Core Viewpoint - BGI Genomics, a leading gene testing company in China, reported its first annual loss since its IPO in 2017, with a net profit of -9.03 billion yuan in 2024, marking a significant decline from a profit of 20.9 billion yuan in 2020 [2][3][4]. Financial Performance - In 2024, BGI Genomics' revenue was 38.67 billion yuan, a decrease of 11.1% year-on-year, and its net profit turned negative for the first time since listing [2][3]. - The company's Q1 2024 revenue was 6.72 billion yuan, down 18.18% year-on-year, with a net loss of 52.7 million yuan, a decline of 524.87% [2]. - Revenue has halved compared to its peak of 83.97 billion yuan in 2020 [3]. Business Segments - BGI Genomics operates five main business segments: reproductive health services (29.7%), tumor and chronic disease prevention services (16.16%), infection prevention services (1.88%), multi-omics big data services (17.26%), and precision medicine testing services (34.37%) [3]. - Only the tumor prevention service segment saw a revenue increase of 19.02% in 2024, while all other segments experienced declines, with infection prevention services plummeting by 85.91% [3]. Strategic Adjustments - The company is undergoing strategic adjustments, including the closure of some overseas laboratories due to unfavorable market conditions, leading to a 48.47 million yuan impairment provision for these assets [4]. - BGI Genomics has increased its R&D investment to 6.77 billion yuan in 2024, a 10.20% increase, representing 17.51% of total revenue [4]. Industry Context - The gene testing industry is facing intense competition and price wars, with 19 out of 39 listed companies in the in vitro diagnostics (IVD) sector reporting losses in the past year [6]. - BGI Genomics' gross margin for genomic applications was 41.81% in 2024, down 7.9% year-on-year, with a significant drop in the gross margin for precision medicine testing services by 12.82% [6][7]. Future Outlook - Despite current challenges, there are growth opportunities in personalized tumor prevention services and domestic reproductive health services due to China's large population base [8]. - The company is exploring AI applications in its services, having developed its own AI model, GeneT, for testing analysis, and is collaborating with major hospitals and laboratories [8]. Market Performance - BGI Genomics' stock price has significantly declined from its peak of 194.2 yuan per share in 2020, closing at 46.88 yuan per share as of April 28, 2024, with a total market capitalization of 194.94 billion yuan [9].

Core Viewpoint - The company is experiencing a decline in revenue and net profit for 2024, with expectations for improvement driven by cost control and AI integration in the future [1][2][3] Financial Performance - 2024 revenue, net profit attributable to parent, and net profit excluding non-recurring items are projected at 38.67 billion, -9.03 billion, and -9.19 billion respectively, showing year-on-year declines of -11.1%, -1072%, and -1091% [1] - For Q1 2025, revenue, net profit attributable to parent, and net profit excluding non-recurring items are expected to be 6.72 billion, -0.53 billion, and -0.63 billion respectively, with year-on-year declines of -18%, -525%, and -2879% [1] - The 2024 performance aligns with expectations, but Q1 2025 shows increased pressure on net profit growth due to extended customer payment cycles and rising expense ratios [1] Business Segments - The reproductive health business in 2024 saw a revenue decline of 2.5% year-on-year, totaling 11.49 billion, influenced by fertility rates and testing prices [1] - The company is expanding its first and third-level prevention services, with notable revenue growth in carrier screening (+12.3%), chromosome abnormality detection (+2.4%), newborn genetic disease screening (+47.4%), and hereditary disease testing (+53.1%) [1] - Revenue from tumor and chronic disease prevention in 2024 reached 6.25 billion, reflecting a stable growth of 19.0% year-on-year, driven by government collaboration and industry-academia cooperation [1] Multi-Omics and Precision Medicine - Multi-omics big data service revenue in 2024 was 6.67 billion, down 5.6% year-on-year, primarily due to international geopolitical factors affecting the Americas [2] - Precision medicine revenue for 2024 was 13.29 billion, also down 5.6% year-on-year, largely due to a significant decline in COVID-related revenue; excluding this, the revenue grew by 22.4% year-on-year [2] Expense and Profitability Metrics - In 2024, the sales, management, R&D, and financial expense ratios were 26.12%, 10.59%, 15.68%, and -1.30%, showing increases of 2.29, 1.42, 3.52, and a decrease of 0.25 percentage points year-on-year [2] - For Q1 2025, these ratios were 24.22%, 11.02%, 17.46%, and -4.09%, with year-on-year changes of +3.53, -1.11, +4.51, and -2.85 percentage points [2] - The gross profit margins for 2024 and Q1 2025 were 41.47% and 43.55%, reflecting declines of 8.43 and 5.65 percentage points year-on-year, attributed to lower margins in certain business segments [2] Future Outlook - The company has adjusted its revenue expectations for the reproductive health business downward while increasing projections for sales and R&D expense ratios [3] - Revenue forecasts for 2025-2027 are set at 42.6 billion, 47.4 billion, and 52.6 billion, with net profit attributable to parent at 0.28 billion, 0.76 billion, and 1.01 billion respectively [3] - The company maintains a target price of 52.19, reflecting a 5.1x price-to-sales ratio for 2025, consistent with industry averages [3]