Core Concept - Organ chips represent a significant advancement in biomedical research, utilizing human cells to create miniaturized organ models for drug testing and disease research, offering a more accurate alternative to traditional animal models [4][6][7]. Group 1: Technology Overview - Organ chips are built on a foundation of microfluidic technology, integrating human cells and biological materials to simulate organ functions and responses [2][3]. - The first fully functional organ chip, the "lung chip," was developed around 2009, and research in this field has been ongoing for over a decade in China [3][5]. - These chips can replicate complex physiological environments, allowing for precise drug testing and disease modeling [3][6]. Group 2: Advantages Over Traditional Methods - Organ chips significantly reduce the reliance on animal testing, addressing ethical concerns and providing more relevant data for human biology [4][6]. - They offer a high-throughput capability, enabling extensive data analysis and reducing the time required for drug testing from 90-180 days to just 6 days for 100 compounds [6][7]. - The cost of using organ chips is only 10% to 20% of traditional animal models, making them a cost-effective solution for drug development [7]. Group 3: Market Potential - The global organ chip market is projected to grow at a compound annual growth rate (CAGR) of 31.2% from 2024 to 2030, indicating strong future demand for this technology [8]. Group 4: Challenges Ahead - Despite the promising potential of organ chips, the transition from scientific research to practical application faces challenges that need to be addressed [9].