Cardinal Health FY Conference Summary Company Overview - **Company**: Cardinal Health (NYSE: CAH) - **Date of Conference**: December 02, 2025 - **Key Speakers**: Aaron Alt (CFO), Matt Sims (VP of IR) Key Points Financial Performance - **Strong Q1 Results**: Cardinal Health reported double-digit growth across all five operating segments, driven by strong demand and execution [4][5] - **Revenue Growth**: The specialty part of the pharma business performed well, contributing to overall revenue growth [4][5] - **New Customer Volume**: Approximately $7 billion of new customer volume was added in the pharma business during the first half of the fiscal year [5][14] - **Full Year Guidance Raised**: The company raised its full-year guidance to $9.65-$9.85 [6] Business Segments - **Pharma Business**: The upcoming generic product pipeline from 2025 to 2029 is stronger than the previous five years, with generics being a significant revenue driver [8][9] - **At-Home and Nuclear Precision Health**: Both segments are experiencing double-digit organic growth, supported by investments in supply chain efficiency and capacity [22][23] - **OptiFreight**: This logistics technology provider is also seeing growth through better capabilities and customer penetration [23] Strategic Partnerships and Acquisitions - **Partnership with CVS**: The ongoing strategic partnership with CVS has been beneficial, especially after CVS's acquisition of Rite Aid, which brought new volume [12] - **Recent Acquisitions**: The integration of ADSG into the at-home business is progressing well, enhancing patient acquisition and care [6][24] Market Dynamics - **Competitive Landscape**: The medical products distribution market is undergoing changes with competitors exploring strategic alternatives, but Cardinal Health remains focused on its execution plan [27][28] - **Tariff Impact**: The company expects the net tariff impact to be at the top end of the previously disclosed range, but is managing pricing initiatives effectively [31] Regulatory Environment - **CMS Policies**: The administration's objectives for access, affordability, and innovation are aligned with Cardinal Health's goals, and the company is actively participating in policy discussions [33] - **Drug Price Negotiations**: The company has already factored potential impacts from drug price negotiations into its guidance [35] Future Outlook - **Investment in AI**: Cardinal Health is exploring AI opportunities across customer service, finance, and operations to enhance efficiency and effectiveness [48] - **DTC Models**: The rise of direct-to-consumer models is not seen as a threat, as many are supported by existing distributors [49] - **Long-term Growth Strategy**: The management is focused on long-term investments to ensure continued revenue and profit growth over the coming quarters [56][57] Capital Allocation - **Cash Flow Management**: The company raised its adjusted free cash flow guidance and plans to invest $600-$650 million in capital projects this fiscal year [44][46] - **Share Repurchase Program**: Cardinal Health is committed to a baseline share repurchase of at least $750 million [46] Innovation and Product Development - **GLP-1 Market**: The company anticipates that the introduction of oral solids will positively impact the GLP-1 market, potentially improving profitability [51] - **DME Regulatory Changes**: Cardinal Health believes it is well-positioned to thrive under new regulations due to its scale in the diabetes category [54] Conclusion - Cardinal Health is experiencing strong growth across its segments, driven by strategic partnerships, acquisitions, and a focus on innovation. The company is well-prepared to navigate market changes and regulatory challenges while maintaining a long-term growth strategy.

