Investor Presentation February 2025 Disclaimers Forward-Looking Statements This presentation contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. All statements contained in this presentation that do not relate to matters of historical fact should be considered forward-looking statements, including without limitation statements regarding our future results of operations and financial position, including the underlying assumptions of any such project ...

Marpai, Inc. Secures Major Strategic Wins for MarpaiRx, Adding Over 19,000 Lives and Accelerating High-Growth Platform Expansion [Accessibility Statement] Skip NavigationNew Client Momentum Highlights Rapid Adoption of Marpai's Disruptive, Scalable Healthcare Platform Positioned to Drive Exponential Revenue Growth and Long-Term Shareholder ValueTAMPA, Fla., Feb. 23, 2026 /PRNewswire/ -- Marpai, Inc. ("Marpai" or the "Company") (OTCQX: MRAI), a leader in innovative healthcare technology, Third-Party Administ ...

Group 1 - CVS Health Corporation (NYSE:CVS) is the top stock pick for billionaire Larry Robbins, accounting for 13.76% of his portfolio, valued at $617.96 million [1] - Despite a decrease in fourth-quarter profit, CVS exceeded Wall Street expectations, indicating early success in restructuring efforts after a challenging 2024 [2] - Adjusted EPS for CVS was $1.09, down from $1.19 a year earlier but above the consensus estimate of $0.99, with total revenue increasing from $97.70 billion to $105.70 billion due to higher prescription volumes and assets acquired from Rite Aid [3] Group 2 - For 2026, CVS reaffirmed its revenue guidance of at least $400.00 billion and adjusted EPS guidance of $7.00–$7.20, reflecting a focus on execution discipline rather than aggressive growth [4] - The Aetna insurance unit reported a medical loss ratio of 94.80%, slightly better than expected, despite pressures from Medicare Advantage cost trends related to the Inflation Reduction Act [4] - CVS operates as a diversified healthcare company, integrating insurance, pharmacy benefit management, retail pharmacies, and clinical services across the United States [6]

Financial Data and Key Metrics Changes - In Q4 2025, CVS Health reported adjusted operating income of $2.6 billion and adjusted earnings per share (EPS) of $1.09, with full-year adjusted EPS of $6.75 and operating cash flow of $10.6 billion, exceeding initial expectations by approximately 15% [5][6][24]. - Full-year revenue for 2025 was over $400 billion, with Q4 revenue exceeding $105 billion, an increase of over 8% year-over-year [23][24]. Business Line Data and Key Metrics Changes - The healthcare benefits segment generated over $36 billion in revenue for Q4, a 10% increase year-over-year, but reported an adjusted operating loss of $676 million due to changes in the Medicare Part D program [25][26]. - The health services segment saw revenues of over $51 billion, a 9% increase year-over-year, with adjusted operating income of approximately $1.9 billion [28]. - The pharmacy and consumer wellness segment generated nearly $38 billion in revenue, a 12% increase year-over-year, with same-store pharmacy sales growing over 19% [29][30]. Market Data and Key Metrics Changes - The company ended 2025 with approximately 26.6 million medical members, a slight decline from the previous year, primarily due to losses in individual exchange and government businesses [25][26]. - Aetna received the inaugural Press Ganey Health Plan of the Year award, recognizing its high-quality offerings and technological innovation [7]. Company Strategy and Development Direction - CVS Health aims to simplify the healthcare experience and make it more affordable, with a commitment to becoming America's most trusted healthcare company [5]. - The company is focused on improving margins in its Medicare business while advocating for better funding to ensure adequate access for seniors [8][40]. - CVS Health is committed to leveraging its diversified business model to unlock earnings power and drive shareholder value [6][21]. Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's momentum entering 2026, expecting another strong year of progress despite elevated medical cost trends [33][34]. - The company remains focused on addressing the challenges of cost, complexity, and fragmentation in the U.S. healthcare system [15][21]. Other Important Information - CVS Health's pharmacy businesses are adapting to regulatory changes while maintaining durable margins, emphasizing the importance of transparency and competition in the pharmaceutical supply chain [12][19]. - The company has successfully transitioned to a cost-based reimbursement model, enhancing transparency and stability in the pharmacy market [14][31]. Q&A Session Questions and Answers Question: Impact of Medicare Advantage rates on margins - Management acknowledged the Advanced Rate Notice's impact on Aetna but remains committed to improving Medicare Advantage margins and believes the business is well-positioned despite the preliminary rates [37][39][45]. Question: Regulatory impact on PBM negotiations - Management indicated that while they cannot discuss specifics regarding the FTC, they believe the PBM value remains intact and that they are prepared for upcoming regulatory changes [51][53]. Question: Medicaid rates and expectations for 2026 - Management reported that the Medicaid business is performing in line with expectations and emphasized ongoing advocacy for adequate rates while maintaining operational excellence [72][74].

