Group 1 - The core viewpoint of the news highlights the positive impact of upgraded innovative drug policies and domestic medical device substitution, leading to a significant increase in the vaccine ETF (159643) by over 5.3% [1] - The 11th batch of national centralized procurement policies shows an optimization trend, moving away from simple lowest price references to a "low-price declaration" system, requiring companies to commit to not pricing below cost [1] - The policy maintains the principle of "no centralized procurement for new drugs," excluding products with annual procurement amounts below 100 million yuan, while enhancing quality supervision and targeted inspections of low-priced selected drugs [1] Group 2 - The innovative drug sector is entering a stage of realizing results, with significant R&D progress, particularly in emerging markets, indicating potential for companies expanding internationally [1] - Certain sub-sectors, such as insulin and orthopedics, have seen the impact of centralized procurement clear up, suggesting a new growth phase ahead [1] - The current valuation of the pharmaceutical sector stands at 29.88 times (TTM), with a premium of 153.54% relative to the CSI 300, and a year-to-date increase of 16.59%, outperforming the market by 13.45 percentage points [1]