Core Viewpoint - The recognition of the children's age-specific care brand "Rabbit Head Mama" as a provincial "specialized, refined, and innovative" small and medium-sized enterprise highlights the company's commitment to independent research and innovation, particularly in the development of the self-researched ingredient "Ola Flu" and related foundational research, marking a significant advancement in the children's care segment [1][3][7]. Group 1: Company Overview - Rabbit Head Mama was established in 2018 and focuses on children's oral and skin health, guided by the principle of "love and science" [3]. - The company has invested over 100 million in establishing a research and development center in Hangzhou, which includes 10 specialized laboratories aligned with CNAS standards [3]. - Rabbit Head Mama has accumulated nearly 40 proprietary patents and has been recognized as a national high-tech enterprise and a high-tech research and development center in Hangzhou [3]. Group 2: Technological Innovations - The company has gained attention for its breakthrough in the domestic research of "Ola Flu," which has been reported by major media outlets for overcoming a 60-year technology monopoly [6][7]. - In July 2024, Rabbit Head Mama successfully synthesized the anti-cavity ingredient "Ola Flu" in the laboratory, completing research on detection methods, component characterization, performance evaluation, safety assessment, and preparation methods [6][7]. - The new generation of "Ola Flu" toothpaste launched earlier this year demonstrates significant efficacy: 12-hour long-lasting anti-cavity protection, a 42.96% increase in enamel hardness over 28 days, a 99.9% antibacterial rate, and a 65.8% acid resistance [7]. Group 3: Market Impact and Future Prospects - The recognition as a "specialized, refined, and innovative" enterprise not only affirms the company's technological innovations but also encourages domestic brands to increase research and development investments [6][7]. - The successful development of the patented small molecule bionic fetal fat peptide in the children's skincare sector enhances the company's ability to address common skin issues in children, showing improvements in anti-sensitivity and inflammation reduction [7].

Group 1 - The "Guarding Health Future 2025 Anti-Cavity Technology Seminar" was successfully held in Hangzhou, marking a significant breakthrough in China's oral care industry with the release of the first complete safety assessment report for the raw material of Olarofluor [1] - The safety assessment report validates the safety of Olarofluor in toothpaste through comprehensive toxicological data, addressing concerns regarding its application [2][3] - The regulatory landscape for toothpaste has evolved, with the implementation of full safety assessments that require verification of key indicators such as repeated dose toxicity, genetic toxicity, and mucosal irritation risks, elevating safety standards for raw materials like Olarofluor [1][2] Group 2 - Olarofluor has been a focal point in global oral research since the 1950s, and in 2021, the company "Rabbit Mom" introduced the first age-specific Olarofluor toothpaste in China, filling a gap in the children's oral care market [2] - The company has developed a domestically sourced Olarofluor raw material with improved anti-cavity performance, achieving national patent certification and successfully transitioning from raw material to product [2] - The complete safety assessment results for Olarofluor not only address societal concerns but also provide clear guidelines for recommended usage, contributing to the high-quality development of the children's oral care industry [3]

近期，多家权威媒体聚焦中国企业在防蛀原料奥拉氟成分上的技术突破。5月8日，央视网《世界微笑日 特别节目》对国内儿童口腔护理品牌兔头妈妈首次报道，展示了其自主合成的高纯度奥拉氟，在多方检 测下，防蛀性能远超进口。 在中国5岁儿童乳牙龋患率高达70.9%的现状下，这一重大防蛀科技突破后续引发极目新闻、新京报、 凤凰网等权威媒体密集关注，争相报道其背后的科研突围之路。 奥拉氟，正是国内近年来因防蛀性能优异而非常火热的成分。其源于欧洲上世纪50年代末60年代初，距 今已有60年应用历史。据公开资料显示，奥拉氟因其特殊分子结构带来了特殊的性能，如优异的延展 性，能在牙齿表面快速铺展形成一层保护膜；另外包裹性上，可以跟牙齿表面和口腔的软组织进行结 合，不易被食物带走，对牙齿可以长效保护；此外它在促进牙齿再矿化、增加抗酸蚀能力和抑菌能力 上，都有很好的表现。 目前市面上奥拉氟牙膏丰富，但备受追捧的奥拉氟原料实际上长期依赖进口。兔头妈妈研发科学家、浙 江大学高分子化学与物理博士王莎莎在接受极目新闻采访时提到，"在去年以前，全球具有生产奥拉氟 能力的企业只有三家，全部在欧洲。""为了产品升级，我们希望能够技术共享，但被对方拒绝 ...

