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解码植物干细胞的无限“复刻”:让珍稀药材实现“吨级”生产,技术革命破解千年药源困境|追寻新质生产力
Hua Xia Shi Bao· 2025-06-10 09:15
Core Viewpoint - The article highlights the breakthrough in plant stem cell technology, which allows for the efficient production of rare medicinal plants like ginseng, addressing the scarcity of high-quality traditional Chinese medicine resources [5][6][10]. Group 1: Technology and Innovation - Plant stem cells are crucial for the regeneration of plant organs and the synthesis of secondary metabolites, but their natural occurrence is extremely low [2]. - The technology enables the separation of stem cell lines from rare medicinal plants, such as the century-old wild ginseng, and allows for long-term preservation of genetic resources through low-temperature storage [2][5]. - The induced differentiation of stem cells can produce tons of ginseng adventitious roots in bioreactors, significantly increasing the yield and quality of active ingredients [5][9]. Group 2: Market Impact and Applications - The ginseng adventitious roots produced using this technology have a saponin content of 30,235 mg/kg, which is 14 times that of 15-year-old ginseng, showcasing the technology's potential for high-quality product development [5][9]. - The technology has been successfully applied to other rare medicinal plants, including Taxus chinensis and Tianshan snow lotus, expanding its market potential [6][11]. - The company aims to establish a global "rare plant stem cell bank" to share its resources and innovations with the world [6][14]. Group 3: Industry Standards and Future Prospects - The first technical regulations for ginseng adventitious root tissue culture in China were approved, providing a comprehensive guideline for enterprises and research institutions [13]. - The company has invested 5 billion yuan in a new plant stem cell industrial park, which is expected to become the largest plant stem cell production base globally [11][12]. - The annual output value of the ginseng stem cell series products is projected to exceed 10 billion yuan after full-scale production [12].
安然集团:打造珍稀药用植物干细胞“银行”
Zhong Guo Jing Ji Wang· 2025-05-30 12:07
Core Insights - Shandong Anran Group has successfully addressed the challenge of extracting, replicating, and scaling the production of effective components from rare medicinal plants, thereby conserving land resources and meeting the growing health demands of people [1] Group 1: Technology and Innovation - The company utilizes plant stem cell technology to extract stem cells from rare wild ginseng and has achieved a production upgrade from grams to tons through asexual reproduction via bioengineering [1] - Anran has developed a series of wild ginseng stem cell products, with the first phase of industrialization achieving an annual output value of nearly 2 billion yuan [1] - The stem cells, which are rare in plants, are the source of plant vitality and have been the focus of research since the 1950s in China, but industrialization has faced significant challenges until now [1][4] Group 2: Research and Development - In collaboration with Harbin Institute of Technology, Anran established the Harbin Institute of Technology-Anran Nano Life Health Science Research Center in 2014, marking the beginning of its foray into plant stem cell technology [2] - The company has introduced a rare wild ginseng specimen from Changbai Mountain, which has been certified as a top-grade ginseng by the National Ginseng and Deer Products Quality Supervision and Inspection Center [2] - Anran's research team has successfully induced, extracted, and separated stem cells from this top-grade wild ginseng, resulting in a product that is a precise genetic copy of the original ginseng [3] Group 3: Market Potential and Future Plans - The stem cell product derived from wild ginseng has shown remarkable results, containing significantly higher levels of rare ginsenosides compared to 15-year-old ginseng, indicating strong potential for anti-aging and anti-tumor effects [3] - Anran is building the world's largest plant stem cell industrial park to facilitate the large-scale production and commercialization of plant stem cell technology, with projected annual output value exceeding 10 billion yuan upon reaching full capacity [3] - The company has filed nearly 40 national invention patents and is leading the formulation of industry standards for ginseng tissue culture technology, promoting the standardized development of the plant stem cell industry [4]