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上海交大冯雁教授:酶分子工程加速生物产业发展 | SynBioCon 2025大会
合成生物学与绿色生物制造· 2025-07-28 12:59
Core Viewpoint - The article emphasizes the significance of high-value compounds, such as amino acids and pharmaceutical intermediates, in the field of biomanufacturing, highlighting China's role as a major producer supporting global industry development [1]. Group 1: Biomanufacturing and Synthetic Biology - High-value compounds are crucial in biomanufacturing, with China being a leading producer in this sector [1]. - A major bottleneck in synthetic biology is the insufficient availability of biological components, which can be addressed through breakthroughs in enzyme design and gene editing technologies [1]. - The research team led by Professor Feng Yan from Shanghai Jiao Tong University focuses on developing efficient biocatalysts and new synthetic pathways for artificial compounds, surpassing natural evolution [1][3]. Group 2: Research Innovations - The research team utilizes second-generation sequencing for functional analysis of large mutation libraries, enabling rapid identification of important protein scenarios [1]. - The team has developed methods to create new proteins with over 50% sequence variation, which can be applied in the production of industrial enzymes [1]. Group 3: Upcoming Conference - The SynBioCon 2025 conference will be held from August 20-22 in Ningbo, focusing on AI and biomanufacturing, as well as opportunities in green chemistry, new materials, future food, and agriculture [6]. - The conference will feature various activities, including a macro forum on biomanufacturing, youth forums, and discussions on the 2025 Blue Book for AI-enabled biomanufacturing innovation [6][7].
第一波嘉宾剧透!第四届合成生物与绿色生物制造大会(8月20-22日 宁波)
DT新材料· 2025-07-23 16:01
Core Viewpoint - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on the integration of AI with bio-manufacturing, green chemicals and new materials, future food, and future agriculture [1]. Group 1: Conference Overview - The conference aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan, innovations driven by AI in bio-manufacturing, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [1]. - The event will facilitate the transfer and transformation of scientific achievements, product scaling, and talent acquisition [1]. Group 2: Organizers and Support Units - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by several institutions including Peking University Ningbo Institute of Ocean Medicine and Ningbo Enzyme Science Bioengineering Co., Ltd. [2]. - Supporting units include the Chinese Society of Biotechnology's Bio-based Materials Committee, Zhejiang Synthetic Biology Industry Technology Alliance, and Shanghai Future Industry Bio-Manufacturing Committee [2]. Group 3: Expert Speakers - Notable speakers include Zhang Xian'en, Dean of the Synthetic Biology Institute at Shenzhen University, who is recognized for his contributions to synthetic biology and bio-manufacturing [6][7]. - Other experts include professors from various universities who will share insights on topics such as the construction of efficient cell factories for aromatic compound production and the biomanufacturing of polyamide materials [10][15][28]. Group 4: Conference Agenda - The agenda includes a series of forums and discussions on topics such as green chemicals and new materials, AI in bio-manufacturing, and future food and agriculture [41]. - The first day features a macro forum on the bio-manufacturing industry, while subsequent days will include specialized forums and networking opportunities [41]. Group 5: Registration and Participation - Registration for the conference is open, and participants can sign up to engage in discussions and networking opportunities related to synthetic biology and bio-manufacturing [42][44].
第一波嘉宾剧透!第四届合成生物与绿色生物制造大会(8月20-22日,宁波)
合成生物学与绿色生物制造· 2025-07-23 13:47
Core Viewpoint - The SynBioCon 2025 conference will focus on the integration of AI with biomanufacturing, green chemicals and new materials, future food, and future agriculture, aiming to explore the development trends of the biomanufacturing industry during the 14th Five-Year Plan period [1]. Group 1: Conference Overview - The conference will take place from August 20-22, 2025, in Ningbo, Zhejiang [1]. - It aims to promote the transfer and transformation of scientific and technological achievements, product scaling, and talent acquisition in the biomanufacturing sector [1]. Group 2: Organizers and Support Units - Organized by Ningbo Detaizhongyan Information Technology Co., Ltd. (DT New Materials) and co-organized by several academic and research institutions [2]. - Supported by various associations and alliances, including the Chinese Society of Biotechnology and the Zhejiang Synthetic Biology Industry Technology Alliance [2]. Group 3: Expert Guests - Notable experts include Zhang Xian'en, Dean of the School of Synthetic Biology at Shenzhen University of Technology, and other prominent figures from various universities and research institutes [4][5][6][7][10][12][14][18][20][22][30][32]. - These experts will share insights on topics such as the construction of efficient cell factories and the development of biobased materials [8][11][23][27][31]. Group 4: Conference Agenda - The agenda includes a series of forums and discussions on topics like green chemicals, AI in biomanufacturing, and future food and agriculture [36][37]. - Activities will feature high-level discussions, youth forums, and technology showcases [36][37].
