Core Insights - The recent launch of the drug micro-manufacturing system by Ruizhi Pharmaceutical in collaboration with East China Normal University marks a significant advancement in the field of antibody-drug conjugates (ADCs) and nucleotide phosphoramidite monomer synthesis [1][2] - This intelligent micro-flow technology addresses the bottleneck of "pilot scale-up" in drug development, transforming traditional production methods into continuous, smart, and precise "desktop" manufacturing [1] - The ADC micro-manufacturing system integrates multiple steps of the coupling reaction into a single chip, allowing for millisecond-level monitoring and precise control of key quality attributes, significantly reducing batch-to-batch variability [1] Summary by Sections Technology and Innovation - The newly released ADC micro-manufacturing system can shorten the process development and optimization time from weeks to days [1] - Key technical challenges such as chip manufacturing, stability, and multiphase fluid control have been overcome, achieving a 100% localization rate for core components and reducing overall costs by over 50% compared to imported solutions [1] Company Strategy and Market Position - The drug micro-manufacturing system enhances the company's one-stop, platform-based service capability, marking a significant step towards achieving certainty in ADC and small nucleic acid drug development [2] - The system is expected to reduce ADC drug process development time by 70% and lower the cost of nucleotide monomer synthesis by over 40% [2] - Ruizhi Pharmaceutical currently provides comprehensive new drug lifecycle services to global pharmaceutical companies, biotech firms, and research institutions, having established strategic partnerships with over 150 leading biopharmaceutical research organizations and enterprises [2] Educational Collaboration - East China Normal University's School of Pharmacy, established in May 2023, focuses on developing cutting-edge technologies such as artificial intelligence pharmacy, drug manufacturing, digital drugs, and nucleic acid and cell drugs [2] - The school aims to become a leading base for drug science and a training ground for future pharmaceutical talent, addressing both international frontiers and national strategic needs [2]