Financial Data and Key Metrics Changes - The Cigna Group reported full-year adjusted revenue of $275 billion, reflecting an 11% growth, and adjusted earnings per share of $29.84, a 9% increase [8][30] - The company recorded after-tax special item charges of $483 million or $1.82 per share in the fourth quarter [5] Business Line Data and Key Metrics Changes - Evernorth's specialty and care services business achieved 14% adjusted revenue growth, generating $26.7 billion in revenue [18][31] - The pharmacy benefit services business within Evernorth delivered $36.3 billion in revenue and $1.2 billion in adjusted earnings [31] Market Data and Key Metrics Changes - The company noted a 13% year-over-year growth in the number of specialty prescriptions in 2025 [18] - Cigna Healthcare's adjusted revenues for the fourth quarter reached $11.2 billion, with pre-tax adjusted earnings of $734 million [32] Company Strategy and Development Direction - The Cigna Group is focused on evolving its business model to enhance affordability and transparency, particularly through a new rebate-free pharmacy benefits model [10][25] - The company aims to leverage partnerships and innovations to drive down healthcare costs and improve access to medications [12][22] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to navigate a dynamic healthcare environment and emphasized a commitment to lowering healthcare costs [10][17] - The outlook for 2026 includes expected consolidated adjusted revenues of approximately $280 billion and adjusted earnings per share of at least $30.25 [33][38] Other Important Information - The company announced a global settlement with the Federal Trade Commission, which is expected to provide $7 billion in out-of-pocket cost relief over the next 10 years for customers [9] - Cigna's strategic investment in Shields Health Solutions aims to expand specialty capabilities to serve hospitals and health systems [8][31] Q&A Session Summary Question: Discussion on PBM legislation and its economic implications - Management indicated that the margin profile for the pharmacy benefit management (PBM) model is expected to remain similar despite the new legislation and FTC settlement [40][43] Question: Adoption of the new pricing model - The entire Cigna Healthcare fully insured book will adopt the new pricing model by 2027, with at least 50% of the Evernorth business expected to transition by the end of 2028 [48][52] Question: Specialty business growth drivers - The specialty business experienced 14% top-line growth, driven by strong demand in areas such as inflammatory, asthma, and allergy treatments, with expectations for continued growth in the biosimilar market [75][78]

