还在为液质联用实验难题熬夜查文献？三重四极杆定量结果重复性差、高分辨质谱没数据库不会定性、复杂样品基质效应难消除…… 这些让你头疼的 "卡点"，来 直播间听听专家解决思路！ 9 月 30 日 10:00-11:00，仪课通重磅推出《液质联用应用实战答疑——从方法到案例问题解析》直播课程，直播特邀拥有 30 年质谱行业经验的蒋宏键老师——他不 仅是中国第一台 API-LC/MS、CE/MS 的安装与培训负责人，更懂一线实验员的真实痛点！ 扫码提前预约 本次直播，能解决你哪些核心问题？ 1.三重四极杆低分辨质谱的靶向定量和定性的问题 特别提示 微信机制调整，点击顶部"仪器信息网" → 右上方"…" → 设为 ★ 星标，否则很可能无法看到我们的推送。 2.三重四极杆测定蛋白质大分子的体会及疑问 3.高分辨质谱不带数据库，如何进行定性？ 4.样品多次进样后，信号响应逐渐降低，甚至消失的原因排查 为什么一定要参加这场直播？ 1. 专家够权威，经验够 "落地"：专家解答真实实验问题，解决"卡点" 2.案例导入：结合用户检测案例，贴近真实工作场景 3.干货分享：三重四级杆低分辨质谱、高分辨质谱定性及定量问题 4.专享好礼： ...

Core Viewpoint - Beijing Shidilong Technology Co., Ltd. has announced the establishment of a new subsidiary focused on mass spectrometry technology, indicating a strategic move to enhance its capabilities in this field [1] Group 1 - The company will invest 10 million yuan in collaboration with Beijing Huairou Hard Technology Innovation Service Co., Ltd. to set up the subsidiary [1] - The newly established subsidiary is named Huizhong Mass Spectrometry (Beijing) Technology Co., Ltd. and has completed its business registration [1] - The legal representative of the subsidiary is Ge Yijie, and it was officially established on August 14, 2025 [1] Group 2 - The business scope of the subsidiary includes technical services and instrument sales, covering multiple areas [1]

Group 1 - The company held its 20th meeting of the 5th Board of Directors on August 4, 2025, with all 7 directors present, complying with legal and procedural requirements [1] - The board approved a proposal to invest 8 million RMB to establish a holding subsidiary focused on mass spectrometry technology, with a total registered capital of 10 million RMB [1] - The investment does not constitute a related party transaction or a major asset restructuring, and the decision was unanimously supported by all directors [2] Group 2 - The company plans to reduce its repurchased shares through centralized bidding, with a maximum of 6,357,609 shares, representing up to 1% of the total share capital [2] - The reduction period is set from August 27, 2025, to November 27, 2025, excluding any periods prohibited by regulatory authorities [2]

证券代码：002658 证券简称：雪迪龙 公告号：2025-030 北京雪迪龙科技股份有限公司 关于对外投资设立控股子公司的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚 假记载、误导性陈述或重大遗漏。 一、对外投资概述 北京雪迪龙科技股份有限公司（以下简称"公司"）拟与北京怀柔硬科技创 新服务有限公司（以下简称"怀柔硬科技公司"）共同出资设立控股子公司怀众 质谱（北京）技术有限公司（暂定名，以市场监督管理局核定为准，以下简称"控 股子公司"）。控股子公司将聚焦质谱技术领域，组织开展质谱共性技术、关键 核心部件的研发，组织开展质谱新技术验证、评价及应用推广，促进质谱行业交 流合作，推动行业发展。 控股子公司注册资本为1,000万元，其中公司以自有资金出资800万元，占控 股子公司注册资本的80.00%，怀柔硬科技公司出资200万元，占控股子公司注册 资本的20.00%。 次会议，审议通过了《关于对外投资设立控股子公司的议案》，同意公司以自有 资金出资人民币800万元与北京怀柔硬科技创新服务有限公司共同出资设立控股 子公司，其注册资本为人民币1,000万元，控股子公司将聚焦质谱技术领域， ...

