◎实习记者 王 晶 不同材质合金首饰的致敏性存在差异，这主要与金属的电化学特性和人体免疫反应机制有关。王晓艳 说："夏季炎热易出汗，金属和皮肤的接触更紧密，汗液增多会使金属离子析出。"此外，汗液里含有氯 离子等电解质，可以电解金属。合金首饰中的镍、铬、钴等部分金属，遇到电解质后会被加速电解成离 子形式。这些离子作为一种半抗原，会和皮肤表层的蛋白结合，进而产生过敏反应。 王晓艳说，刚佩戴合金首饰时，由于人体皮肤屏障完整，不容易引起过敏。但随着首饰与皮肤进行摩擦 以及汗液的影响，金属表面的离子释放会逐渐增多，就容易引发过敏反应，出现过敏症状。 随着金属过敏刺激不断加强，皮肤屏障被进一步破坏，不仅导致皮肤局部过敏，还可能使金属离子被皮 肤吸收，进入血液和器官。当人体内的金属离子蓄积到一定浓度，有可能会引发其他风险，甚至造成多 器官疾病。 王晓艳强调："首饰与皮肤的局部接触不意味一定会引起全身的严重反应。如果佩戴手链或者耳环等小 面积接触首饰，主要会对局部接触部位的皮肤造成危害。如果皮肤屏障完整，这些金属透皮吸收的概率 不超过2%，不必过于恐慌。" 当下，凭借"高颜值、低价格"，合金首饰成为网络消费新宠。然而，这类看 ...

Core Viewpoint - The article discusses the increase in patients presenting with "small blisters" on hands and feet during the summer, primarily caused by various skin conditions, with a focus on sweat eczema as the most common cause [1][2]. Group 1: Common Conditions - The most common condition leading to "small blisters" is sweat eczema, characterized by small blisters on the palms and soles, often accompanied by severe itching [2][3]. - Other potential causes include athlete's foot, hand-foot eczema, contact dermatitis, and hand-foot-mouth disease, each with distinct characteristics and treatment approaches [3][4]. Group 2: Symptoms and Diagnosis - Patients typically experience blisters on the sides of fingers, palms, and soles, with symptoms worsening at night or with heat, leading to potential secondary infections if scratched [2][3]. - Sweat eczema is noted for its self-limiting nature, often exacerbating in summer and improving in fall and winter, with recurrent episodes leading to skin thickening and cracking [2][3]. Group 3: Treatment Approaches - Treatment for sweat eczema focuses on symptomatic relief, with options like calamine lotion for itching and topical corticosteroids for severe cases [6]. - Athlete's foot requires maintaining dry skin and may involve antifungal medications, with an emphasis on completing the full treatment course to prevent recurrence [6]. - Hand-foot eczema treatment involves avoiding irritants and may include wet dressings during acute phases, transitioning to topical corticosteroids as the condition stabilizes [6]. - Contact dermatitis treatment emphasizes identifying and removing the irritant, followed by appropriate topical or oral medications as needed [6][7].