（来源：科普中国） 转自：科普中国 很多人以为"免疫力越强越好，就越不容易生病"，但免疫学的研究告诉我们：免疫系统最重要的不是强，而是平衡。就像紧急制动和油门需要互相配合一 样，免疫反应必须在够用但不过度的区间内工作。偏向任何一端，都可能给身体带来麻烦。 然而，在生活中，我们经常在不自觉间做了一些事，让免疫系统从动态平衡滑向紊乱。下面我们就来讲讲几个容易削弱抵抗力的行为。 图库版权图片，转载使用可能引发版权纠纷 1.持续的负面情绪 让免疫系统误判战场 《临床神经科学对话》上一篇综述指出，情绪与免疫并不是两个分离的系统，而是共享同样的调节逻辑，会互相镜像变化[1]。 当一个人长期处在焦虑、愤怒或沮丧中时，大脑负责调节情绪的区域会影响免疫细胞的表达，使促炎基因上调、抗感染基因下调。这意味着免疫系统在情 绪混乱时更容易出现"反应过度"或"反应不足"的情况。 情绪系统的塑性与免疫细胞的塑性高度同步，长期负面情绪会让两个系统一同走向失衡[1]。这不是心理层面的抽象概念，而是真实地体现在血液里—— 比如 C 反应蛋白升高，或特定炎症因子表达增强。 2.心理失衡 会降低抗感染能力 会让免疫系统失去训练 免疫系统需要不断接收 ...

Core Concept - The article discusses the phenomenon of trypophobia, characterized by an intense fear and disgust towards clusters of holes or cracks, and explores its psychological origins and societal implications [2][17]. Group 1: Psychological Aspects - Trypophobia is described as a psychological condition that elicits feelings of fear and nausea when individuals encounter clusters of holes or cracks [2][4]. - There is ongoing debate among psychologists regarding whether trypophobia should be classified as a legitimate phobia, with some arguing it is merely a reaction of disgust rather than fear [2][3]. - The condition may be linked to evolutionary responses aimed at avoiding pathogens, as feelings of disgust are thought to protect humans from disease [4][5]. Group 2: Triggers and Symptoms - Common triggers for trypophobia include images of natural objects like lotus seed pods, as well as everyday items that exhibit similar patterns [2][3]. - Individuals with trypophobia often experience heightened reactions to images that resemble potential pathogens, even if those images are harmless [7][12]. - The symptoms can severely impact daily life, leading individuals to avoid certain environments or media that may contain triggering visuals [12][15]. Group 3: Social and Cultural Context - The rise of the internet has facilitated the spread of trypophobia-related content, creating communities where individuals share their experiences and coping mechanisms [3][11]. - Exposure therapy and ASMR (Autonomous Sensory Meridian Response) videos are discussed as potential methods for individuals seeking relief from their symptoms, although the effectiveness of these methods for trypophobia remains unverified [9][11]. - The phenomenon has led to a subculture that connects individuals through shared experiences of fear and disgust, highlighting the social aspect of the condition [18][19].