Core Viewpoint - The article emphasizes the significance of magnifying endoscopy in early cancer detection, highlighting its ability to transform the diagnostic process from mere observation to detailed recognition of pathological changes, thus improving early cancer screening rates in high-risk populations [2][3][28]. PART 01: From "Seeing" to "Recognizing" - Magnifying endoscopy enhances diagnostic logic, allowing doctors to observe not just the shape of lesions but also the microstructure of mucosa and vascular patterns, which are critical for distinguishing early cancer from benign lesions [5][6]. - In esophageal early cancer diagnosis, the use of the IPCL classification system in conjunction with magnifying endoscopy achieves over 90% pathological correspondence, enabling accurate cancer grading before biopsy [7]. - The JNET classification is commonly used for colorectal lesions, allowing differentiation between inflammation, adenoma, and early cancer, significantly reducing unnecessary biopsies [12]. PART 02: Who Needs to be "Seen Clearly" - Not all patients require magnifying endoscopy, but certain high-risk groups, such as those with subtle lesions or early pathological changes, benefit significantly from this technology [19]. - A multicenter study indicated that using magnifying endoscopy for screening in men over 40 increased early cancer detection rates by 18% to 25% [19]. - For patients with chronic gastritis or intestinal metaplasia, magnifying observation notably reduces false-negative rates, aiding in the early identification of high-grade intraepithelial neoplasia [19]. PART 03: Making "Precision Examination" Easier and Closer - The successful adoption of magnifying endoscopy hinges on its usability for doctors, with advancements like one-button automatic focusing simplifying the operation [21][23]. - The technology's complexity often hinders its value, but innovations that allow for automatic focus adjustments have made it more accessible for routine clinical use [25]. - By reducing both technical and cost barriers, magnifying endoscopy is transitioning from an optional tool to a standard practice in clinical settings, enhancing efficiency for doctors and fairness for patients [26]. PART 04: Conclusion: Making "Seeing" Earlier - The true value of magnifying endoscopy lies not only in improved resolution but in changing how doctors perceive lesions, moving from macro observation to structured, micro recognition [28]. - It enables real-time assessment of pathology during procedures, allowing for earlier detection of conditions that could significantly impact patient survival [28][30]. - The integration of advanced features like 145x magnification and multi-spectral enhancement redefines the boundaries of early diagnosis, making it a fundamental capability in medical practice [29].