Group 1 - The article discusses the case of a patient diagnosed with dual primary cancers, specifically laryngeal and esophageal cancer, which is a rare occurrence, representing only 20% of dual primary cancers [1] - The patient opted for proton therapy after evaluating surgical options and considering the potential risks and benefits, particularly the preservation of core functions like speech and swallowing [1] - Proton therapy is highlighted as a cutting-edge cancer treatment technology that minimizes damage to critical organs, thereby reducing the incidence of complications such as radiation pneumonitis and myocarditis [1] Group 2 - The Guangzhou Taihe Cancer Hospital Proton Center commenced operations at the end of last year, built with support from renowned institutions like MD Anderson Cancer Center and Mayo Clinic, and features the first Varian ProBeam proton therapy system in South China [2] - The center has seen a significant increase in patient consultations and treatments, with a peak of over 50 patients treated in a single day, covering a wide range of cancers including nasopharyngeal, lung, liver, and prostate cancers, as well as rare tumors resistant to traditional treatments [5] - Proton therapy at the center has improved local tumor control rates while significantly reducing adverse reactions, such as rectitis and cystitis in prostate cancer patients, and preserving quality of life in pediatric cancer treatments by avoiding damage to developing tissues [5]