Financial Data and Key Metrics Changes - The company reported a strong fiscal year 2025, with EPS and adjusted operating income both up 16% [4] - The stock price has compounded at 25% over the years, with a 55% increase recently [4] - For fiscal 2026, the company expects operating income growth of 8%-10% on a consolidated basis, with U.S. healthcare operating income growth projected at 9%-11% [5][6] - Long-term operating income guidance has been raised to 6%-9% growth, with EPS growth expectations adjusted to 9%-13% [4][7] Business Line Data and Key Metrics Changes - The company has seen strong pharmaceutical utilization trends and sales of specialty products, contributing to outsized growth [7][8] - The oncology market has been impacted by a competitor acquisition, which is expected to create a 1% headwind, but excluding this, U.S. operating income growth could reach 10%-12% [6][8] Market Data and Key Metrics Changes - The international healthcare solutions segment faced challenges, with 85% of operating income coming from the U.S. and only 15% from international operations [50] - The core distribution business internationally performed well, particularly in the 3PL market, which is the fastest-growing part of the distribution business [51] Company Strategy and Development Direction - The company is focusing on expanding its specialty business and MSO (Managed Service Organization) capabilities, particularly in oncology and retina [8][15] - The strategy includes providing additional management services to physician practices, enhancing operational efficiency [15] - The company aims to maintain a pharmaceutical-centric approach in all strategic moves [15] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in long-term growth driven by pharmaceutical innovation and demographic trends [9] - There are concerns about potential policy-induced headwinds affecting coverage and insurance enrollment, but management believes pharmaceuticals will remain a critical and efficient form of care [11][12] - The company anticipates continued benefits from biosimilars and generic launches, which are expected to enhance operating income growth [28][30] Other Important Information - The company is committed to balanced capital deployment, with plans for $900 million in capital expenditures, strategic acquisitions, share repurchases, and a 9% increase in dividends [63][64] - The company is evaluating strategic alternatives for underperforming segments, including PharmaLex, while focusing on growth-oriented investments [56][61] Q&A Session Summary Question: What are the key growth drivers for the MSO business? - The MSO business is evolving through organic growth and acquisitions, with a focus on providing higher value services to physician practices [15][17] Question: How does the company view potential headwinds from drug pricing? - The company has historically advocated for community providers and aims to avoid unintended consequences from policy changes that could disrupt access to pharmaceuticals [24][25] Question: What is the impact of biosimilars on the company's revenue and profitability? - Biosimilars are expected to be a tailwind for distribution and GPO, with higher margins compared to brand products [27][28] Question: How is the company addressing challenges in the international market? - The company is focusing on its core distribution business, which has shown strength, while also addressing underperforming segments [50][51] Question: What is the company's approach to capital deployment? - The company prioritizes investments in infrastructure, strategic acquisitions, share repurchases, and dividend growth, maintaining a balanced approach to capital deployment [62][63]

Financial Data and Key Metrics Changes - The company reported a strong fiscal year 2025, with EPS and adjusted operating income both up 16% [4] - The stock price has compounded at 25% over the past several years, with a 55% increase recently [4] - Long-term operating income guidance has been raised to 6%-9% growth, with U.S. healthcare operating income growth expected at 9%-11% for 2026 [4][5] Business Line Data and Key Metrics Changes - The U.S. operating income growth is projected at 9%-11%, with a potential 10%-12% growth when excluding a 1% headwind from a competitor acquisition [5][6] - The specialty business continues to drive outsized growth, particularly in pharmaceutical utilization trends and sales of specialty products [7][8] Market Data and Key Metrics Changes - The international healthcare solutions segment saw weaker performance, with 85% of operating income coming from the U.S. and only 15% from international [50] - The 3PL market is identified as the fastest-growing part of the international distribution business, with improvements noted in the global specialty logistics business [51][53] Company Strategy and Development Direction - The company is focusing on expanding its MSO business, particularly in oncology and retina, to provide higher value services to physician practices [15] - A commitment to remain pharmaceutical-centric in all strategic moves, leveraging innovation in the pharmaceutical market and demographic trends for long-term growth [9][15] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in long-term growth driven by pharmaceutical innovation and demographics, despite expecting normalization in growth rates post-fiscal 2026 [9][10] - The company is optimistic about the international business for fiscal year 2026, with a turnaround in the global specialty logistics business noted [51][53] Other Important Information - The company plans to invest approximately $900 million in capital expenditures for infrastructure and technology in the current year [62] - A balanced capital deployment strategy includes strategic acquisitions, opportunistic share repurchases, and a commitment to increasing dividends [63][64] Q&A Session Summary Question: What are the key growth drivers for the MSO business? - The MSO business is evolving through organic growth and acquisitions, with a focus on providing management services to physician practices [15][17] Question: How does the company view potential headwinds from drug pricing? - The company has historically advocated for community providers and believes that pharmaceuticals are the most efficient form of care, which should mitigate potential pricing headwinds [24][25] Question: What is the impact of biosimilars on the business? - Biosimilars are expected to benefit the company from a distribution and GPO standpoint, as they offer higher margins compared to brand-name drugs [27][28] Question: How is the relationship with Walgreens affected by its privatization? - The relationship remains strong, with contracts in place until 2029, and the company continues to work on improving operational efficiencies [42][43] Question: What actions are being taken regarding the PharmaLex business? - The company is focusing on the more attractive parts of PharmaLex, particularly in pharmacovigilance, market access, and regulatory affairs, while evaluating strategic alternatives for less competitive segments [56][57]