Financial Data and Key Metrics Changes - The Cigna Group reported full-year adjusted revenue of $275 billion, reflecting an 11% growth year-over-year [8] - Adjusted earnings per share (EPS) for the full year reached $29.84, a 9% increase compared to the previous year [8][17] - The company recorded after-tax special item charges of $483 million, equating to $1.82 per share [4][5] Business Line Data and Key Metrics Changes - Evernorth's specialty and care services business generated $26.7 billion in revenue, marking a 14% year-over-year increase [31] - The pharmacy benefit services business within Evernorth delivered $36.3 billion in revenue, with adjusted earnings of $1.2 billion [31] - Cigna Healthcare achieved adjusted revenues of $11.2 billion in the fourth quarter, with pre-tax adjusted earnings of $734 million [32] Market Data and Key Metrics Changes - The company reported a 13% year-over-year growth in the number of specialty prescriptions [18] - The specialty pharmacy market is projected to grow significantly, with expectations of long-term average annual income growth of 8%-12% [75] - Approximately 90% of all prescriptions filled in the U.S. are generic, contributing to lower overall pharmacy spending [15] Company Strategy and Development Direction - The Cigna Group is focused on evolving its business model to enhance affordability and transparency in healthcare, particularly through a new rebate-free pharmacy benefits model [10][25] - The company aims to leverage partnerships and innovative solutions to improve patient access and lower costs, including collaborations with various healthcare providers [14][22] - Strategic investments in specialty capabilities and care services are intended to position the company for sustainable growth in a rapidly changing environment [8][31] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to navigate a dynamic healthcare landscape, emphasizing a commitment to lowering healthcare costs and improving access to quality care [10][12] - The outlook for 2026 includes projected consolidated adjusted revenues of approximately $280 billion and adjusted EPS of at least $30.25 [33][34] - Management highlighted the importance of addressing underlying cost drivers in healthcare, including rising demand due to chronic conditions and aging populations [11] Other Important Information - The company announced a global settlement with the Federal Trade Commission, which is expected to provide $7 billion in out-of-pocket cost relief over the next 10 years for customers [9] - Cigna's new pharmacy benefit model is designed to ensure the lowest out-of-pocket costs for consumers and enhance support for local pharmacies [61] Q&A Session Summary Question: Discussion on PBM legislation and margin profile - Management indicated that the margin profile for the pharmacy benefit services (PBM) will remain similar despite the new model and regulatory changes, with a potential maximum impact of 1% on the effective tax rate due to the relocation of GPO capabilities [40][45] Question: Adoption of the new pricing model - The entire Cigna Healthcare fully insured book is expected to adopt the new pricing model by 2027, with at least 50% of the Evernorth business adopting it by the end of 2028 [48][51] Question: Specialty business growth drivers - The specialty business is experiencing strong growth, driven by increased prescriptions and a focus on biosimilars, with expectations for continued momentum in 2026 [75][78]

Financial Data and Key Metrics Changes - The Cigna Group reported full-year adjusted revenue of $275 billion, reflecting an 11% growth year-over-year [6][28] - Adjusted earnings per share (EPS) for the full year 2025 reached $29.84, a 9% increase compared to the previous year [6][30] - The company recorded after-tax special item charges of $483 million, equating to $1.82 per share [3][4] Business Line Data and Key Metrics Changes - Evernorth's specialty and care services business generated $26.7 billion in revenue, marking a 14% year-over-year growth [28] - The pharmacy benefit services business within Evernorth delivered $36.3 billion in revenue, with adjusted earnings of $1.2 billion [28] - Cigna Healthcare achieved adjusted revenues of $11.2 billion in Q4 2025, with pre-tax adjusted earnings of $734 million [30] Market Data and Key Metrics Changes - The company reported a 13% year-over-year growth in the number of specialty prescriptions in 2025 [15] - The specialty pharmacy market is projected to grow significantly, with a $400 billion-plus addressable market growing at a high single-digit secular growth rate [70] Company Strategy and Development Direction - Cigna Group is focused on evolving its business model to enhance customer experience and affordability, including a new rebate-free pharmacy benefits model [10][22] - The company aims to leverage partnerships and innovations to drive down healthcare costs and improve access to medications [11][12] - Strategic investments in specialty capabilities and pharmacy benefit services are intended to position the company for sustained growth [6][28] Management's Comments on Operating Environment and Future Outlook - Management expressed confidence in the company's ability to navigate a dynamic healthcare environment and achieve sustained growth [5][13] - The outlook for 2026 includes projected consolidated adjusted revenues of approximately $280 billion and adjusted EPS of at least $30.25 [30][31] - The company anticipates continued investment in infrastructure to support its new pharmacy benefits model, with a focus on affordability and transparency [31][66] Other Important Information - The company announced a global settlement with the Federal Trade Commission, which is expected to provide $7 billion in out-of-pocket cost relief over the next 10 years for customers [7][8] - Cigna Group returned over $5 billion to shareholders through dividends and share repurchases in 2025 [13] Q&A Session Summary Question: Discussion on PBM legislation and margin profile - Management indicated that the margin profile for the pharmacy benefit services (PBS) will remain similar despite the new model and regulatory changes, with no expected change in the growth algorithm [37][39] Question: Adoption of new pricing model - The entire Cigna Healthcare fully insured book is expected to adopt the new pricing model by 2027, with at least 50% of the Evernorth business adopting it by the end of 2028 [44][48] Question: Specialty business growth drivers - The specialty business experienced 14% top-line growth, driven by strong demand in various therapeutic areas and the increasing adoption of biosimilars [70][71]

