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上海交大冯雁教授:酶分子工程加速生物产业发展 | SynBioCon 2025大会
Core Viewpoint - The article emphasizes the significance of high-value compounds, such as amino acids and pharmaceutical intermediates, in the field of biomanufacturing, highlighting China's role as a major producer supporting global industry development [1]. Group 1: Biomanufacturing and Synthetic Biology - High-value compounds are crucial in biomanufacturing, with China being a leading producer in this sector [1]. - A major bottleneck in synthetic biology is the insufficient availability of biological components, which can be addressed through breakthroughs in enzyme design and gene editing technologies [1]. - The research team led by Professor Feng Yan from Shanghai Jiao Tong University focuses on developing efficient biocatalysts and new synthetic pathways for artificial compounds, surpassing natural evolution [1][3]. Group 2: Research Innovations - The research team utilizes second-generation sequencing for functional analysis of large mutation libraries, enabling rapid identification of important protein scenarios [1]. - The team has developed methods to create new proteins with over 50% sequence variation, which can be applied in the production of industrial enzymes [1]. Group 3: Upcoming Conference - The SynBioCon 2025 conference will be held from August 20-22 in Ningbo, focusing on AI and biomanufacturing, as well as opportunities in green chemistry, new materials, future food, and agriculture [6]. - The conference will feature various activities, including a macro forum on biomanufacturing, youth forums, and discussions on the 2025 Blue Book for AI-enabled biomanufacturing innovation [6][7].