抗微生物药物耐药(AMR)

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为何它已成全球健康领域的主要威胁?达沃斯论坛上的专家开出了“药方”
Di Yi Cai Jing· 2025-06-25 09:06
Core Insights - Emerging infectious diseases and antimicrobial resistance (AMR) are major global health threats closely linked to zoonotic diseases, requiring improved interdepartmental collaboration and the promotion of innovative solutions [1][2][3] Group 1: Challenges in Disease Control - The need for enhanced collaboration between health, agriculture, and environmental sectors is critical, as 75% of new infectious diseases are zoonotic, with climate change and human activities increasing cross-species transmission risks [3] - The rising antibiotic resistance among bacteria poses significant challenges, as many antimicrobial drugs are losing effectiveness, leading to prolonged treatment periods and potential treatment failures [3][4] - The implementation of the "One Health" concept is gaining consensus among academia, international organizations, and governments to address zoonotic diseases effectively [3][4] Group 2: Innovation and Technology - Advances in genomic sequencing technology for infectious disease monitoring have improved, but commercialization and large-scale application remain challenges [1][8] - Digital technologies, including AI, are seen as transformative for implementing the "One Health" strategy, enhancing monitoring of antibiotic resistance and clinical decision-making [8] - The lack of consensus on high-throughput sequencing technology in veterinary diagnostics highlights the need for cross-departmental integration to overcome monitoring challenges [6][8] Group 3: Funding and Resource Allocation - Sustainable funding is essential for promoting innovative solutions, particularly in low-resource settings, where health budgets are constrained [9] - The World Bank emphasizes the importance of collaborative financing models to support monitoring systems and the "One Health" strategy, involving private sector participation [9]