Core Viewpoint - The research team at the Tianjin Institute of Industrial Biotechnology has made significant advancements in the bioconversion of lignin into microbial oils and proteins, addressing the challenges of lignin degradation and high-value utilization [5][7]. Summary by Sections Research Breakthroughs - The team successfully developed a genetically engineered strain, Curvularia clavata M6, which efficiently degrades lignin and simultaneously synthesizes oils and proteins. This was achieved by combining genome editing technology with high-throughput screening methods [5][6]. - The engineered strain M6 exhibited a 75% increase in laccase activity, reaching 228.58 U/L, and achieved an oil accumulation of 49% of the cell dry weight while maintaining a stable protein content of 33% [6]. Industrial Application Potential - In a 5-liter fermentation scale-up, the laccase activity further increased to 240.43 U/L, with oil content rising to 51%, indicating strong stability and potential for industrial applications [6][7]. - The research highlights the effective conversion of lignin into valuable microbial oils and proteins, providing a feasible pathway for high-value utilization of lignin resources [7][9]. Future Directions - The research is supported by national strategic technology initiatives, and the team has filed for two patents related to their findings. They will present their latest research at the upcoming NFUCon 2025 forum, focusing on biomass utilization strategies [8][9].