Core Viewpoint - The article highlights the advancements in the diagnosis and treatment of brain gliomas, particularly focusing on the innovative Raman optical biopsy technology developed by Jiangsu Raman Medical Equipment Co., Ltd. This technology aims to improve the accuracy and speed of glioma diagnosis, addressing the limitations of traditional methods [2][4][14]. Group 1: Research Background - Brain gliomas account for 26.5% of central nervous system tumors, with glioblastoma (GBM) representing 46.1% of gliomas. The annual incidence rate is approximately 3.2-6.4 per 100,000 people [2]. - The median overall survival (mOS) for glioblastoma patients is only 14.6-20.9 months, with a 5-year survival rate below 3-5% [2]. - MRI is the primary diagnostic tool, but it struggles to accurately differentiate tumor subtypes and boundaries. Traditional pathological diagnosis is time-consuming and cannot meet intraoperative needs [2]. Group 2: Product Introduction - Jiangsu Raman Medical Equipment Co., Ltd. has developed a brain glioma pathological tissue analysis instrument, which utilizes Raman resonance scattering principles to detect specific chemical components and concentrations in biological tissues [3][4]. - The instrument offers real-time, rapid detection in just 1 second, providing higher accuracy at the molecular level and enabling non-invasive, intraoperative diagnostics [4]. Group 3: Market Overview - The global tissue pathology diagnostic equipment market is projected to reach $3.344 billion in 2024, growing to $5.326 billion by 2031, with a CAGR of 6.4% [9]. - The AI-assisted disease imaging analysis market is expected to reach $32.7 billion by 2025, with a CAGR of 28.4%, and China is anticipated to have the fastest growth rate, exceeding 35% [9]. - The Chinese market for tissue pathology diagnostic equipment is rapidly evolving, with significant growth expected through 2031, outpacing global averages [9]. Group 4: Competitor Analysis - Nico Corporation (USA) has developed the BrainPath system, which integrates intraoperative imaging and navigation for glioma surgery, though it comes with a high cost [10]. - European companies like Horiba and Renishaw offer Raman spectroscopy systems widely used in research and clinical trials, but these are primarily laboratory devices requiring further optimization for clinical application [10]. Group 5: Technological Advancements - A clinical trial at Beijing Tiantan Hospital is exploring new diagnostic techniques using optical electronic ex vivo brain tumor analysis instruments alongside traditional pathological examinations [5]. - Jiangsu Raman Medical Equipment Co., Ltd. has contributed to research presented at the SPIE BIOS conference, focusing on the use of portable Raman analyzers for brain tumor detection [6].

Core Insights - The article highlights the upcoming global medical technology conferences scheduled for 2025, including the first Global Aesthetic Technology Conference and the second Global Medical Technology Conference [1][15] - It discusses the recent approval of six innovative medical devices by NMPA, indicating a growing focus on advanced medical technologies in China [1] Company Summaries - **Dunbo Medical**: A high-tech company specializing in the research and production of Class III active implantable medical devices, including single-chamber and dual-chamber wireless pacemakers, and vagus nerve stimulators for heart failure [2] - **Aikang Yicheng Medical**: Established in 2003, this company focuses on spinal fixation systems and has multiple national-level research and development platforms, including a postdoctoral research workstation [3] - **Jiangsu Raman Medical Equipment**: This company specializes in Raman optical biopsy technology, providing real-time optical biopsy solutions for various medical fields, enhancing surgical efficiency and diagnostic accuracy [5] - **Singularity Medical Technology**: Engaged in organ medicine and industrial development, this company has developed a non-ischemic liver perfusion system that significantly improves transplant outcomes by maintaining organ function during transport [8] - **Shanghai United Imaging Healthcare**: Founded in 2011, this company focuses on high-end medical imaging equipment and has a comprehensive product line that includes MRI, CT, and PET/CT systems [9][11] - **Shanghai Pangying Technology**: An innovative medical technology company that has developed the Hairo hair transplant robot, providing a comprehensive solution for hair restoration with advanced visual recognition and precision control [12][14]