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新血检工具可提前识别HPV相关头颈癌
Ke Ji Ri Bao· 2025-09-17 23:00
为验证"HPV-DeepSeek"能否在癌症确诊前多年实现早期识别,研究团队对来自马萨诸塞州布莱根生物 银行的56份样本进行了测试,其中28份来自被确诊为HPV相关头颈癌的患者,另外28份来自健康对照 者。 结果显示,"HPV-DeepSeek"在28例癌症患者中的22例血液样本中检测到了HPV肿瘤DNA,其中最早一 例阳性样本采集于确诊前7.8年,而所有对照样本的检测结果均为阴性,显示出高度特异性。通过引入 机器学习技术,研究团队进一步将检测灵敏度提高至可识别28例癌症中的27例,包括确诊前10年采集的 样本。 目前,研究团队正基于美国国家癌症研究所"前列腺癌、肺癌、结直肠癌和卵巢癌筛查试验"中收集的数 百份样本开展进一步研究,以验证这一成果。 美国麻省总医院百瀚医疗系统科学家开展的一项最新研究发现,他们研制的血液检测工具"HPV- DeepSeek"能在症状出现前10年识别出与人乳头瘤病毒(HPV)相关的头颈癌,从而为患者提供更早的 治疗干预,改善其预后和生活质量。相关研究成果发表于新一期《国家癌症研究所杂志》。 在美国,70%的头颈癌由HPV引起,且发病率逐年上升。与HPV引起的宫颈癌不同,目前尚无针对 ...
《益生菌及制品的检验方法》国家团体标准在京发布
Zhong Guo Jing Ji Wang· 2025-09-15 08:35
Core Viewpoint - The release of the national group standard for probiotics and related products marks a significant advancement in the regulatory framework, aiming to enhance quality control and international competitiveness in the probiotic industry [1][5][6] Group 1: Standard Overview - The standard, titled "Testing Methods for Probiotics and Products," was officially launched at the Fourth World Frontier Technology Conference in Beijing [1] - It encompasses technical specifications, quality requirements, and testing methods throughout the entire production and sales chain of probiotics, including strain identification, viable count determination, contamination detection, stability testing, and alignment with international standards [1] - The standard mandates that probiotic strains must have a clear taxonomic status and scientific naming, along with rigorous efficacy validation and safety assessment [1] Group 2: Technological Integration - The standard integrates advanced detection technologies such as whole genome sequencing (WGS) and flow cytometry, enhancing the scientific rigor of the testing methods [1] - It emphasizes the deep integration of biotechnology and testing methods, which is expected to promote collaboration between academia and industry, facilitating technological upgrades in the sector [3] Group 3: International Standards Reference - The drafting process of the standard extensively referenced international standards and guidelines from organizations such as the Codex Alimentarius Commission (CAC), ISO, FDA, and EFSA, ensuring strong scientific validity and operability [5] - The standard is designed to align with existing national food safety standards in China, which is anticipated to significantly boost the international competitiveness of Chinese probiotic products [5] Group 4: Implementation Timeline - The standard is set to be officially implemented in the near future, marking a new phase for the probiotic industry in China [6]