Core Insights - Artelo Biosciences, Inc. is advancing its clinical-stage pharmaceutical programs with positive human data and upcoming clinical catalysts, focusing on treatments for cancer, pain, and other conditions [1] Business Highlights - Successful completion of a Phase 1 study for ART26.12, showing a favorable safety profile and predictable pharmacokinetics, with plans to initiate a multiple ascending dose study in Q3 2026 [2] - Positive interim Phase 2 results for ART27.13, demonstrating improvements in body weight, lean body mass, and physical activity in patients with cancer anorexia-cachexia syndrome [3] - Received favorable regulatory guidance from the UK MHRA for ART12.11, with plans to initiate human clinical studies in H1 2027 [4] Clinical Progress - ART26.12 has shown sustained analgesic effects comparable to naproxen without tolerance in preclinical models, positioning it as a non-opioid alternative for pain management [5] - ART27.13 has received a Notice of Allowance from the European Patent Office, extending patent protection through December 2041, which has increased partner interest in its development [5] - ART12.11 has demonstrated robust antidepressant-like activity in preclinical studies, with plans for first-in-human studies early next year [5] Financial Results - Research and development expenses for FY 2025 were $5.4 million, down from $6.0 million in FY 2024 [6] - General and administrative expenses increased to $6.0 million in FY 2025 from $4.1 million in the previous year [6] - The net loss for FY 2025 was $12.9 million, or $12.52 per share, compared to a net loss of $9.8 million in FY 2024 [6] - Cash and investments totaled $0.6 million as of December 31, 2025 [6] Product Information - ART26.12 is a lead FABP5 inhibitor aimed at treating chemotherapy-induced peripheral neuropathy, with a favorable safety profile and dosing flexibility [8] - ART27.13 is a cannabinoid receptor agonist targeting cancer-related anorexia and cachexia, showing a mean weight gain of over 6% in the top dose group compared to a 5% loss in the placebo group [9][10] - ART12.11 is a proprietary cocrystal composition of CBD and TMP, with enhanced pharmacokinetics and plans for clinical studies in 2026 [11]

AbbVie to Present at the TD Cowen 46th Annual Health Care Conference [Accessibility Statement] Skip NavigationNORTH CHICAGO, Ill., Feb. 24, 2026 /PRNewswire/ -- AbbVie (NYSE: ABBV) will participate in the TD Cowen 46th Annual Health Care Conference on Tuesday, March 3, 2026. Management will participate in a fireside chat at 10:10 a.m. Central Time.A live audio webcast of the presentation will be accessible through AbbVie's Investor Relations website at [investors.abbvie.com]. An archived edition of the sess ...

Group 1 - Shares of Novo Nordisk and Eli Lilly experienced a decline on Tuesday due to a report indicating that price cuts are forthcoming for their popular weight-loss drugs [1]

The Danish drugmaker released a promising update about a trial in China, but that didn't end a rough run for shares. ...

Core Viewpoint - Helus Pharma has appointed Dr. Freda Lewis-Hall to its Board of Directors and as Chair of the Scientific Advisory Committee, aiming to enhance its clinical development strategy and regulatory engagement for its novel serotonergic agonist portfolio [2][6]. Company Overview - Helus Pharma is a clinical stage pharmaceutical company focused on developing novel serotonergic agonists (NSAs) to address serious mental health conditions such as depression and anxiety [9][10]. - The company operates in Canada, the United States, the United Kingdom, and Ireland [11]. Leadership Appointment - Dr. Freda Lewis-Hall brings over 40 years of experience in clinical care, research, and corporate leadership, having previously served as Executive Vice President and Chief Medical Officer at Pfizer [3][4]. - Her role will involve providing leadership in scientific, clinical, and regulatory governance across Helus' portfolio, advising on discovery opportunities and clinical development strategies [6][7]. Clinical Development Focus - Helus Pharma is currently developing HLP003, a proprietary NSA in Phase 3 clinical development for major depressive disorder, which has received Breakthrough Therapy Designation from the U.S. FDA [10]. - HLP004, another proprietary NSA, is in Phase 2 for generalized anxiety disorder [10]. Strategic Goals - The company aims to improve the treatment landscape for mental health through its innovative NSAs, focusing on delivering meaningful outcomes for patients and long-term value for stakeholders [6][10].