控股子公司注册资本为1000万元，其中公司以自有资金出资800万元，占控股子公司注册资本的80%。 智通财经APP讯，雪迪龙(002658.SZ)公告，公司拟与北京怀柔硬科技创新服务有限公司(简称"怀柔硬科 技公司")共同出资设立控股子公司怀众质谱(北京)技术有限公司(暂定名)。控股子公司将聚焦质谱技术 领域，组织开展质谱共性技术、关键核心部件的研发，组织开展质谱新技术验证、评价及应用推广，促 进质谱行业交流合作，推动行业发展。 ...

Group 1 - The company plans to establish a joint venture named Huazhong Mass Spectrometry (Beijing) Technology Co., Ltd. with Beijing Huairou Hard Technology Innovation Service Co., Ltd. [1] - The registered capital of the joint venture is 10 million yuan, with the company contributing 8 million yuan, accounting for 80% of the capital, while Huairou Hard Technology contributes 2 million yuan, accounting for 20% [1] - The investment aims to focus on the mass spectrometry technology field, promoting industry communication and cooperation, and facilitating industry development [1] Group 2 - The investment amount represents 0.31% of the company's most recent audited net assets and will not have a significant adverse impact on the company's financial and operational status [1]

Core Viewpoint - Thermo Fisher Scientific launched two innovative mass spectrometers, Orbitrap Astral Zoom and Orbitrap Excedion Pro, at ASMS 2025, aimed at advancing research in complex biological processes and major diseases such as Alzheimer's and cancer, thereby enhancing precision medicine and biopharmaceutical development [1][2]. Group 1: Orbitrap Astral Zoom Highlights - The Orbitrap Astral Zoom features a 35% increase in scanning speed, facilitating rapid data collection [4]. - It offers a 40% improvement in throughput, supporting large-scale sample screening [4]. - The system enhances multi-detection capabilities by 50%, enabling multidimensional analysis in a single experiment [4]. - Applications include deep proteomics analysis and trace biomarker discovery [4]. Group 2: Orbitrap Excedion Pro Highlights - The Orbitrap Excedion Pro integrates next-generation Orbitrap technology with complementary fragmentation techniques, providing breakthrough solutions for analyzing complex biomolecules [7]. - It accelerates biopharmaceutical development by enabling in-depth analysis of monoclonal antibodies and other biological therapeutics [7]. - Enhanced sensitivity, dynamic range, and reliability allow for simultaneous high-quality data on proteins and post-translational modifications [9]. - The system supports research in cardiovascular diseases, neuroscience, and oncology [7]. Group 3: Overall Impact and Ecosystem - Both instruments strengthen Thermo Fisher's "end-to-end" research ecosystem, which includes reagents, imaging systems, and advanced mass spectrometry workflows [7]. - They provide robust support for proteomics, biopharmaceutical characterization, and translational medicine, focusing on disease mechanism research and target validation [7].

