aim to establish a research framework that transitions from structural analysis to functional understanding of the brain, providing new perspectives and methodologies for brain research [9]. Group 2: Research Goals and Timeline - The initiative aims to complete the mesoscopic neural connectivity map for mice by 2025 and for macaques by 2035, focusing on non-human primates and human brain mapping [6][7]. - An international alliance for mesoscopic brain mapping research is being formed, with participation from over 20 countries and nearly 100 scientists, emphasizing the importance of global collaboration [7][8]. Group 3: Technical Challenges and Innovations - The research involves identifying various cell types and their connections, requiring high-resolution imaging at the micrometer level to understand the network structure of the brain [8][11]. - New technologies have been developed to enhance the tracking of specific cell types and their connections, marking a significant advancement in primate brain science [9][10]. - The complexity of tracking individual neurons necessitates extensive collaboration and time investment, highlighting the challenges faced in this field [10][11].