第一波嘉宾剧透!第四届合成生物与绿色生物制造大会(8月20-22日 宁波)
DT新材料· 2025-07-22 16:03
Core Viewpoint - The fourth Synthetic Biology and Green Bio-Manufacturing Conference (SynBioCon 2025) will be held from August 20-22 in Ningbo, Zhejiang, focusing on five key areas: AI + Bio-Manufacturing, Green Chemistry and New Materials, Future Food, and Future Agriculture. The conference aims to explore the development trends of the bio-manufacturing industry during the 14th Five-Year Plan, innovations driven by AI, and the technologies and products that will sustain the vitality of the bio-manufacturing sector [1]. Organizers and Support Units - The conference is organized by Ningbo Detaizhong Research Information Technology Co., Ltd. (DT New Materials) and co-organized by institutions such as Peking University Ningbo Institute of Ocean Medicine and Ningbo Enzyme Science Bioengineering Co., Ltd. It is supported by various associations and alliances in the field of synthetic biology [2]. Expert Guests - Notable experts, including Zhang Xian'en, Dean of the School of Synthetic Biology at Shenzhen University of Technology, will serve as advisory experts for the conference. Zhang has significant credentials, including being a Fellow of the American Institute for Medical and Biological Engineering and the Royal Society of Chemistry [6][7][8]. Conference Agenda - The agenda includes a series of forums and discussions on topics such as green chemistry, AI in bio-manufacturing, and future food and agriculture. The first day features a macro forum on the bio-manufacturing industry, while subsequent days will host specialized forums and networking events [41]. Key Topics of Discussion - The conference will cover various innovative topics, including the construction of efficient cell factories for producing aromatic compounds, the biomanufacturing of polyamide materials, and advancements in enzyme engineering for low-carbon bio-manufacturing [13][15][32][34]. Networking and Collaboration - The event aims to facilitate technology transfer, product scaling, and talent acquisition within the bio-manufacturing industry, promoting collaboration among enterprises, research institutions, and government bodies [1]. Registration and Participation - Interested participants can register for the conference, which promises to be a significant event for stakeholders in the synthetic biology and bio-manufacturing sectors [42][44].
蔚蓝生物(603739):技术创新驱动增长 国际化布局持续推进
Xin Lang Cai Jing· 2025-04-30 10:39
Core Insights - In 2024, the company achieved operating revenue of 1.32 billion yuan, a year-on-year increase of 10.16%, while net profit attributable to shareholders was 63 million yuan, a decline of 22.39% [1] - The decline in profit is attributed to increased depreciation expenses after the completion of the animal health industrial park, a 17.49% rise in management expenses, and a 46.48% increase in financial expenses due to interest expenses being recognized as costs [1] Enzyme Business - The enzyme business generated revenue of 505 million yuan in 2024, a year-on-year growth of 14.34%, becoming the main driver of the company's revenue growth [2] - The gross profit margin reached 63.69%, an increase of 2.89 percentage points, driven by continuous investment in technological innovation and optimization of production processes [2] - The company is expanding into various fields including industrial enzymes, food enzymes, and pharmaceutical enzymes, and has established an AI technology development laboratory to enhance R&D efficiency [2] Animal Health Products - Revenue from the animal health products business was 308 million yuan in 2024, a slight increase of 3.56%, but the gross profit margin fell to 33.51%, down 8.23 percentage points [3] - The decline in gross profit margin is primarily due to increased depreciation after the industrial park's completion, but long-term benefits are expected from improved product structure and quality [3] - The company plans to focus on biological products, particularly pig vaccines and imported generics, while also expanding into the pet medicine sector [3] Capacity and R&D Investment - With the increase in new capacity utilization and the gradual release of new products, the profitability of the animal health business is expected to recover [4] - The company invested 118 million yuan in R&D in 2024, a year-on-year increase of 6.81%, accounting for 8.95% of revenue, with 266 R&D personnel [4] - The company has established six technology centers and two key laboratories, with major projects expected to be operational by 2025, laying a foundation for future growth [4] Profit Forecast and Investment Recommendation - The expected EPS for 2025-2027 is projected to be 0.44 yuan, 0.51 yuan, and 0.60 yuan, corresponding to dynamic PE ratios of 29, 24, and 21 times, respectively, maintaining a "hold" rating [4]