Financial Data and Key Metrics Changes - The company reported a strong fiscal year 2025, with EPS and adjusted operating income both up 16% [5] - The stock price increased by approximately 55% over the year [5] - Long-term operating income guidance was raised to 6%-9% growth, with a 2026 forecast for U.S. healthcare operating income growth of 9%-11% [6][7] Business Line Data and Key Metrics Changes - The U.S. operating income growth is expected to be 9%-11%, with a potential 10%-12% growth when excluding a 1% headwind from a competitor acquisition [7][8] - The company is focusing on expanding its specialty business, particularly in oncology and retina markets, which are seen as key growth drivers [8][15] Market Data and Key Metrics Changes - The international healthcare solutions segment faced challenges, contributing only 15% to overall operating income, while the U.S. segment accounted for 85% [49] - The 3PL market is identified as the fastest-growing part of the international distribution business, with improvements noted in the global specialty logistics business [50][52] Company Strategy and Development Direction - The company is committed to a pharmaceutical-centric approach, focusing on specialty products and management services for physician practices [8][15] - Strategic acquisitions, particularly in the MSO space, are a priority, with plans to acquire the remaining 65% of OneOncology [17][63] - The company is also investing in infrastructure and technology, with capital expenditures projected at about $900 million [62][63] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in long-term growth driven by pharmaceutical innovation and demographic trends [9] - There are concerns about potential policy-induced headwinds affecting coverage and insurance enrollment, but management believes pharmaceuticals remain a critical and efficient form of care [10][12] Other Important Information - The company is evaluating strategic alternatives for underperforming segments, including parts of PharmaLex, while retaining growth-oriented businesses [56][60] - The dividend growth rate was increased to 9%, aligning with long-term EPS growth guidance of 9%-13% [63] Q&A Session Summary Question: What are the key growth drivers for the MSO business? - The MSO business is seen as a natural evolution of the specialty business, providing additional management services to physician practices [14][15] Question: How does the company differentiate itself from competitors in the MSO space? - The company maintains a pharmaceutical-centric focus, which is a key differentiator in its strategy [15] Question: What impact do potential drug pricing changes have on the business? - Management emphasized the importance of community-based providers and the efficiency of pharmaceuticals in maintaining care access [25][26] Question: How is the company addressing challenges in the international market? - The company is focusing on the 3PL market and has seen improvements in its global specialty logistics business [50][52] Question: What is the company's approach to capital deployment? - The company prioritizes balanced capital deployment, including investments in business growth, strategic acquisitions, share repurchases, and dividend payments [62][63]

As filed with the Securities and Exchange Commission on November 28, 2025 Registration No. 333-_______ UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 FLORA GROWTH CORP. (Exact Name of Registrant as Specified in Its Charter) Ontario, Canada 2833 Not Applicable (State or other jurisdiction of incorporation or organization) (Primary Standard Industrial Classification Code Number) (I.R.S. Employer Identification No.) 3230 ...

Core Insights - CVS Health's Health Care Benefits segment reported a medical benefit ratio (MBR) of 92.8% in Q3 2025, down from 95.2% in the previous year, indicating improved business performance despite some challenges [1][8] Financial Performance - The improvement in MBR was influenced by the absence of approximately $1.1 billion in premium deficiency reserves (PDR) recorded in Q3 2024, with $174 million of PDR utilized in the first half of 2025 [2] - CVS Health anticipates a full-year 2025 MBR of around 91%, reflecting a cautious outlook on medical cost trends for the remainder of the year [4][8] Market Position and Competitors - CVS Health's stock has increased by 27.2% over the past six months, outperforming the industry average growth of 11.4% [7] - The company is trading at a forward five-year price/sales (P/S) ratio of 0.24, which is lower than the industry average of 0.49, indicating potential undervaluation [9] Analyst Sentiment - Analysts maintain a positive outlook on CVS Health, supported by rising earnings estimates for 2025 and 2026 [10]

