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血液生物标志物与老年“多病共存”风险相关
Xin Lang Cai Jing· 2026-01-13 12:33
Core Insights - An international study involving the Karolinska Institute in Sweden has identified a set of common blood biomarkers that are closely related to the risk of "multimorbidity" and the accumulation of diseases in the elderly [1][2] - The research analyzed the health status of over 2,200 individuals aged 60 and above in Stockholm over a period of 15 years, revealing that 7 out of 54 biomarkers were associated with multimorbidity [1] - The findings suggest that future blood tests could help doctors identify at-risk populations for early health management and intervention [2] Group 1 - The study found that biomarkers such as growth differentiation factor 15, glycated hemoglobin, cystatin C, leptin, and insulin are related to the overall burden of chronic diseases and common disease combinations [1] - Gamma-glutamyl transferase and albumin were primarily associated with the speed of disease progression [1] - The research also validated its findings using health data from 522 individuals in the U.S., which yielded consistent results [1] Group 2 - The researchers emphasized that the findings reveal statistical correlations rather than direct causation of multimorbidity by specific biomarkers [1] - The study indicates that metabolic disorders, stress responses, and energy regulation abnormalities may be significant biological factors driving the occurrence and development of multimorbidity in the elderly [1] - Future research will track how these blood biomarkers change over time and whether lifestyle or medication can influence the related pathological processes [2]