Group 1 - The 2025 Pujiang Innovation Forum was held in Shanghai from September 20 to 22, focusing on building an open and cooperative global technology community and showcasing cutting-edge technological achievements in future industries [1][2] - The forum launched a technology supply-demand "fast track" between enterprises and research teams, with the 2025 InnoMatch Technology Transfer Conference releasing over 10,000 technology demands and attracting over 20 billion yuan in funding [1][4] - The 2025 WeStart Venture Capital Conference aimed to connect entrepreneurial projects with capital, fostering a hard technology investment ecosystem [1][6] Group 2 - A series of cutting-edge technologies were presented at the forum, including quantum technology, controllable nuclear fusion, brain-machine interfaces, and silicon photonics, highlighting the integration of basic research and industrial application [2][3] - The establishment of the International Primate Mesoscopic Brain Atlas Alliance was announced, aiming to create detailed brain maps to understand brain functions and tackle major brain diseases [2] Group 3 - The Shanghai Silicon Photonics Concept Verification Platform was launched to support the industrialization of silicon photonics technology, facilitating the verification of technological and market feasibility [3] - The platform will collaborate with various entities, including future industry funds and specialized technology transfer organizations, to enhance project incubation and resource integration [3] Group 4 - The "Transformation Clinic" at the 2025 InnoMatch Technology Transfer Conference provided a one-stop service for technology transfer, connecting enterprises with experts in various fields for personalized consulting [4][5] - Since its inception, the "Transformation Clinic" has facilitated 374 projects, with over 50 selected for commercial potential, resulting in contracts exceeding 300 million yuan [5] Group 5 - The 2025 WeStart Venture Capital Conference introduced a platform for connecting entrepreneurial projects with capital, emphasizing the importance of early-stage investments in hard technology sectors [6][7] - Shanghai Guotou Company is focusing on key sectors such as controllable nuclear fusion, artificial intelligence, and quantum computing, leveraging over 120 billion yuan in social capital through its fund matrix [7]

Core Insights - The establishment of the "International Primate Mesoscopic Brain Mapping Alliance" marks the official launch of systematic global collaboration in primate brain mapping research [2][3]. Group 1: Alliance Formation and Objectives - The alliance was formed during the 2025 International Symposium on Mesoscopic Brain Mapping held at the Pujiang Innovation Forum on September 20, where a signing ceremony for member institutions took place [2]. - The white paper released by the alliance outlines a ten-year plan for the core tasks of the brain mapping grand scientific initiative, aiming to create a global, open collaborative research network [5]. Group 2: Milestones and Research Goals - The white paper sets three major milestones in primate brain mapping research: 1. To create the first comprehensive, cell-type-specific mesoscopic connectome of the primate brain, revealing the neural network architecture underlying cognitive functions [6]. 2. To establish a single-cell resolution, multi-omics primate brain cell atlas by integrating data from single-cell and spatial transcriptomics, proteomics, and epigenomics, characterizing cellular diversity across the lifespan [6]. 3. To map the fine three-dimensional structure of synapses, identifying synaptic features related to cognitive functions and revealing synaptic microstructures associated with aging and brain diseases [6]. Group 3: International Collaboration and Membership - The alliance has gathered 118 members from 25 countries and regions, including China, the United States, the United Kingdom, Australia, India, Japan, and South Korea, representing over 60 top global universities and research institutions [7]. - Notable member institutions include the Chinese Academy of Sciences, Fudan University, Tsinghua University, Harvard Medical School, and the Max Planck Society [7]. - The alliance also includes several international synchrotron radiation centers, such as Japan's SPring-8 and Thailand's SLRI [8].

Group 1 - Xi Jinping emphasized the importance of cultural confidence and encouraged filmmakers to create works that reflect the spirit of the times and express the voices of the people [1][3][4] - The global dialogue initiative proposed by Xi Jinping received positive evaluations from foreign guests at the ministerial meeting, highlighting its significance in promoting peace and development [5][6] Group 2 - China's automotive industry reported multiple economic indicators achieving double-digit growth year-on-year in the first half of the year [12] - The China Export-Import Bank provided over 610 billion yuan in new loans to the foreign trade sector in the first half of the year, with a nearly 20% year-on-year increase in loans to small and micro foreign trade enterprises [15]

Core Viewpoint - Recent collaborative achievements by Chinese scientists have created a "high-definition map" of the brain, marking significant progress in the "whole brain mesoscopic neural connectivity map" scientific initiative, which aims to understand brain structure and function across various species, including primates and humans [1][5][6]. Group 1: Scientific Achievements - A series of ten research papers were published in prestigious journals, showcasing the collaborative efforts of over 300 researchers from more than 30 institutions, both domestic and international [1][6]. - The research covers key species including reptiles, birds, rodents, non-human primates, and humans, integrating multimodal data such as transcriptomics and connectomics [9]. - The results aim to establish a research framework that transitions from structural analysis to functional understanding of the brain, providing new perspectives and methodologies for brain research [9]. Group 2: Research Goals and Timeline - The initiative aims to complete the mesoscopic neural connectivity map for mice by 2025 and for macaques by 2035, focusing on non-human primates and human brain mapping [6][7]. - An international alliance for mesoscopic brain mapping research is being formed, with participation from over 20 countries and nearly 100 scientists, emphasizing the importance of global collaboration [7][8]. Group 3: Technical Challenges and Innovations - The research involves identifying various cell types and their connections, requiring high-resolution imaging at the micrometer level to understand the network structure of the brain [8][11]. - New technologies have been developed to enhance the tracking of specific cell types and their connections, marking a significant advancement in primate brain science [9][10]. - The complexity of tracking individual neurons necessitates extensive collaboration and time investment, highlighting the challenges faced in this field [10][11].

Core Insights - Chinese scientists have released a series of ten research achievements that provide a "high-definition map" of the human brain, with five of these achievements led by scientists from Shanghai [1][3] - The "Whole Brain Mesoscopic Neural Connectivity Atlas" project aims to complete the mapping of mouse brains by 2025 and macaque brains by 2035, focusing on non-human primates and human brain connectivity [3][4] - The project involves over 300 researchers from more than 30 institutions, showcasing international collaboration in brain science [1][3] Group 1: Research Achievements - The ten research outcomes cover key species including reptiles, birds, rodents, non-human primates, and humans, integrating multimodal data such as transcriptomics and connectomics [6] - The research establishes a framework for understanding brain structure and function, moving from "circuit analysis" to "disease decoding" [6] - The achievements include the development of a multi-omics enhancer prediction system and a toolset for identifying specific neuron types in macaque brains, marking a new phase in primate brain science [6][7] Group 2: Project Goals and Collaboration - The project aims to establish an "International Primate Mesoscopic Brain Atlas Alliance" to enhance global cooperation in brain mapping research [4][5] - The alliance has attracted interest from over 20 countries and nearly 100 scientists, emphasizing the importance of international collaboration in understanding human brain function and disease mechanisms [5] - The project is supported by the Shanghai Municipal Science and Technology Commission and has received approval from the Ministry of Science and Technology [4][5] Group 3: Technical Challenges - Tracking neural connections requires significant time and effort, with each cell needing multiple hours of work for accurate tracing [7][8] - The project aims to identify all cell types in primates within five years, followed by mapping their connections, which is expected to take around ten years for macaque neural connectivity [8]