I'm going to talk about menopause and I'm going to talk about it in the sense of we already know so much about it or whatever we've heard but a lot of what we haven't heard about it is resilience and so I want to focus on how the brain and our emotions are fashioned by estrogen and we know that menopause is the start of the decline of estrogen but what happens when that hormone that has protected us for decades has started to fade. And what happens when estrogen, the quiet architect of balance in our bodies ...

Questions around the use of female hormone replacement therapy for years have kept women on the fence about these treatments. But in a new Wall Street Journal opinion piece, FDA Commissioner Dr. . Marty McCary says that it is time for drug manufacturers to remove blackbox warnings from these products because they've inappropriately scared women off.FDA Commissioner Dr. . Marty McCary joins us this morning to go more in depth on this. And Commissioner, thank you for being here today.Um, this is a a really bi ...

FDA & HRT Treatment Overview - FDA is clarifying the use of hormone replacement therapy (HRT) for perimenopause and menopause, suggesting previous risk assessments may be overstated [1] - The central argument revolves around whether the benefits of HRT outweigh the risks, particularly concerning stroke, blood clots, dementia, and breast cancer [3][6][8] Risk Assessment & Black Box Warning - Current medication labels include a black box warning about increased risks of heart disease, heart attack, strokes, and breast cancer [2][5] - The FDA is considering removing the black box warning due to arguments that the benefits of HRT outweigh the risks [5][6] - A 2002 women's health initiative study, with an average participant age of 63, is being re-evaluated, as HRT is often prescribed to women in their late 40s and 50s [6] - The perceived risk of breast cancer from HRT is considered by some to be overblown [7] - Baseline risk of developing breast cancer is around 13% for women in the United States [3][4] Benefits of HRT - Potential benefits of HRT include reduced risk of dementia and Alzheimer's, prevention of bone loss, and alleviation of menopause symptoms like hot flashes, poor sleep, and brain fog [8] - Estrogen, a key component of HRT, aids neurotransmitter function, potentially lowering the likelihood of dementia and Alzheimer's [9][10]

So, uh, first I'm going to talk about why men's hormonal health is in crisis. And I'm going to frame it in a way where we're really talking about health. Um, I'm going to specifically talk about testosterone, but not testosterone from a like I I want to be big and strong.Testosterone from the perspective of living a long and healthy life and, uh, avoiding chronic disease. So, uh, two really important points. The two greatest drivers of long life seen in published peer-reviewed research are high levels of st ...