Core Viewpoint - Zhaoke Ophthalmology-B (06622) reported a significant decline in revenue and an increase in net loss, while advancing its drug candidates towards commercialization [1] Financial Performance - The company achieved revenue of HKD 15.803 million, a year-on-year decrease of 68.25% [1] - The net loss amounted to HKD 117 million, representing a year-on-year increase of 53.85% [1] Drug Development Progress - Three core drug candidates, including Atropine Sulfate Eye Drops, Cyclosporine Eye Gel, and Bevacizumab Vitreous Injection, have entered the New Drug Application (NDA) stage, with a goal of commercializing 12 drugs by the end of 2026 [1] Strategic Partnerships - Zhaoke Ophthalmology signed a distribution and supply agreement with PT Ferron Par Pharmaceuticals for its Atropine Sulfate Eye Drops in Indonesia, granting exclusive rights for import, promotion, distribution, marketing, and sales [1] - The agreement includes an upfront payment and potential milestone payments based on certain achievements [1]

Core Viewpoint - Zhaoke Ophthalmology (06622) reported a significant decline in revenue and an increase in net loss, while advancing its drug candidates towards commercialization [1] Financial Performance - The company achieved revenue of 15.803 million HKD, a year-on-year decrease of 68.25% [1] - Net loss amounted to 117 million HKD, reflecting a year-on-year increase of 53.85% [1] Drug Development Progress - Three core drug candidates, including Atropine Sulfate Eye Drops, Cyclosporine Eye Gel, and Bevacizumab Vitreous Injection, have entered the New Drug Application (NDA) stage, with a goal of commercializing a total of 12 drugs by the end of 2026 [1] Strategic Partnerships - The company signed a distribution and supply agreement with Indonesia's leading pharmaceutical company, PT Ferron Par Pharmaceuticals, for its core product, Atropine Sulfate Eye Drops (NVK002) [1] - Under the agreement, Zhaoke Ophthalmology grants PT Ferron exclusive rights to import, promote, distribute, market, and sell the product in Indonesia, along with receiving an upfront payment and potential milestone payments based on achievements [1]

Core Viewpoint - The company, Zhaoke Ophthalmology (06622.HK), has seen its stock price nearly double this year, making it one of the top performers in the Hong Kong biotech sector, despite reporting a loss of 117 million yuan in the first half of the year due to strategic adjustments and increased R&D spending [1][2][3]. Financial Performance - Zhaoke Ophthalmology reported a loss of 117 million yuan in the first half of the year, attributed to a shift in sales strategy focusing on top-tier hospitals and optimizing the sales team, which led to a temporary decline in generic drug sales [2]. - The company's R&D expenditure for the first half of the year was 113 million yuan, an increase compared to the same period last year [3]. Product Pipeline and Market Potential - The company aims to commercialize a total of 12 drugs by the end of 2026, with a focus on core products such as atropine sulfate eye drops, cyclosporine eye gel, and bevacizumab intravitreal injection, which are currently at the application stage for market approval [3][4]. - The demand for pediatric myopia prevention is significant, with many hospitals still using in-house formulations of atropine, indicating a substantial growth opportunity in the atropine market as approved products replace these formulations [4]. Industry Trends - The incidence of eye diseases in China is rising due to factors such as aging population, increased work and study pressure, and excessive use of electronic devices. The overall myopia rate among children and adolescents was reported at 51.9% in 2022, with varying rates across different age groups [3].