横纹肌溶解综合征
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运动后大量饮水,美籍教授“水中毒”
Xin Lang Cai Jing· 2026-01-21 17:29
本报讯 近日,一名在琼工作的37岁美籍教授,因突发严重意识障碍、抽搐、多系统功能紊乱被紧急送 至海口市人民医院。经该院重症医学科、神经内科等多学科团队连续数日的精准救治与接力诊疗,患者 目前已脱离生命危险,神志清醒,病情平稳,在后续康复治疗后顺利出院。 去年12月29日,Maske教授在运动后大量饮水,出现剧烈头痛、乏力,随后在短时间内进展为意识丧 失、四肢强直、牙关紧闭,持续约1小时。被120送入医院时已处于浅昏迷状态,生命体征不稳。 海口市人民医院立即启动危重患者救治绿色通道,患者被迅速收入重症医学科进行高级生命支持。在重 症医学科团队数日治疗后,Maske教授意识逐渐恢复,抽搐得到控制,内环境趋于稳定,生命体征平 稳。经神经内科专家会诊评估,Maske教授符合转科标准,于新年第一天顺利转入神经内科进行后续的 神经系统专科治疗与康复。 转入神经内科后,重点围绕脑功能恢复与并发症预防展开康复。在持续进行脱水降颅压、营养神经等治 疗的同时,逐步介入肢体功能训练与认知康复。经过精心治疗与护理,Maske教授意识进一步清醒,定 向与记忆能力改善,肢体活动逐步恢复,近日顺利出院。记者 钟起的 急诊检查结果令人揪心: ...
警惕药物诱发横纹肌溶解综合征
Xin Lang Cai Jing· 2026-01-06 00:56
Core Viewpoint - Rhabdomyolysis is a serious muscle disease caused by various factors, with certain medications being significant triggers. Understanding the mechanisms of drug-induced rhabdomyolysis and adhering to proper medication guidelines can help prevent its occurrence [1]. Disease Symptoms - Rhabdomyolysis results from the necrosis of muscle cells, leading to the release of intracellular substances into the bloodstream. Symptoms include muscle pain, weakness, and dark-colored urine, which are indicative of muscle damage. Other systemic symptoms may include fever, tachycardia, confusion, nausea, and vomiting. Rapid deterioration can lead to acute kidney injury, disseminated intravascular coagulation, and multi-organ failure, posing a life-threatening risk [2]. Medication Alerts - Statins and fibrates are notable medications that can induce rhabdomyolysis. Statins, such as atorvastatin, pravastatin, and rosuvastatin, lower blood cholesterol and regulate lipids but can increase the risk of rhabdomyolysis, especially at higher doses or when combined with certain drugs like cyclosporine and erythromycin. Fibrates, including fenofibrate and bezafibrate, can also disrupt muscle cell energy metabolism, leading to similar risks. Other drug classes, such as antipsychotics, fluoroquinolone antibiotics, antidepressants, and sedatives, may also contribute to rhabdomyolysis [3]. Prevention Strategies - To prevent rhabdomyolysis, patients should avoid exceeding prescribed dosages of medications, be cautious of drug interactions, and refrain from consuming grapefruit juice while on statins. Regular health check-ups, including liver and kidney function tests, are recommended for patients on long-term medications that may induce rhabdomyolysis. Monitoring for any unusual symptoms is crucial for timely medical intervention [4][5].