Group 1 - The article discusses the development of a "bionic band-aid" using snail mucus, which offers new hope for treating diabetic foot ulcers [2][3] - Snail mucus contains proteins and polysaccharides, with glycosaminoglycans being the main effective component that promotes wound healing [2][3] - The structure of glycosaminoglycans varies among different snail species, with the "French snail" having a newly discovered type that resembles human extracellular matrix components [3] Group 2 - The bionic band-aid is designed to create a suitable healing environment for tissue growth by constructing a three-dimensional gel network using snail-derived glycosaminoglycans and gelatin [3] - The band-aid incorporates dynamic borate ester technology to release tea polyphenols from tea tree plants when glucose levels rise at the wound site, addressing issues of oxidation and low bioavailability [3][4] - In experiments on diabetic mouse models, the band-aid showed a 72.6% epidermal regeneration rate after 7 days, more than double that of the saline group, with collagen fiber arrangement closer to normal skin [3][4]

Group 1 - The core idea of the article is the development of a "bionic band-aid" using snail mucus, which offers new hope for treating diabetic foot ulcers and other difficult-to-heal wounds [2][3][4] - Snail mucus contains proteins and polysaccharides, including glycosaminoglycans, which are the main effective components that promote wound healing [2][3] - The newly discovered glycosaminoglycans in the mucus of the "French snail" (Helix aspersa) have a structure similar to those found in human extracellular matrix, making them suitable for aiding skin cell growth [3] Group 2 - The bionic band-aid is constructed using snail-derived glycosaminoglycans and gelatin to create a three-dimensional gel network that mimics the human extracellular matrix, providing a conducive environment for cell growth [3] - The band-aid incorporates dynamic borate ester technology to anchor tea polyphenols from tea tree plants, allowing for controlled drug release in response to elevated glucose levels at the wound site, addressing issues of oxidation and bioavailability [3] - In experiments with diabetic mouse models, the band-aid showed a 72.6% epidermal regeneration rate after 7 days, more than double that of the saline group, with collagen fiber arrangement closer to normal skin [3][4] Group 3 - The band-aid also helps to calm an overactive immune system, reducing inflammatory factor levels by over 50%, thereby breaking the vicious cycle of inflammation and tissue necrosis [4] - It significantly inhibits bacterial colonization at the wound site, further promoting wound healing [4]