Core Viewpoint - The "2025 Shanghai International Computational Biology Innovation Competition" has been officially launched to promote the development of computational biology in Shanghai, with a focus on attracting participation from students and researchers through campus outreach activities [1][14]. Group 1: Competition Overview - The competition is organized by the Shanghai Biomedicine Technology Industry Promotion Center and aims to implement the "Shanghai Computational Biology Innovation Development Action Plan (2023-2025)" [1]. - The first campus outreach event took place on June 19, 2025, at Shanghai Jiao Tong University and Shanghai University of Science and Technology, successfully engaging students [1][12]. Group 2: Competition Challenges - The competition focuses on the HCAR1 receptor, a promising target for anti-tumor drugs, which currently lacks high-activity intervention drugs [4][6]. - Participants are required to use AI calculations to select potential drug candidates based on known protein sequences and structures, aiming to accelerate drug discovery and clinical translation [6][8]. Group 3: Experience Sharing - Outstanding teams from the previous year's competition shared their experiences, providing valuable insights on topic selection, teamwork, and overcoming technical challenges [10][12]. - The sharing session was well-received, with students actively engaging in discussions about computational models, algorithms, and support policies for award-winning teams [12]. Group 4: Impact and Future Activities - The successful execution of the campus outreach event has effectively expanded the competition's influence and fostered a strong atmosphere for innovation in computational biology among top universities in Shanghai [14]. - As more outreach activities are planned, the competition is expected to stimulate broader innovation and contribute significantly to the development of the computational biology field [14].