Group 1 - Danish drugmaker Novo Nordisk plans to reduce U.S. list prices of its diabetes and weight-loss drugs Ozempic and Wegovy by up to 50% starting next year [1] - The decision comes amid increasing scrutiny and pressure on drug pricing in the U.S. healthcare market [1] - The price cut is expected to significantly impact the accessibility of these medications for patients [1] Group 2 - Ozempic and Wegovy are considered blockbuster drugs, indicating their substantial sales and market presence [1] - The move may reflect a broader trend in the pharmaceutical industry towards more competitive pricing strategies [1] - Novo Nordisk's pricing strategy could influence other companies in the healthcare sector to reconsider their pricing models [1]

Core Insights - Paratek Pharmaceuticals announced positive top-line results from two animal studies supporting the development of NUZYRA for the treatment of pulmonary anthrax [1][3] - The studies involved a non-human primate model and a rabbit model, with the latter's data to be presented in Spring 2026 [1][3] - The positive findings have led to additional procurement of NUZYRA under the Project BioShield contract with BARDA [2][6] Group 1: Study Results - The NHP study data were previously presented at a conference, while pivotal rabbit study data will be shared at an upcoming conference [1] - These studies confirm NUZYRA's therapeutic efficacy in treating pulmonary anthrax, building on previous findings for post-exposure prophylaxis [3] Group 2: Contract and Procurement - The BARDA contract, valued at approximately $304 million, supports the development of NUZYRA and includes procurement of up to 10,000 treatment courses for anthrax [6] - Oral NUZYRA tablets associated with this procurement were produced in the U.S. as part of the company's onshoring initiative [2][6] Group 3: Company Overview - Paratek Pharmaceuticals focuses on developing specialty therapies for public health threats and unmet medical needs, with products including NUZYRA and XHANCE [5] - The company is privately held by B-FLEXION Life Sciences [5]

Core Insights - Novartis announced new real-world studies on Pluvicto™ for metastatic prostate cancer, utilizing data from the PRECISION platform, to be presented at the ASCO Genitourinary Cancers Symposium [1] Group 1: Efficacy of Pluvicto - Pluvicto demonstrated a median progression-free survival (PFS) of 13.5 months in taxane-naïve mCRPC patients who had received at least one ARPI, with longer PFS observed in those treated after one ARPI (15.8 months) compared to multiple ARPIs (12.7 months) [2][3] - The findings align with the PSMAfore trial, which showed that Pluvicto more than doubled median rPFS compared to a change in ARPI (11.6 months vs. 5.6 months) [3] Group 2: Subsequent Therapies - A study indicated that mCRPC patients achieved meaningful clinical responses with systemic therapies after discontinuing Pluvicto, with median PFS of 8.6 months for all subsequent therapies [5][6] - Patients receiving ARPI after Pluvicto had a median PFS of 10.7 months, while those receiving taxane had a median PFS of 7.2 months [6] Group 3: Treatment Patterns and Guidelines - Real-world evidence showed significant gaps in guideline adherence for metastatic hormone-sensitive prostate cancer (mHSPC), with 39.2% of men receiving ADT monotherapy instead of the recommended combination therapy [8] - The data highlights an opportunity for improved patient care through adherence to clinical guidelines [8] Group 4: PRECISION Data Platform - The PRECISION platform harmonizes data from over 56,500 patients with metastatic prostate cancer to generate real-world evidence studies that inform clinical decisions [9]

WARREN, N.J., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Aquestive Therapeutics, Inc. (NASDAQ: AQST) (“Aquestive” or the “Company”), a pharmaceutical company advancing medicines to bring meaningful improvement to patients' lives through innovative science and delivery technologies, today announced that it will report results for the fourth quarter ended December 31, 2025 and provide an update on recent developments in its business after market close on Wednesday, March 4, 2026. Management will host a conference call ...

RICHMOND, Va., Feb. 24, 2026 (GLOBE NEWSWIRE) -- Indivior Pharmaceuticals, Inc. (Nasdaq: INDV) today announced that it will participate in the following upcoming investor conferences: Barclays 28th Annual Global Healthcare Conference – Miami, FLJoe Ciaffoni, Chief Executive Officer, will host 1x1 / group meetings on Tuesday, March 10th. Joe Ciaffoni will also participate in a fireside chat on Tuesday, March 10th at 2:00 p.m. U.S. EST. Interested investors should contact their Barclays representative to sche ...