Core Insights - McKesson Corporation, based in Irving, Texas, is one of America's oldest businesses with a market capitalization of approximately $105.6 billion, focusing on pharmaceutical distribution, medical supply delivery, and technology solutions [1] Market Performance - Over the past 52 weeks, McKesson's stock has increased by 39.8% and by 51% year-to-date, significantly outperforming the S&P 500 Index, which gained 12.3% and 12.5% in the same periods [2] - The stock has also outperformed the S&P 500 Healthcare Sector SPDR, which saw a 7.5% increase over the past 52 weeks and a 10.9% rise year-to-date [3] Financial Results - For the second quarter of fiscal year 2026, McKesson reported a revenue increase of 10.1% year-over-year, reaching $103.2 billion, aligning with analyst expectations, driven by stronger prescription volumes and broader distribution of oncology and multispecialty products [4] - Earnings per share (EPS) surged 377% annually to $8.92, surpassing expectations, and the management has raised its adjusted EPS outlook for fiscal year 2026 to a range of $38.35 to $38.85 [5] Analyst Outlook - Analysts forecast a 17% EPS growth to $38.66 on a diluted basis for the fiscal year ending in March 2026, with McKesson exceeding analyst expectations for three consecutive quarters [6] - The consensus rating among 16 analysts covering McKesson is "Strong Buy," with 13 "Strong Buy" calls and three "Hold" recommendations [6] - Following the Q2 results, Baird analyst Eric Coldwell raised McKesson's price target to $927 from $873, maintaining an "Outperform" stance, indicating confidence in the company's momentum [7]

Cardinal Health (NYSE: CAH) 2025 Conference Summary Company Overview - **Company**: Cardinal Health - **Date**: November 11, 2025 - **Key Speakers**: Aaron Alt (CFO), Matt Sims (Head of IR) Key Points Financial Performance - Cardinal Health reported strong Q1 results with all five operating segments achieving double-digit profit growth, particularly in the pharma business, which saw a profit increase of 26% [2][3][4] - The company raised its adjusted EPS guidance to $9.65-$9.85, reflecting a year-over-year growth of 17%-20% [4][5] Business Segments - **Pharma Business**: Strong demand and execution, particularly in specialty distribution, contributed significantly to profit growth [2][3] - **Other Business**: The aggregation of smaller businesses (Nuclear Precision Health, At Home, OptiFreight Logistics) saw a profit growth of 60%, partly due to the acquisition of ADSG [3][4] - **Global Medical Products and Distribution (GMPD)**: Experienced revenue growth with the Cardinal Health brand business growing at 6% for two consecutive quarters [4][5][56] Customer Onboarding and Growth Strategy - Cardinal Health onboarded $10 billion in new business in the latter half of the previous year and is on track to onboard an additional $7 billion in the first half of the current year [5][12] - The company is focusing on investing in new customers and enhancing its MSO platforms to drive future growth [5][6] Market Dynamics and Demand - Demand across all segments exceeded expectations, with notable growth in generics and specialty products [9][10] - The company noted a consistent market dynamic, indicating no dislocation between buying and selling, which contributed to strong quarterly results [10][11] Specialty Business Focus - Cardinal Health emphasizes its strength in "otherologies" (rheumatology, urology, gastroenterology) rather than oncology, which is a key differentiator in its specialty business strategy [19][20] - The company aims to leverage its distribution capabilities and technology to enhance partnerships with healthcare providers in these specialty areas [25][26] Competitive Landscape - The medical products business is undergoing competitive changes, with Cardinal Health focusing on improving its GMPD segment to maintain market share against competitors like Medline and McKesson [56][59] - The company is actively seeking opportunities arising from industry transitions, such as acquisitions and partnerships, to enhance its competitive position [60] Operational Efficiency - Cardinal Health is investing in automation and optimizing its distribution network to improve operational efficiency and reduce costs [36][37] - The company is committed to maintaining high service levels while managing costs effectively [37][39] Future Outlook - The company anticipates continued growth in its nuclear precision health business, projecting a long-term profit growth of 10% [74][75] - Cardinal Health remains confident in its long-term guidance, citing its essential role in the American healthcare system and the ongoing demand for its services [49][50] COVID-19 Impact - COVID-19 was noted as a slight headwind in Q1, but overall demand growth offset this impact [78][79] - The company expects COVID-related profits to continue declining, with a focus on broader market dynamics moving forward [79][80] Conclusion Cardinal Health's strong financial performance, strategic focus on specialty and otherologies, and commitment to operational efficiency position the company well for future growth in a competitive healthcare landscape. The ongoing investments in customer onboarding and technology enhancements are expected to drive continued success.