Core Points - The American Society for Mass Spectrometry (ASMS) announced the winners of its 2025 awards, including the John B. Fenn Award for Outstanding Contribution, the Biemann Medal, and the Al Yergey Mass Spectrometry Scientist Award [1][2]. Group 1: John B. Fenn Award for Outstanding Contribution - Jack Henion, a professor emeritus at Cornell University and co-founder of Advion, received the 2025 John B. Fenn Award for Outstanding Contribution for his pioneering research in liquid chromatography-mass spectrometry (LC-MS) and atmospheric pressure ionization [4][8]. - Henion has published over 235 peer-reviewed papers and holds 12 patents related to his work, significantly advancing mass spectrometry applications in biomedical research [4]. Group 2: Biemann Medal - Dr. Livia Schiavonato Eberlin from Baylor College of Medicine was awarded the 2025 Biemann Medal for her innovative research that has advanced mass spectrometry in biomedical studies [6][9]. - Eberlin has published over 95 scientific papers and received numerous honors, including the MacArthur Fellowship, with her work supported by various prestigious institutions [6]. Group 3: Al Yergey Mass Spectrometry Scientist Award - The 2025 Al Yergey Mass Spectrometry Scientist Award recipients include Vilmos Kertesz, Michael Shortreed, and John E.P. Syka, recognized for their significant contributions to the development and application of mass spectrometry technology [15]. Group 4: Research Awards - The 2025 Research Award winners are Tian (Autumn) Qiu, Qing Yu, and Varun Gadkari, who are recognized for their contributions to scientific research in the early stages of their academic careers [19]. Group 5: PUI Award and Ron Hites Award - Emma Guiberson from Middlebury College received the PUI Award, which supports mass spectrometry research in primarily undergraduate institutions, with a funding of $20,000 [23]. - Christian Bleiholder from Florida State University was awarded the Ron Hites Award for his outstanding paper published in the Journal of the American Society for Mass Spectrometry (JASMS) [23]. Group 6: Postdoctoral Career Development Award - The 2025 Postdoctoral Career Development Award winners include Jamie P. Butalewicz, Brianna Garcia, Kathryn Kapp, Jericha Mill, and Carlis mari Oliveira Grundmann, recognized for their contributions to mass spectrometry research [30].

Core Insights - The article discusses the recent breakthroughs in the mass spectrometry field and the future evolution of technology, emphasizing the role of Chinese companies in global competition [1] Group 1: Recent Developments in Mass Spectrometry - The 2025 China Scientific Instrument Development Annual Conference (ACCSI 2025) highlighted mass spectrometry as a core topic, showcasing its significance in the scientific instrument industry [1] - The conference featured three main forums: the Mass Spectrometry Industrialization Forum, the Talent Development Forum, and a discussion on domestic alternatives, forming a complete loop of "technology leadership—talent support—industry breakthrough" [1] Group 2: Future Breakthroughs in Mass Spectrometry - Experts identified key future breakthroughs in mass spectrometry, including high throughput, high resolution, portability, and intelligence [3] - The emergence of open ion sources in 2004 marked a rapid innovation period for mass spectrometry, leading to new applications such as high-throughput and in-situ analysis [3] Group 3: Technological Innovations and Applications - CDMS technology addresses challenges in analyzing heterogeneous biological macromolecules, positioning itself as a vital tool for next-generation biological analysis [4] - Mass spectrometry imaging technology is evolving towards higher spatial resolution and multi-dimensional data acquisition, enhancing its application in various fields [4][11] Group 4: Domestic Market Dynamics - The Chinese scientific instrument market has experienced rapid expansion, becoming a core driver of global market growth, with international brands accelerating localization efforts [18] - Companies like Shimadzu have made significant strides in localizing mass spectrometry products, achieving full domestic production of high-end systems by April 2025 [18] Group 5: Domestic Innovation and Collaboration - Domestic mass spectrometry companies are transitioning from following to innovating, with significant advancements in high-resolution mass spectrometry technology [19] - Collaborative innovation models involving academic institutions and enterprises are proving effective in bridging the gap between basic research and industrial application [20] Group 6: Talent Development and Industry Growth - The Mass Spectrometry Talent Development Forum emphasized the importance of cultivating talent to support the autonomous breakthroughs in the mass spectrometry industry [27] - The forum aimed to create a closed loop of "education-research-industry" to propel China's mass spectrometry industry from a follower to a leader [27] Group 7: Domestic Alternatives and Strategic Discussions - A discussion on "Domestic Alternatives New Era" highlighted the urgency of achieving self-sufficiency in core scientific instruments amid increasing international trade tensions [28] - Experts agreed on the necessity of accelerating the development of core instruments to ensure national technological security [28]