Core Insights - Cigna Corp's Express Scripts has settled claims from the U.S. Federal Trade Commission regarding antitrust violations in insulin pricing practices, agreeing to changes that aim to reduce costs for patients, insurers, and small pharmacies [1][2] Group 1: Settlement Details - The settlement aligns with the Trump administration's efforts to lower drug costs and allows the FTC to reduce a case initiated by the Biden administration against Express Scripts, UnitedHealth Group's Optum, and CVS Health's Caremark, with ongoing cases against Optum and Caremark [2] - The 10-year agreement restricts Express Scripts from engaging in practices that contribute to high costs, such as retaining rebate payments from drugmakers based on list prices, potentially saving patients up to $7 billion over the decade [4] - Express Scripts is now legally bound to comply with the settlement terms and will be monitored for three years [4] Group 2: Industry Context - Pharmacy benefit managers have faced scrutiny for pricing practices, with the FTC accusing them of directing patients and insurers towards higher-priced drugs to maximize profits [5] - The settlement requires Express Scripts to collaborate with local pharmacies and disclose drug costs to employers annually [5] - Cigna's insurance business primarily manages plans for employers, and the settlement mandates that direct-to-consumer drug purchases through the planned TrumpRX platform count towards copays and deductibles in standard employer plans [6] Group 3: Industry Trends - In recent years, CVS, UnitedHealth, and Cigna have introduced new pricing models aimed at increasing transparency regarding discounts, fees, and drug costs, shifting revenue models towards administrative fees rather than hidden reimbursements from drugmakers [7]

Core Insights - The proposed regulation by the U.S. Department of Labor aims for "radical transparency" from Pharmacy Benefit Managers (PBMs), which could significantly impact the profitability of major health companies like UnitedHealth, CVS, and Humana [2][3][5] Group 1: Regulatory Changes - The new DOL regulation requires PBMs to disclose their compensation to self-insured group health plans, affecting approximately 90 million Americans [3] - The regulation targets hidden fees and distorted incentives within the healthcare system, emphasizing that transparency will benefit American workers and their families [3] - The timing of the proposed rule coincides with increased scrutiny over how PBMs manage rebates, particularly allegations of using "shell companies" to obscure fees [3][4] Group 2: Financial Practices of PBMs - Reports indicate that PBMs often claim to pass through 100% of rebates to customers but may instead funnel money through subsidiaries, including those in "ghost offices" in Ireland and Switzerland [4] - The DOL regulation is designed to close loopholes by ensuring that compensation through Group Purchasing Organizations (GPOs) or rebate aggregators is disclosed to plan fiduciaries [5] - Key financial practices under scrutiny include spread pricing, rebates, and clawbacks, which are critical to understanding the financial dynamics between PBMs, health plans, and pharmacies [6]

TAMPA, Fla., Jan. 27, 2026 /PRNewswire/ -- Marpai, Inc. ("Marpai" or the "Company") (OTCQX: MRAI), a leader in innovative healthcare technology, Pharmacy Benefit Management (PBM) and Third-Party Administration (TPA) services, announced the hiring of Mimi Davis as President of MarpaiRx. Davis, a distinguished leader in the pharmacy services sector, will oversee the strategic expansion and operational scaling of Marpai's pharmacy benefit offerings. Davis joins Marpai from Knipper Health, where she served as E ...