创新型环脂肽类抗生素YB211
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九芝堂:九芝堂美科的人骨髓间充质干细胞注射液治疗孤独症的临床试验已于2025年8月26日召开启动会
Zheng Quan Ri Bao· 2026-02-09 12:12
Core Viewpoint - The company, Jiuzhitang, is actively engaged in the research and development of innovative drugs, including the anticoagulant YB209 and the antibiotic YB211, as well as stem cell projects [2] Group 1: R&D Projects - The YB209 project has completed the development and validation of methods for immunogenicity research, and has finished the closing of Phase I clinical trials [2] - The YB211 project has completed the preparation of clinical samples, conducted two stages of reproductive toxicity tests, initiated pharmacokinetics-pharmacodynamics (PK-PD) studies, and has fully launched Phase II clinical trials with subject enrollment [2] Group 2: Clinical Trials - The clinical trial for Jiuzhitang Meike's allogeneic bone marrow mesenchymal stem cell therapy for ischemic stroke has completed enrollment of all 45 subjects in Phase IIa [2] - The clinical trial for bone marrow mesenchymal stem cell injection for autoimmune pulmonary alveolar proteinosis has also completed enrollment of all 10 subjects [2] - A clinical trial for bone marrow mesenchymal stem cell injection for autism was initiated on August 26, 2025, following the kickoff meeting [2]