Summary of McKesson's 2025 Conference Call Company Overview - **Company**: McKesson Corporation (NYSE: MCK) - **Event**: UBS Healthcare Conference - **Date**: November 10, 2025 Key Points Industry Insights - **North American Pharmaceutical Business**: McKesson has resegmented its business to provide clarity on strategies, separating specialty oncology from the North American Pharmaceutical segment, which includes the US Pharma and Canadian distribution businesses [3][5][6] - **Market Trends**: The company has observed consistent growth in utilization, driven by demographic trends and innovations in drug development and distribution [7][9] - **Specialty Drugs**: There is a notable shift towards specialty drugs, which are becoming a larger part of the business mix, contributing to improved margins [9][10] Financial Performance - **Operating Expense Leverage**: Over the past five years, McKesson has improved its operating expense leverage by over 1,000 basis points, attributed to investments in automation and technology [17][18] - **Revenue Growth**: The adjusted EPS guidance for the year is between $38.35 and $38.85, representing a growth of 16%-18%, or 18%-20% when excluding prior year gains [63] Strategic Initiatives - **Automation and AI**: McKesson is investing in automation and AI to enhance operational efficiency, with a new distribution center in Ohio being 90% automated [16][18] - **Oncology and Specialty Services**: The company is focused on expanding its oncology services and exploring opportunities in other specialties, particularly in high drug spend areas like retina and ophthalmology [35][44] Pricing and Market Dynamics - **Generic Pricing**: The pricing environment for generics has been stable, with month-to-month variations not significantly impacting long-term strategies [21][22] - **Impact of Legislation**: McKesson does not foresee direct impacts from recent legislative changes regarding drug pricing, as they continue to negotiate fair value for their services [24][25] Future Opportunities - **Clinical Trials and Research**: McKesson sees potential in expanding clinical trial access and management through its Sarah Cannon Research Institute joint venture, which could enhance its oncology platform [33][34] - **New Therapeutic Areas**: The company is exploring opportunities in other therapeutic areas with high innovation and drug spend, beyond oncology and ophthalmology [44][45] Operational Considerations - **Working Capital Management**: McKesson is focused on efficient working capital management, ensuring that fixed fees for services remain unaffected by fluctuations in drug prices [28][29] - **GPO and MSO Dynamics**: The Group Purchasing Organization (GPO) services a wide range of providers, and the company is looking to grow beyond drug distribution into additional service offerings [49] Conclusion - McKesson is strategically positioned to leverage its capabilities in the North American pharmaceutical market, focusing on specialty drugs, operational efficiency through automation, and expanding its oncology services while navigating the evolving regulatory landscape. The company anticipates continued growth and opportunities in high drug spend areas, supported by its investments in technology and clinical services.

Core Insights - McKesson Corporation reported strong adjusted earnings per share (EPS) of $9.86 for Q2 fiscal 2026, exceeding estimates by 10.5% and showing a year-over-year increase of 39.5% driven by operational growth and acquisitions [1] - Total revenues reached $103.15 billion, a 10.1% increase year-over-year, but fell short of estimates by 1.4% [3] - The company raised its fiscal 2026 EPS guidance to $38.35-$38.85, reflecting confidence in demand and growth across its segments [15] Revenue and Earnings Performance - Adjusted EPS of $9.86 beat the Zacks Consensus Estimate of $8.92, with GAAP EPS reported at $8.92 compared to $1.87 in the prior year [1][2] - Revenues of $103.15 billion increased by 10.1% year-over-year, driven by higher prescription volumes and growth in oncology and specialty products [3] - The North American Pharmaceutical segment generated $86.48 billion in revenue, up 8.1% year-over-year, attributed to increased prescription volumes [7] Segment Analysis - The Oncology & Multispecialty segment reported revenues of $12.04 billion, a significant increase of 31.5% year-over-year, with adjusted operating profit rising 71.1% to $397 million [9] - The Prescription Technology Solutions segment saw revenues of $1.38 billion, up 8.8% year-over-year, with adjusted operating profit increasing 19.7% to $261 million [10] - The Medical-Surgical Solutions segment's revenues remained flat at $2.95 billion, with adjusted operating profit up 2.5% to $249 million [11] Financial Metrics - Adjusted gross profit was $3.53 billion, an increase of 8.9% year-over-year, representing 3.4% of net revenues [12] - Adjusted operating income rose 24.9% to $1.57 billion, with an operating margin of 1.5%, expanding nearly 18 basis points year-over-year [13] - Cash and cash equivalents increased to $4 billion from $2.42 billion in the previous quarter, with cumulative net cash from operating activities at $1.5 billion [14] Strategic Initiatives - McKesson is modernizing its distribution through automation and compliance with DSCSA, enhancing its operational capabilities [18] - The company is advancing its portfolio transformation, including plans to spin off the Medical-Surgical Solutions business by the second half of calendar 2027 [18] - New capabilities in high-complexity therapies and rising demand for automated access tools are expected to drive future growth [17]