Core Viewpoint - Meizhong Jiahe (2453.HK) has achieved a significant breakthrough in the treatment of choroidal malignant melanoma by successfully completing the first proton therapy in China, which preserves the patient's eye and vision, filling a treatment gap in the country [1][2]. Group 1: Treatment Innovation - The proton therapy using "pencil beam scanning" technology allows for high-dose radiation to be precisely focused on the tumor while minimizing damage to surrounding critical structures, marking a shift from destructive to functional treatment [1][2]. - Traditional treatment methods primarily involved enucleation, which resulted in permanent blindness and facial disfigurement for patients [1]. Group 2: Patient Outcomes - The first patient treated, a 45-year-old male from Hunan, experienced a significant improvement in vision from 0.1 to 0.4 within 48 hours post-treatment, with tumor markers decreasing by 90% and no complications such as corneal ulcers or retinal detachment [2]. - The patient expressed satisfaction with the treatment, stating he was able to retain his eye and continue working, contrasting with his initial expectation of undergoing enucleation [2]. Group 3: Market Potential - Proton therapy is recommended as a first-line treatment for choroidal melanoma in the 2024 NCCN guidelines, providing evidence-based support for eye-preserving strategies [2]. - With approximately 2,500 new cases of choroidal malignant melanoma diagnosed annually in China, Meizhong Jiahe's advancements in this field are expected to benefit domestic patients and create substantial market opportunities for the company [2].

"肿瘤基本完全消失了！"看到复查结果的那一刻，罹患鼻腔横纹肌肉瘤的孙女士(化名)喜极而泣。此 前，孙女士在化疗后病情持续进展，陷入绝望之际，转机出现了。经多学科团队评估，广州泰和肿瘤医 院为她制定了精准质子治疗方案。30次治疗结束后，不仅肿瘤基本消失，困扰她许久的鼻塞、反复出血 等症状也明显缓解。 罹患鼻咽癌的陈先生也是受益者之一。他10年前因鼻咽癌接受根治性放疗，2年前左颈部出现放疗诱发 性肉瘤，即便经历三次手术切除与多程化疗，病情仍复发进展。来到广州泰和肿瘤医院后，陈先生接受 了复发病灶质子放疗。通过质子调强技术，仅30次放疗后复查显示，肿瘤明显消退。 还有罹患鼻腔上颌窦神经内分泌癌的李女士(化名)曾在化疗的痛苦中苦苦挣扎，但鼻腔内的肿瘤依然肆 意生长，她鼻塞如巨石堵塞，每一次呼吸都成了艰难的抗争，同时眼眶胀痛、头痛等副作用让她度日如 年。之后经过全面评估，她来到广州泰和肿瘤医院接受质子治疗。治疗至中期，她的肿瘤退缩已超过一 半，眼球突出、眼眶胀痛、鼻塞及头痛等局部压迫症状显著改善；治疗结束时复查影像提示：肿瘤最大 径从初始 7 cm 缩减至 2 cm，听到结果的她脸上重新绽放出久违的笑容。据了解，在放疗 ...