研究人员用三色正交上转换纳米颗粒取代了传统的上转换纳米颗粒，制备出了三色上转换隐形眼镜，可 以将三种不同光谱的近红外光转换成红、绿、蓝三基色的可见光。实验证明，通过佩戴三色上转换隐形 眼镜，人类志愿者可有效识别三种波长的近红外光，感知多种近红外色彩。 研究人员表示，该技术在医疗、信息处理及视觉辅助技术领域具有广泛应用前景。 22日，记者从中国科学技术大学获悉，该校生命科学与医学部薛天、马玉乾团队与国内外科研机构合 作，制备出高透明、高转化效率的上转换隐形眼镜，可实现人类近红外时空色彩图像视觉能力。相关研 究成果5月22日在线发表在国际期刊《细胞》上。 人类肉眼可感知的可见光仅占电磁波谱很小的一部分。此前，研究团队与合作者将一种可以把近红外光 转换为可见光的上转换纳米颗粒注射到动物视网膜中，首次实现哺乳动物的裸眼近红外图像视觉能力， 研究成果于2019年发表在《细胞》。但该研究的眼内注射在人体应用中受限，如何通过非侵入性方式实 现近红外视觉，是该技术实用化的关键挑战。 高分子聚合材料制备的软性透明隐形眼镜提供了一个可佩戴式解决方案。为此，研究人员对上转换纳米 颗粒进行表面修饰，提高它们在高分子聚合材料中的均匀分 ...

Core Viewpoint - The article discusses the development of wearable near-infrared (NIR) upconversion contact lenses (UCL) that enable humans to perceive NIR images, expanding the visual spectrum beyond the visible light range [3][9]. Group 1: Research Development - A research team from multiple institutions developed UCL that possess suitable optical properties, hydrophilicity, flexibility, and biocompatibility, allowing for the perception of NIR spatial and temporal color images [3][5]. - The UCL achieved a high doping ratio (7-9%) of upconversion nanoparticles (UCNP) while maintaining over 90% transparency in the visible light spectrum, significantly outperforming previously reported materials [5][6]. Group 2: Functional Capabilities - Mice wearing UCL were able to perceive NIR light and distinguish different temporal frequencies and orientations of NIR information [6]. - Human volunteers wearing UCL could see a range of NIR light intensities and accurately identify time-encoded information [6][9]. Group 3: Technological Innovations - The research team developed a wearable eyeglass system integrated with UCL to enhance spatial resolution, allowing volunteers to recognize complex NIR patterns with clarity similar to visible light vision [6][9]. - The use of trichromatic UCNP in the UCL enables the conversion of three different NIR wavelengths into red, green, and blue visible light, facilitating the perception of multi-spectral NIR colors [7][9]. Group 4: Future Applications - This technology has potential applications in medical fields, information processing, and visual assistance technologies, and may offer new solutions for treating visual disorders such as color blindness [9][12]. - The research emphasizes the need for further optimization, including improving upconversion efficiency and achieving directional emission of light from the lenses [12].