奥拉氟是近年来市场上火热的防蛀成分，国内多个口腔护理品牌推出奥拉氟防蛀牙膏。一面是奥拉氟防 蛀牙膏市场的繁荣发展，一面是社交媒体平台上家长们对"奥拉氟"的不同态度的讨论。根据公开报道， 兔头妈妈是国内首个引进奥拉氟的国货母婴品牌，且在今年推出自主研发的国产高纯奥拉氟。而其市场 表现，以天猫平台为例，兔头妈妈奥拉氟防蛀牙膏在细分类目下，连续霸榜天猫超市牙膏热卖榜、回购 榜、好评榜榜单TOP1。 近日，凤凰网独家专访兔头妈妈，揭秘奥拉氟技术背后的科技暗战。 跨世纪的奥拉氟早已技术垄断 在奥拉氟（Olaflur）源于欧洲上世纪50年代末60年代初，因其具备更好的防龋性能，在欧洲由数十年的 研究应用。 长期以来，欧洲原料公司垄断技术不作公开，国货品牌局限使用，不仅制约自身产品迭代，更是让国内 市场陷入同质化竞争。另外，奥拉氟合成工艺相对复杂，需要特殊设备，外界并没有可供参考的制备方 法和检测方法。整个技术体系被海外企业掌控，国货品牌面对技术壁垒，颇受掣肘。 兔头妈妈品牌合伙人代羽舟在采访中分享到，有关奥拉氟检测的标准已协同权威机构和单位完成立项。 此外，兔头妈妈旗下的奥拉氟牙膏目前根据系列分别采用国产奥拉氟和进口奥拉 ...

记者近日获悉，兔头妈妈自主研发的"高纯奥拉氟"技术不仅实现国产化替代，更是超越进口奥拉氟，这 意味着，儿童口腔护理核心技术不再"仰赖进口"，国产品牌正以科研实力打破技术垄断，推动行业标准 化升级。 预防龋齿，氟化物技术不可或缺。欧洲广泛采用"奥拉氟"这一有机氟，具有出色的再矿化能力、持久氟 化膜生成能力和低刺激性。然而，这项关键技术长期由少数海外企业掌握，国内产品要么依赖昂贵的进 口原料，要么采用传统氟化钠或单氟磷酸钠替代，难以在功效上对标国际水平，兔头妈妈的出现，为这 一局面带来新的变量。 国产品牌完成"引进"到"自造"的转变 兔头妈妈此前曾通过央视网、极目新闻等媒体的采访明确表示，希望推动儿童口腔护理行业建立更加精 细、科学的评价体系。另外，有专家指出："儿童防龋核心不在是否含氟，而在于氟化物能否安全、有 效释放。"这一点，正是兔头妈妈"奥拉氟"研发聚焦的核心命题。 当前行业中，已有针对口腔护理用品含氟量的检测方法，而针对奥拉氟含量的精确方法仍是空白。在自 主研发过程中，兔头妈妈获得了而一项检测专利"一种奥拉氟及其相关组分的检测方法"，现已经对行业 公开，通过技术支持来辅助规范化发展，能以更高安全门槛驱动 ...

携手上千家齿科诊所，一场围绕儿童口腔健康的"专业下沉"正在全国展开。近日，国内儿童口腔护理品 牌兔头妈妈通过深度合作上千家齿科诊所，构建起"前端预防-中端干预-后端追踪"的全场景服务体系， 将儿童日常专业护齿理念输送至社区与家庭，为儿童龋齿防治提供创新范本。 据悉，兔头妈妈专注儿童防龋领域，其在2021年为国内首次引进进口奥拉氟，为国内儿童防蛀市场带来 变革，到2023年启动自研创新，目前取得多项相关科研成果，覆盖奥拉氟成分的制备、检测、及衍生物 的合成。2025年1月推出新一代高纯奥拉氟牙膏产品，将成果实现产品落地。 今年，兔头妈妈以"深度协同"为战略支点，与雅贝康、赛德阳光、极橙儿童齿科等全国头部连锁机构达 成合作，覆盖3000余家专业诊所，构建起"研发-验证-服务"一体化生态。这一布局不仅打通了产品从实 验室到终端的价值链路，更以技术壁垒重构行业竞争格局，为国货品牌突破国际巨头垄断提供了新范 式。 根据公开信息，兔头妈妈和齿科深度合作两年已久，齿科基本围绕社区展开，辐射周边社区，人群渗透 心智强。通过这一社区服务的优势，兔头妈妈协助齿科完成小小牙医、口腔义诊、育儿健康小课堂等 等，直接同用户沟通，加强健 ...