[music] Have a look at these pictures. I tried to reproduce famous drawings of humans and rabbits embryos uh drawn by heckle. Can you tell for sure which one is human and which one is rabbit.Probably no. I wouldn't if it was not me who drew the pictures. Why they so similar.And how can such different organisms like humans and rabbits developed from a nearly identical embryo. Think of it. These are limps.Humans and horses. They are different for sure and they serve different purposes. Human arms are good for ...

Core Argument - The prevailing aging models inadequately address the role of persistent pathogens (viruses, bacteria, parasites) as a significant driver of human aging and healthspan reduction [1] - Persistent pathogens can embed themselves in tissues and nerves, potentially driving various health problems later in life [2][3][4] - These pathogens can actively distort the signaling of human genes, impacting multiple hallmarks of aging [8] Pathogen Prevalence and Impact - Approximately 95% of individuals harbor one or more strains of herpes virus [5] - Around 11% of people in the US and up to 87% in some global regions carry the chronic parasite toxoplasma [6] - Persistent SARS-CoV-2 virus has been found in tissue samples months or years after initial infection [7] - Pathogens can drive mitochondrial dysfunction by hijacking host cell metabolism [10][11][12] - Viruses can integrate into telomeres, leading to shorter and more unstable telomeres [13][14] - Viral proteins can interact with and distort the signaling of human aging pathways [15] Proposed Solutions and Recommendations - The industry needs to seriously consider the impact of persistent pathogens when developing healthspan extending interventions [17] - Curbing the activity of pathogens should precede interventions like gene editing [18] - Integrating existing antiviral and anti-parasite medications into healthspan protocols is recommended [18] - Individuals with herpes simplex virus who regularly took anti-herpes virus medications had a 10 times lower risk of developing dementia [19] - Investment in new diagnostic test platforms to identify persistent pathogens is crucial [20][21] - Incorporating the activity of persistent pathogens into aging models is essential for successfully extending healthspan [22]

Health Risk Alert - Four deaths have occurred due to a rare flesh-eating bacteria found in warm coastal waters [1] - At least 11 individuals have contracted illness from vibrio vulnificus [1] - Infections from vibrio vulnificus can be severe and life-threatening for some individuals [1] Bacteria & Infection Details - Vibrio vulnificus spreads through raw seafood, mainly oysters, or open wounds in direct contact with seawater [1] - The infection can spread rapidly [2] Prevention Measures - Doctors recommend covering open wounds with bandages if exposed to seawater [2] - Thorough cleaning of cuts and scratches is advised after seawater exposure [2]

Industry Trend - Awareness of the microbiome has grown, leading to increased availability of products designed to boost good bacteria in health-food shops [1] Product Analysis - The report questions the effectiveness of products claiming to boost good bacteria [1]

Beach Closures & Public Health Concerns - At least five states, including New York, California, Massachusetts, Michigan, Illinois, and Washington State, are tracking beach closures due to rising bacteria levels in the water [1] - Health officials are urging people not to enter the water at 17 beaches in the Chicago area [1] Bacteria & Infection Risks - There isn't one common cause across all regions; Washington State is dealing with toxic algae, while other areas are concerned about E coli [2] - Vibrio, a bacteria naturally occurring in coastal waters, is a concern due to potential spikes during extreme heat and heavy rain [2] - Infection can occur if swimmers swallow contaminated water or if water enters open wounds [2]