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夜间痒到睡不着?北大人民医院教授教你科学应对特应性皮炎
Zhong Guo Jing Ji Wang· 2025-07-30 09:53
Core Insights - The article discusses the confusion between atopic dermatitis (AD) and eczema, highlighting that AD is a specific type of eczema with distinct characteristics [1] - It emphasizes the prevalence of AD in China, with over 70 million patients, and the common misconceptions surrounding the disease [1] - The article outlines the importance of proper diagnosis and treatment methods for managing AD effectively [2][4] Group 1: Disease Understanding - Atopic dermatitis is characterized by chronic inflammation, severe itching, and recurrent episodes, with about 60% of patients also suffering from allergic rhinitis or asthma [1] - The disease has a significant familial aggregation, with a 50% chance of children developing AD if one parent is affected [1] - The "Zhang's criteria" for diagnosis requires meeting two out of three conditions: chronic or recurrent symmetrical eczema, personal or family history of allergies, and elevated serum IgE or eosinophils [1] Group 2: Treatment Approaches - The "three-dimensional anti-itch method" includes cold compresses, moisturizing creams, and medication, with innovative topical agents like Zeli Mei showing promising results [2] - Clinical data indicates that 61.5% of patients in an 8-week trial achieved complete clearance of skin lesions, with rapid itch relief observed within 2 hours [2] - The drug is priced significantly lower in China at 360 yuan compared to 1,400 USD in the U.S., easing the financial burden on patients [2] Group 3: Long-term Management - Active maintenance treatment is crucial, with recommendations for preventive use of Zeli Mei even after symptoms disappear, reducing the risk of recurrence by 60% [4] - Keeping a "itch diary" to track triggers such as temperature and diet is advised for better management of the condition [4] - The drug has been approved for use in children over 2 years old, showing over 80% clearance rate in clinical trials with minimal side effects [4]
泽立美亮相皮肤学术会议 AD治疗新突破引热议
Zhong Guo Jing Ji Wang· 2025-04-22 06:49
顾军教授特别强调,泽立美作为非激素类创新药物,不仅疗效优异、复发风险低,尤其适合儿童患者 ——无刺激性、涂抹舒适、易于接受。同时,对于成人患者,其高效性和安全性同样令人满意。值得一 提的是,泽立美领先美国在中国率先获批上市,更早为本土患者带来了新的治疗选择。 顾军教授的报告引发了与会专家的热烈响应。同济大学附属皮肤病医院邹颖教授表示,从顾军教授分享 的患者照片中可以清晰看到其止痒效果的显著改善,使用泽立美后患者搔抓行为明显减少。邹颖教授强 调:"泽立美在儿童疗效和安全性方面的优势,为临床医生提供了传统非激素药物外的全新选择,丰富 了治疗策略,可以帮助患者更好地管理病情。" 会上,杭州市第三人民医院刘苏俊教授在《特应性皮炎外用药治疗新进展》报告中指出,与此前获批用 于治疗银屑病的药物不同,泽立美专为AD设计,基于AhR调节的创新机制,展现出巨大的治疗潜力, 为医生提供了新的药物选择。 近日,备受瞩目的2025年中国中西医结合学会皮肤性病专业委员会学术年会在上海举办。本次年会围绕 皮肤性病领域的前沿进展、中西医结合特色疗法等议题展开了深入交流与探讨。作为一种特应性皮炎 (AD)新药,泽立美以其独特作用机制,为AD ...